메뉴 건너뛰기




Volumn 18, Issue 6, 2006, Pages 501-509

Phosphodiesterase 11: A brief review of structure, expression and function

Author keywords

Erectile dysfunction; Phosphodiesterase; Spermatogenesis; Tadalafil

Indexed keywords

9 (2 HYDROXY 3 NONYL)ADENINE; BAY 607550; CILOMILAST; CILOSTAMIDE; DIPYRIDAMOLE; ISOBUTYLMETHYLXANTHINE; ISOENZYME; MILRINONE; PHOSPHODIESTERASE; PHOSPHODIESTERASE 11; PHOSPHODIESTERASE INHIBITOR; ROFLUMILAST; ROLIPRAM; SILDENAFIL; TADALAFIL; UNCLASSIFIED DRUG; VARDENAFIL; VINPOCETINE; ZAPRINAST; ZARDAVERINE;

EID: 33750484640     PISSN: 09559930     EISSN: 14765489     Source Type: Journal    
DOI: 10.1038/sj.ijir.3901441     Document Type: Review
Times cited : (48)

References (33)
  • 1
    • 0037380294 scopus 로고    scopus 로고
    • Phosphodiesterases as therapeutic targets
    • Lin CS, Xin ZC, Lin G, Lue TF. Phosphodiesterases as therapeutic targets. Urology 2003; 61: 685-691.
    • (2003) Urology , vol.61 , pp. 685-691
    • Lin, C.S.1    Xin, Z.C.2    Lin, G.3    Lue, T.F.4
  • 2
    • 3342892000 scopus 로고    scopus 로고
    • Comparative selectivity profiles of Tadalafil, Sildenafil and Vardenafil using an in vitro phosphodiesterase activity assay
    • Saenz de Tejada I, Angulo Frutos J, Gaudo M, Florio V. Comparative selectivity profiles of Tadalafil, Sildenafil and Vardenafil using an in vitro phosphodiesterase activity assay. Int J Impot Res 2002; 14(Suppl 4): S20-S32.
    • (2002) Int J Impot Res , vol.14 , Issue.SUPPL. 4
    • Saenz De Tejada, I.1    Angulo Frutos, J.2    Gaudo, M.3    Florio, V.4
  • 3
    • 0001825459 scopus 로고    scopus 로고
    • Selectivity of sildenafil and other phosphodiesterase type 5 (PDE5) inhibitors against all human phosphodiesterase families
    • Gbekor E, Bethel S, Fawcett L, Mount N, Phillips S. Selectivity of sildenafil and other phosphodiesterase type 5 (PDE5) inhibitors against all human phosphodiesterase families. Eur Urol Suppl 2002; 1(Suppl 1): 63.
    • (2002) Eur Urol Suppl , vol.1 , Issue.SUPPL. 1 , pp. 63
    • Gbekor, E.1    Bethel, S.2    Fawcett, L.3    Mount, N.4    Phillips, S.5
  • 4
    • 0037451871 scopus 로고    scopus 로고
    • Design, synthesis and biological activity of beta-carboline-based type-5 phosphodiesterase inhibitors
    • Maw GN, Allerton CM, Gbekor E, Million WA. Design, synthesis and biological activity of beta-carboline-based type-5 phosphodiesterase inhibitors. Bioorg Med Chem Lett 2003; 13: 1425-1428.
    • (2003) Bioorg Med Chem Lett , vol.13 , pp. 1425-1428
    • Maw, G.N.1    Allerton, C.M.2    Gbekor, E.3    Million, W.A.4
  • 5
    • 14544280630 scopus 로고    scopus 로고
    • High biochemical selectivity of tadalafil, sildenafil and vardenafil for human phosphodiesterase 5A1 (PDE5) over PDE11A4 suggests the absence of PDE11A4 cross-reaction in patients
    • Weeks JL, Zoraghi R, Beasley A, Sekhar KR, Francis SH, Corbin JD. High biochemical selectivity of tadalafil, sildenafil and vardenafil for human phosphodiesterase 5A1 (PDE5) over PDE11A4 suggests the absence of PDE11A4 cross-reaction in patients. Int J Impot Res 2005; 17: 5-9.
    • (2005) Int J Impot Res , vol.17 , pp. 5-9
    • Weeks, J.L.1    Zoraghi, R.2    Beasley, A.3    Sekhar, K.R.4    Francis, S.H.5    Corbin, J.D.6
  • 6
    • 3342991544 scopus 로고    scopus 로고
    • Potency, selectivity, and consequences of nonselectivity of PDE inhibition
    • Bischoff E. Potency, selectivity, and consequences of nonselectivity of PDE inhibition. Int J Impot Res 2004; 16(Suppl 1): S11-S14.
    • (2004) Int J Impot Res , vol.16 , Issue.SUPPL. 1
    • Bischoff, E.1
  • 7
    • 0141594650 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterases in pancreatic islets
    • Pyne NJ, Furman BL. Cyclic nucleotide phosphodiesterases in pancreatic islets. Diabetologia 2003; 46: 1179-1189.
    • (2003) Diabetologia , vol.46 , pp. 1179-1189
    • Pyne, N.J.1    Furman, B.L.2
  • 8
    • 18644376713 scopus 로고    scopus 로고
    • The next generation of phosphodiesterase inhibitors: Structural clues to ligand and substrate selectivity of phosphodiesterases
    • Manallack DT, Hughes RA, Thompson PE. The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases. J Med Chem 2005; 48: 3449-3462.
    • (2005) J Med Chem , vol.48 , pp. 3449-3462
    • Manallack, D.T.1    Hughes, R.A.2    Thompson, P.E.3
  • 9
    • 0042355363 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system
    • Maurice DH, Palmer D, Tilley DG, Dunkerley HA, Netherton SJ, Raymond DR et al. Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system. Mol Pharmacol 2003; 64: 533-546.
    • (2003) Mol Pharmacol , vol.64 , pp. 533-546
    • Maurice, D.H.1    Palmer, D.2    Tilley, D.G.3    Dunkerley, H.A.4    Netherton, S.J.5    Raymond, D.R.6
  • 10
    • 0034613203 scopus 로고    scopus 로고
    • Isolation and characterization of two novel phosphodiesterase PDE11A variants showing unique structure and tissue-specific expression
    • Yuasa K, Kotera J, Fujishige K, Michibata H, Sasaki T, Omori K. Isolation and characterization of two novel phosphodiesterase PDE11A variants showing unique structure and tissue-specific expression. J Biol Chem 2000; 275: 31469-31479.
    • (2000) J Biol Chem , vol.275 , pp. 31469-31479
    • Yuasa, K.1    Kotera, J.2    Fujishige, K.3    Michibata, H.4    Sasaki, T.5    Omori, K.6
  • 11
    • 0034819381 scopus 로고    scopus 로고
    • Identification of rat cyclic nucleotide phosphodiesterase 11A (PDE11A): Comparison of rat and human PDE11A splicing variants
    • Yuasa K, Ohgaru T, Asahina M, Omori K. Identification of rat cyclic nucleotide phosphodiesterase 11A (PDE11A): comparison of rat and human PDE11A splicing variants. Eur J Biochem 2001; 268: 4440-4448.
    • (2001) Eur J Biochem , vol.268 , pp. 4440-4448
    • Yuasa, K.1    Ohgaru, T.2    Asahina, M.3    Omori, K.4
  • 14
    • 0035160349 scopus 로고    scopus 로고
    • Genomic organization of the human phosphodiesterase PDE11A gene. Evolutionary relatedness with other PDEs containing GAF domains
    • Yuasa K, Kanoh Y, Okumura K, Omori K. Genomic organization of the human phosphodiesterase PDE11A gene. Evolutionary relatedness with other PDEs containing GAF domains. Eur J Biochem 2001; 268: 168-178.
    • (2001) Eur J Biochem , vol.268 , pp. 168-178
    • Yuasa, K.1    Kanoh, Y.2    Okumura, K.3    Omori, K.4
  • 15
    • 1642457208 scopus 로고    scopus 로고
    • Properties and functions of GAF domains in cyclic nucleotide phosphodiesterases and other proteins
    • Zoraghi R, Corbin JD, Francis SH. Properties and functions of GAF domains in cyclic nucleotide phosphodiesterases and other proteins. Mol Pharmacol 2004; 65: 267-278.
    • (2004) Mol Pharmacol , vol.65 , pp. 267-278
    • Zoraghi, R.1    Corbin, J.D.2    Francis, S.H.3
  • 16
    • 21544483186 scopus 로고    scopus 로고
    • Mammalian sperm phosphodiesterases and their involvement in receptor-mediated cell signaling important for capacitation
    • Baxendale RW, Fraser LR. Mammalian sperm phosphodiesterases and their involvement in receptor-mediated cell signaling important for capacitation. Mol Reprod Dev 2005; 71: 495-508.
    • (2005) Mol Reprod Dev , vol.71 , pp. 495-508
    • Baxendale, R.W.1    Fraser, L.R.2
  • 17
    • 0032008128 scopus 로고    scopus 로고
    • Binding of cGMP to both allosteric sites of cGMP-binding cGMPspecific phosphodiesterase (PDE5) is required for its phosphorylation
    • Turko IV, Francis SH, Corbin JD. Binding of cGMP to both allosteric sites of cGMP-binding cGMPspecific phosphodiesterase (PDE5) is required for its phosphorylation. Biochem J 1998; 329: 505-510.
    • (1998) Biochem J , vol.329 , pp. 505-510
    • Turko, I.V.1    Francis, S.H.2    Corbin, J.D.3
  • 20
    • 17144376409 scopus 로고    scopus 로고
    • Re: Montorsi et al. Vardenafil for the treatment of erectile dysfunction: A critical review of the literature based on personal clinical experience
    • Pomara G, Morelli G. Re: Montorsi et al. Vardenafil for the treatment of erectile dysfunction: a critical review of the literature based on personal clinical experience. Eur urol 2005; 47: 612-621.
    • (2005) Eur Urol , vol.47 , pp. 612-621
    • Pomara, G.1    Morelli, G.2
  • 21
    • 22644440012 scopus 로고    scopus 로고
    • 3′,5′-cyclic nucleotide phosphodiesterase 11A: Localization in human tissues
    • Loughney K, Taylor J, Florio VA. 3′,5′-cyclic nucleotide phosphodiesterase 11A: localization in human tissues. Int J Impot Res 2005; 17: 320-325.
    • (2005) Int J Impot Res , vol.17 , pp. 320-325
    • Loughney, K.1    Taylor, J.2    Florio, V.A.3
  • 23
    • 0012634420 scopus 로고    scopus 로고
    • Phosphodiesterase type 11 (PDE11) cellular localization: Progress towards defining a physiological role in testis and/or reproduction
    • Baxendale RW, Burslem F, Phillips SC. Phosphodiesterase type 11 (PDE11) cellular localization: progress towards defining a physiological role in testis and/or reproduction. J Urol 2001; 165(Suppl): 340.
    • (2001) J Urol , vol.165 , Issue.SUPPL. , pp. 340
    • Baxendale, R.W.1    Burslem, F.2    Phillips, S.C.3
  • 24
    • 0012634420 scopus 로고    scopus 로고
    • Cellular localization of phosphodiesterase type 11 (PDE11) in human corpus cavernosum and the contribution of PDE11 inhibition on the nerve stimulated relaxation
    • Baxendale RW, Wayman CP, Turner L, Phillips SC. Cellular localization of phosphodiesterase type 11 (PDE11) in human corpus cavernosum and the contribution of PDE11 inhibition on the nerve stimulated relaxation. J Urol 2001; 165(Suppl): 340.
    • (2001) J Urol , vol.165 , Issue.SUPPL. , pp. 340
    • Baxendale, R.W.1    Wayman, C.P.2    Turner, L.3    Phillips, S.C.4
  • 26
    • 18744416134 scopus 로고    scopus 로고
    • Effect of acute in vivo sildenafil or tadalafil treatments on semen parameters in patients with fertility problem, a randomized, double-blind, crossover study
    • PS-5-9
    • Pomara G, Morelli G, Turchi P, Caglieresi C, MOschini C, Canale D et al. Effect of acute in vivo sildenafil or tadalafil treatments on semen parameters in patients with fertility problem, a randomized, double-blind, crossover study. J Sex Med 2004; 2(Suppl 2): 23 (PS-5-9).
    • (2004) J Sex Med , vol.2 , Issue.SUPPL. 2 , pp. 23
    • Pomara, G.1    Morelli, G.2    Turchi, P.3    Caglieresi, C.4    Moschini, C.5    Canale, D.6
  • 29
    • 0031091039 scopus 로고    scopus 로고
    • Capacitation as a regulatory event that primes spermatozoa for the acrosome reaction and fertilization
    • de Lamirande E, Leclerc P, Gagnon C. Capacitation as a regulatory event that primes spermatozoa for the acrosome reaction and fertilization. Mol Hum Reprod 1997; 3: 175-194.
    • (1997) Mol Hum Reprod , vol.3 , pp. 175-194
    • De Lamirande, E.1    Leclerc, P.2    Gagnon, C.3
  • 30
    • 33750460697 scopus 로고    scopus 로고
    • Are prostates and male infertility related?
    • Kshirsagar A, Niederberger C. Are prostates and male infertility related? AUANEWS 2005; 10: 9-10.
    • (2005) AUANEWS , vol.10 , pp. 9-10
    • Kshirsagar, A.1    Niederberger, C.2
  • 33
    • 0042236843 scopus 로고    scopus 로고
    • Tadalafil has no detrimental effect on human spermatogenesis or reproductive hormones
    • Hellstrom WJ, Overstreet JW, Yu A, Saikali K, Shen W, Beasley Jr CM et al. Tadalafil has no detrimental effect on human spermatogenesis or reproductive hormones. J Urol 2003; 170: 887-891.
    • (2003) J Urol , vol.170 , pp. 887-891
    • Hellstrom, W.J.1    Overstreet, J.W.2    Yu, A.3    Saikali, K.4    Shen, W.5    Beasley Jr., C.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.