Thiophene backbone amide linkers, a new class of easily prepared and highly acid-labile linkers for solid-phase synthesis

Journal of Organic Chemistry

Volumn 71, Issue 18, 2006, Pages 6734-6741

  Jessing, Mikkel ^a   Brandt, Malene ^b   Jensen, Knud J ^b   Christensen, Jørn B ^a   Boas, Ulrik ^a,b,c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLATION; ALDEHYDES; AMINATION; BIOPOLYMERS; OLEFINS; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL);

3,4-ETHYLENEDIOXYTHIOPHENE (EDOT); BACKBONE AMIDE LINKERS (BAL HANDLES); CHEMOSELECTIVE NEGISHI COUPLING; MERCAPTO ACIDS; SOLID-PHASE SYNTHESIS;

NITROGEN COMPOUNDS;

3,4 ETHYLENEDIOXYTHIOPHENE; ACETAL DERIVATIVE; ACETIC ACID; ACID; ALDEHYDE; AMIDE; AMINO ACID; BIOPOLYMER; METHYL CHLORIDE; PEPTIDE DERIVATIVE; RESIN; THIOESTER; THIOL DERIVATIVE; THIOPHENE DERIVATIVE; TRIFLUOROACETIC ACID; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL BOND; CHEMICAL REACTION; CHEMICAL STRUCTURE; MOLECULE; SOLID; SYNTHESIS;

AMIDES; CHEMISTRY, ORGANIC; DIPEPTIDES; ENKEPHALIN, LEUCINE; PEPTIDES; THIOPHENES;

EID: 33750447264     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo060687r     Document Type: Article

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