COMT genotype, gender and cognition in community-dwelling, older adults

Neuroscience Letters

Volumn 409, Issue 3, 2006, Pages 205-209

  O'Hara, Ruth ^a,b   Miller, Elana ^a   Liao, Chun Ping ^b   Way, Nate ^a   Lin, Xiaoyan ^a   Hallmayer, Joachim ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Education   (United States)

Author keywords

Catechol O methyltransferase; Cognition; Gender; Older adults

Indexed keywords

CATECHOL METHYLTRANSFERASE;

ADULT; AGED; ALLELE; ARTICLE; ATTENTION; COGNITION; FEMALE; GENDER; GENOTYPE; HUMAN; HUMAN EXPERIMENT; MALE; MEMORY; NORMAL HUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; RECALL; VERBALIZATION;

AGED; AGED, 80 AND OVER; AGING; CATECHOL O-METHYLTRANSFERASE; COGNITION; COHORT STUDIES; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; SEX FACTORS;

EID: 33750438085     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2006.09.047     Document Type: Article

References (37)

1. Akil M., Kolachana B.S., Rothman D.A., Hyde T.M., Weinberger D.R., and Kleinman J.E. Catechol-O-methyltransferase genotype and dopamine regulation in the human brain. J. Neurosci. 23 (2003) 2008-2013
2. Backman L., Nyberg L., Lindenberger U., Li S.C., and Farde L. The correlative triad among aging, dopamine, and cognition: current status and future prospects. Neurosci. Biobehav. Rev. 30 6 (2006) 791-807
3. Bruder G.E., Keilp J.G., Xu H., Shikhman M., Schori E., and Gorman J.M. Catechol-O-methyltransferase (COMT) genotypes and working memory: associations with differing cognitive operations. Biol. Psychiatry 58 (2005) 901-907
4. de Frias C.M., Annerbrink K., Westberg L., Eriksson E., Adolfsson R., and Nilsson L.G. COMT gene polymorphism is associated with declarative memory in adulthood and old age. Behav. Genet. 34 (2004) 533-539
5. de Frias C.M., Annerbrink K., Westberg L., Eriksson E., Adolfsson R., and Nilsson L.G. Catechol O-methyltransferase Val158Met polymorphism is associated with cognitive performance in nondemented adults. J. Cogn. Neurosci. 17 (2005) 1018-1025
6. Drebing C.E., Van Gorp W., Stuck A.E., Mitrushina M., and Beck J. Early detection of cognitive decline in higher cognitively functioning older adults: sensitivity and specificity of a neuropsychological screening battery. J. Neuropsychol. 8 (1994) 31-37
7. Egan M.F., Goldberg T.E., Kolachana B.S., Callicott J.H., Mazzanti C.M., Straub R.E., Goldman D., and Weinberger D.R. Effect of COMT Val108/158Met genotype on frontal lobe function and risk for schizophrenia. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 6917-6922
8. M.B. First, M. Gibbon, J.B. Williams, R.L. Spitzer, SCID Screen Patient Questionnaire (SSPQ), Multi-Health Systems Inc., Toronto, ON, 1999.
9. Folstein M.F., Folstein S.E., and McHugh P.R. Mini-mental state: a practical method for grading the cognitive state of patients for the clinician. J. Psychiatr. Res. 12 (1975) 189-198
10. Galderisi S., Maj M., Kirkpatrick B., Piccardi P., Mucci A., Invernizzi G., Rossi A., Pini S., Vita A., Cassano P., Stratta P., Severino G., and del Zompo M. Catechol-O-methyltransferase Val158Met polymorphism in schizophrenia: associations with cognitive and motor impairment. Neuropsychobiology 52 (2005) 83-89
11. Gibbs S.E., and D'Esposito M. Individual capacity differences predict working memory performance and prefrontal activity following dopamine receptor stimulation. Cogn. Affect. Behav. Neurosci. 5 (2005) 212-221
12. Goldberg T.E., Egan M.F., Gscheidle T., Coppola R., Weickert T., Kolachana B.S., Goldman D., and Weinberger D.R. Executive subprocesses in working memory: relationship to catechol-O-methyltransferase Val158Met genotype and schizophrenia. Arch. Gen. Psychiatry 60 (2003) 889-896
13. Golden C.J., and Freshwater S.M. Stroop Color and Word Test (2002), Stoelting Co., Wood Dale, IL
14. Guo J.F., Yang Y.K., Chiu N.T., Yeh T.L., Chen P.S., Lee I.H., and Chu C.L. The correlation between striatal dopamine D2/D3 receptor availability and verbal intelligence quotient in healthy volunteers. Psychol. Med. 36 (2006) 547-554
15. Halbreich U. Role of estrogen in postmenopausal depression. Neurology 48 (1997) 16-19
16. Harris S.E., Wright A.F., Hayward C., Starr J.M., Whalley L.J., and Deary I.J. The functional COMT polymorphism, Val158Met, is associated with logical memory and the personality trait intellect/imagination in a cohort of healthy 79 year olds. Neurosci. Lett. 385 (2005) 1-6
17. Ho B.C., Wassink T.H., O'Leary D.S., Sheffield V.C., and Andreasen N.C. Catechol-O-methyl transferase Val158Met gene polymorphism in schizophrenia: working memory, frontal lobe MRI morphology and frontal cerebral blood flow. Mol. Psychiatry 10 (2005) 287-298
18. Joober R., Gauthier J., Lal S., Bloom D., Lalonde P., Rouleau G., Benkelfat C., and Labelle A. Catechol-O-methyltransferase Val-108/158-Met gene variants associated with performance on the Wisconsin Card Sorting Test. Arch. Gen. Psychiatry 59 (2002) 662-663
19. Kaplan E., Goodglass H., and Weintraub S. Boston Naming Test (1983), Lee & Febiger, Philadelphia
20. Kramer J.H., Delis D.C., Kaplan E., O'Donnell L., and Prifitera A. Developmental sex differences in verbal learning. Neuropsychopathology 11 (1997) 577-584
21. Lachman H.M., Papolos D.F., Saito T., Yu Y.M., Szumlanski C.L., and Weinshilboum R.M. Human catechol-O-methyltransferase polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics 6 (1996) 243-250
22. Lindamer L.A., Lohr J.B., Harris M.J., and Jeste D.V. Gender, estrogen, and schizophrenia. Psychopharmacol. Bull. 33 (1997) 221-228
23. Malhotra A.K., Kestler L.J., Mazzanti C., Bates J.A., Goldberg T., and Goldman D. A functional polymorphism in the COMT gene and performance on a test of prefrontal cognition. Am. J. Psychiatry 159 (2002) 652-654
24. Mattay V.S., Goldberg T.E., Fera F., Hariri A.R., Tessitore A., Egan M.F., Kolachana B., Callicott J.H., and Weinberger D.R. Catechol O-methyltransferase Val158-Met genotype and individual variation in the brain response to amphetamine. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 6186-6191
25. Mefford R.B., Wieland B.A., and James W.E. Repetitive psychometric measures: digit span. Psychol. Rep. 18 (1966) 3-10
26. Mozley L.H., Gur R.C., Mozley P.D., and Gur R.E. Striatal dopamine transporters and cognitive functioning in healthy men and women. Am. J. Psychiatry 158 (2001) 1492-1499
27. Nordstrom A.L., Olsson H., and Halldin C. A PET study of D2 dopamine receptor density at difference phases of the menstrual cycle. Psychiatry Res. 83 (1998) 1-6
28. O'Hara R., Yesavage J.A., Kraemer H.C., Mauricio M., Friedman L.F., and Murphy Jr. G.M. The APOE epsilon4 allele is associated with decline on delayed recall performance in community-dwelling older adults. J. Am. Geriatr. Soc. 46 (1998) 1493-1498
29. Rosa A., Peralta V., Cuesta M.J., Zarzuela A., Serrano F., Martínez-Larrea A., and Fañanás L. New evidence of association between COMT gene and prefrontal neurocognitive function in healthy individuals from sibling pairs discordant for psychosis. Am. J. Psychiatry 161 (2004) 1110-1112
30. Salthouse T.A. Working memory as a processing resource in cognitive aging. Dev. Rev. 10 (1990) 101-124
31. A. Smith, Symbol Digit Modalities Test (SDMT): Manual (revised), Western Psychological Services, Los Angeles, 1982.
32. Stefanis N.C., Van Os J., Avramopoulos D., Smyrnis N., Evdokimidis I., Hantoumi I., and Stefanis C.N. Variation in catechol-O-methyltransferase val158 met genotype associated with schizotypy but not cognition: a population study in 543 young men. Biol. Psychiatry 56 (2004) 510-515
33. Tsai S.J., Yu Y.W.Y., Chen T.J., Chen J.Y., Liou Y.J., Chen M.C., and Hong C.J. Association study of a functional catechol-O-methyltransferase-gene polymorphism and cognitive function in healthy females. Neurosci. Lett. 338 (2003) 123-126
34. Wechsler D. The Wechsler Memory Scale Revised (1987), Psychological Corporation, New York
35. Weinberger D.R. Implications of normal brain development for the pathogenesis of schizophrenia. Arch. Gen. Psychiatry 44 (1987) 660-669
36. West R.L. An application of prefrontal cortex function theory to cognitive aging. Psychol. Bull. 120 (1996) 272-292
37. Winterer G., and Goldman D. Genetics of human prefrontal function. Brain Res. Rev. 43 (2003) 134-163