Phagocytosis of PLGA microparticles in rat peritoneal exudate cells: A time-dependent study

Microscopy and Microanalysis

Volumn 12, Issue 5, 2006, Pages 399-405

  Gomes, Anderson De Jesus ^a   Lunardi, Claure Nain ^b   Caetano, Flávio Henrique ^c   Lunardi, Laurelúcia Orive ^c   Machado, Antonio Eduardo Da Hora ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Drug delivery; Macrophage; Microparticles; Peritoneal exudate cells; SEM; TEM

Indexed keywords

LACTIC ACID; MICROSPHERE; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; POLYMER;

ANIMAL; ARTICLE; CELL MEMBRANE POTENTIAL; DRUG DELIVERY SYSTEM; ELECTRON MICROSCOPY; IN VITRO STUDY; KINETICS; LIGHT; MALE; PARTICLE SIZE; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PHYSIOLOGY; RADIATION SCATTERING; RAT; SCANNING ELECTRON MICROSCOPY; ULTRASTRUCTURE;

ANIMALS; DRUG DELIVERY SYSTEMS; KINETICS; LACTIC ACID; LIGHT; MACROPHAGES, PERITONEAL; MALE; MEMBRANE POTENTIALS; MICROSCOPY, ELECTRON; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; PARTICLE SIZE; PHAGOCYTOSIS; POLYGLYCOLIC ACID; POLYMERS; RATS; SCATTERING, RADIATION;

EID: 33750341008     PISSN: 14319276     EISSN: 14358115     Source Type: Journal    
DOI: 10.1017/S1431927606060284     Document Type: Article

References (25)

1. AHSAN, F., RIVAS, I.P., KHAN, M.A. & SUÁREZ, A.I.T. (2002). Targeting to macrophage: Role of physicochemical properties of particulate carriers-lipossomes and microsperes-on the phagocytosis by macrophages. J Contr Release 79, 29-40.
2. ARTURSSON, P., ARRO, E., EDMAN, P., ERICSSON, J.L.E. & SJÖHOLM, I. (1987). Biodegradable microsphere V: Stimulation of macrophages with microparticles made of various polysaccharides. J Pharm Sci 76, 127-133.
3. CASTELLI, F., PITARRESI, G. & GIAMMONA, G. (2000). Influence of different parameters on drug release from hydrogel systems to a biomembrane model. Evaluation by differential scanning calorimetry technique. Biomaterials 21, 821-833.
4. DUNNE, M., CORRIGAN, O.I. & RAMTOOLA, Z. (2000). Influence of particle size and dissolution conditions on the degradation properties of polylactide-co-glycolide particles. Biomaterials 21, 1659-1668.
5. ESPOSITO, E., SEBBEN, S., CORTESI, R., MENEGATTI, E. & NASTRUZZI, C. (1999). Preparation and characterization of cationic microspheres for gene delivery. Int J Pharm 189, 29-41.
6. FU, F., LI, X. & WU, C. (2002). Encapsulation of phthalocyanines in biodegradable poly(sebacic anhydride) nanoparticles. Langmuir 18, 3843-3847.
7. GOMES, A.J., LUNARDI, L.O., MARCHETTI, J.M., LUNARDI, C.N. & TEDESCO, A.C. (2005). Photobiological and ultrastructural studies of nanoparticle of poly(lactic-co-glycolic acid)-containing bacteriochlorophyll-a as a photosensitizer useful for PDT treatment. Drug Deliv 12, 1-6.
8. HAYAT, M.A. (1981). Fixation for Electron Microscopy. London: Academic Press Inc.
9. JAIN, R.A. (2000). The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. Biomaterials 21, 2475-2490.
10. JEON, H.-J., JEONG, Y.-I., JANG, M.-K., PARK, Y.-H. & NAH, J.-W. (2000). Effect of solvent on the preparation of surfactant-free poly(DL-lactide-co-glycolide) nanoparticles and norfloxacin release characteristics. Int J Pharm 207, 99-108.
11. KONAN, Y.N., CHEVALLIER, J., GURNY, R. & ALLÉMANN, E. (2003). Encapsulation of p-THPP into nanoparticles: Cellular uptake, subcellular localization and effect of serum on the photodynamic activity. Photochem Photobiol 77, 638-644.
12. KREUTER, J. (2004). Influence of the surface properties on nanoparticle-mediated transport of drugs to the brain. J Nanosci Nanotechnol 4, 484-488.
13. KUMAR, M.N.V.R., BAKOWSKY, U. & LEHR, C.M. (2004). Preparation and characterization of cationic PLGA nanospheres as DNA carriers. Biomaterials 25, 1771-1777.
14. LACASSE, F.X., FILLION, M.C., PHILLIPS, N.C., ESCHER, E., MCMULLEN, J.N. & HILDGEN, P. (1998). Influence of surface properties at biodegradable microsphere surfaces: Effects on plasma protein adsorption and phagocytosis. Pharm Res 15, 312-317.
15. LAMPRECHT, A., SCHÄFER, U. & LEHR, C.-M. (2001). Size-dependent bioadhesion of micro- and nanoparticulate carriers to the inflamed colonic mucosa. Pharm Res 18, 788-793.
16. LEMOINE, D., WAUTERS, F., BOUCHEND'HOMME, S. & PREAT, V. (1998). Preparation and characterization of alginate microspheres containing a model antigen. Int J Pharm 176, 9-19.
17. MOGHIMI, S.M., HUNTER, A.C. & MURRAY, J.C. (2001). Long-circulating and target specific microparticles: Theory to practice. Pharmacol Rev 53, 283-318.
18. MURAKAMI, H., KOBAYASHI, M., KAMADA, M., TAKEUCHI, H. & KAWASHIMA, Y. (1999). Preparation of poly(DL-lactide-coglycolide) nanoparticles by modified spontaneous emulsification solvent diffusion method. Int J Pharm 187, 143-149.
19. OKADA, H. & TOGUCHI, H. (1995). Biodegradable microspheres in drug delivery. Crit Rev Ther Drug Carrier Syst 12, 1-99.
20. PANYAM, J. & LABHASETWAR, V. (2003). Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv Drug Deliv Rev 55, 329-347.
21. PANYAM, J., SAHOO, S.K., PRABHA, S., BARGAR, T. & LABHASETWAR, V. (2003). Fluorescence and electron microscopy probes for cellular and tissue uptake of poly(D,L-lactide-co-glycolide) nanoparticles. Int J Pharm 262, 1-11.
22. RUAN, G. & FENG, S.-S. (2003). Preparation and characterization of poly(lactic acid)-poly(ethyleneglycol)-poly(lactic acid) (PLA-PEG-PLA) microspheres for controlled release of paclitaxel. Biomaterials 24, 5037-5044.
23. SAHOO, S.K., PANYAM, J., PRABHA, S. & LABHASETWAR, V. (2002). Residual polyvinyl alcohol associated with poly (D,L-lactide-cogly-colide) nanoparticles affects their physical properties and cellular uptake. J Control Release 82, 105-114.
24. TABATA, Y. & IKADA, Y. (1988). Effect on the size and surface charge of polymer microspheres on their phagocytosis by macrophage. Biomaterials 9, 356-362.
25. TUNÇAY, M., ÇALIS, S., KAS, H.S., ERCAN, M.T., PEKSOY, I. & HINCAL, A.A. (2000). Diclofenac sodium incorporated PLGA (50:50) microspheres: Formulation considerations and in vitro: in vivo evaluation. Int J Pharm 195, 179-188.