Role of threonine 101 on the stability of the heme active site of cytochrome P450cam: Multiwavelength circular dichroism studies

Biochemistry

Volumn 45, Issue 42, 2006, Pages 12715-12722

  Manna, Soumen Kanti ^a   Mazumdar, Shyamalava ^a  

^a TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; HYDROGEN BONDS; ORGANIC ACIDS; PIGMENTS; SUBSTRATES; THERMODYNAMIC STABILITY;

CIRCULAR DICHROISM (CD); ELLIPTICITY; HYDROPATHY INDEX; SUBSTRATE-BOUND SPECIES;

PROTEINS;

CAMPHOR 5 MONOOXYGENASE; CYTOCHROME P450; CYTOCHROME P450 T101V; HEME; THREONINE; UNCLASSIFIED DRUG; VALINE;

ARTICLE; CIRCULAR DICHROISM; ENZYME ACTIVE SITE; ENZYME STABILITY; ENZYME SUBSTRATE; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PSEUDOMONAS PUTIDA; SPECTRAL SENSITIVITY; TEMPERATURE DEPENDENCE; THERMOSTABILITY;

AMINO ACID SEQUENCE; BINDING SITES; CAMPHOR 5-MONOOXYGENASE; CIRCULAR DICHROISM; ENZYME STABILITY; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; RESTRICTION MAPPING; SPECTROPHOTOMETRY; THERMODYNAMICS; THREONINE;

EID: 33750291246     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi060848l     Document Type: Article

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