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Volumn 8, Issue 21, 2006, Pages 4671-4673

Radical trifluoromethylation of ketone silyl enol ethers by activation with dialkylzinc

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EID: 33750287526     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0611301     Document Type: Article
Times cited : (69)

References (43)
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    • (b) Miura, K.; Takeyama, Y.; Oshima, K.; Utimoto, K. Bull. Chem. Soc. Jpn. 1991, 64, 1542-1553. Perfluoroalkylation of silyl enol ethers provided the products in good yields except for trifluoromethylation. Trifluoromethylation of ketone germyl enolates proceeds in good yield.
    • (1991) Bull. Chem. Soc. Jpn. , vol.64 , pp. 1542-1553
    • Miura, K.1    Takeyama, Y.2    Oshima, K.3    Utimoto, K.4
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    • (b) Iseki, K.; Nagai, T.; Kobayashi, Y. Tetrahedron: Asymmetry 1994, 5, 961-974. They have succeeded in trifluoromethylation by adopting Evans oxazolidinones with bulky substitutent at α position to suppress defluorination.
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  • 43
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    • note
    • Silyl enol ether of 2-methylcyclohexanone consists of thermodynamic and kinetic enolates (87:13).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.