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Some reactions involving titanium ate enolates: (a) Siegel, C.; Thornton, E. R. J. Am. Chem. Soc. 1989, 111, 5722-5728. (b) Bernardi, A.; Cavicchioli, M.; Marchionni, C.; Potenza, D.; Scolastico, C. J. Org. Chem. 1994, 59, 3690-3694. (c) Yachi, K.; Shinokubo, H.; Oshima, K. J. Am. Chem. Soc. 1999, 121, 9465-9466. (d) Han, Z.; Yorimitsu, H.; Shinokubo, H.; Oshima, K. Tetrahedron Lett. 2000, 41, 4415-4418.
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Some reactions involving titanium ate enolates: (a) Siegel, C.; Thornton, E. R. J. Am. Chem. Soc. 1989, 111, 5722-5728. (b) Bernardi, A.; Cavicchioli, M.; Marchionni, C.; Potenza, D.; Scolastico, C. J. Org. Chem. 1994, 59, 3690-3694. (c) Yachi, K.; Shinokubo, H.; Oshima, K. J. Am. Chem. Soc. 1999, 121, 9465-9466. (d) Han, Z.; Yorimitsu, H.; Shinokubo, H.; Oshima, K. Tetrahedron Lett. 2000, 41, 4415-4418.
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Some reactions involving other titanium ate comlexes: (a) Reetz, M. T.; Wenderoth, B. Tetrahedron Lett. 1982, 23, 5259-5262. (b) Reetz, M. T.; Westermann, J.; Steinbach, R.; Wenderoth, B.; Peter, R.; Ostarek, R.; Maus, S. Chem. Ber. 1985, 118, 1421-1440. (c) Reetz, M. T.; Steinbach, R.; Westermann, J.; Peter, R.; Wenderoth, B. Chem. Ber. 1985, 118, 1441-1454. (d) Takahashi, H.; Kawabata, A.; Niwa, H.; Higashiyama, K. Chem. Pharm. Bull. 1988, 36, 803-806. (e) Takahashi, H.; Tsubuki, T.; Higashiyama, K. Synthesis 1988, 238-240. (f) Takahashi, H.; Tsubuki, T.; Higashiyama, K. Chem. Pharm. Bull. 1991, 39, 260-265. (g) Bernardi, A.; Cavicchioli, M.; Scolastico, C. Tetrahedron 1993, 49, 10913-10916. (h) Bernardi, A.; Marchionni, C.; Pilati, T.; Scolastico, C. Tetrahedron Lett. 1994, 35, 6357-6360. (i) Mahrwald, R. Tetrahedron 1995, 51, 9015-9022.
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Some reactions involving other titanium ate comlexes: (a) Reetz, M. T.; Wenderoth, B. Tetrahedron Lett. 1982, 23, 5259-5262. (b) Reetz, M. T.; Westermann, J.; Steinbach, R.; Wenderoth, B.; Peter, R.; Ostarek, R.; Maus, S. Chem. Ber. 1985, 118, 1421-1440. (c) Reetz, M. T.; Steinbach, R.; Westermann, J.; Peter, R.; Wenderoth, B. Chem. Ber. 1985, 118, 1441-1454. (d) Takahashi, H.; Kawabata, A.; Niwa, H.; Higashiyama, K. Chem. Pharm. Bull. 1988, 36, 803-806. (e) Takahashi, H.; Tsubuki, T.; Higashiyama, K. Synthesis 1988, 238-240. (f) Takahashi, H.; Tsubuki, T.; Higashiyama, K. Chem. Pharm. Bull. 1991, 39, 260-265. (g) Bernardi, A.; Cavicchioli, M.; Scolastico, C. Tetrahedron 1993, 49, 10913-10916. (h) Bernardi, A.; Marchionni, C.; Pilati, T.; Scolastico, C. Tetrahedron Lett. 1994, 35, 6357-6360. (i) Mahrwald, R. Tetrahedron 1995, 51, 9015-9022.
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Some reactions involving other titanium ate comlexes: (a) Reetz, M. T.; Wenderoth, B. Tetrahedron Lett. 1982, 23, 5259-5262. (b) Reetz, M. T.; Westermann, J.; Steinbach, R.; Wenderoth, B.; Peter, R.; Ostarek, R.; Maus, S. Chem. Ber. 1985, 118, 1421-1440. (c) Reetz, M. T.; Steinbach, R.; Westermann, J.; Peter, R.; Wenderoth, B. Chem. Ber. 1985, 118, 1441-1454. (d) Takahashi, H.; Kawabata, A.; Niwa, H.; Higashiyama, K. Chem. Pharm. Bull. 1988, 36, 803-806. (e) Takahashi, H.; Tsubuki, T.; Higashiyama, K. Synthesis 1988, 238-240. (f) Takahashi, H.; Tsubuki, T.; Higashiyama, K. Chem. Pharm. Bull. 1991, 39, 260-265. (g) Bernardi, A.; Cavicchioli, M.; Scolastico, C. Tetrahedron 1993, 49, 10913-10916. (h) Bernardi, A.; Marchionni, C.; Pilati, T.; Scolastico, C. Tetrahedron Lett. 1994, 35, 6357-6360. (i) Mahrwald, R. Tetrahedron 1995, 51, 9015-9022.
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Some reactions involving other titanium ate comlexes: (a) Reetz, M. T.; Wenderoth, B. Tetrahedron Lett. 1982, 23, 5259-5262. (b) Reetz, M. T.; Westermann, J.; Steinbach, R.; Wenderoth, B.; Peter, R.; Ostarek, R.; Maus, S. Chem. Ber. 1985, 118, 1421-1440. (c) Reetz, M. T.; Steinbach, R.; Westermann, J.; Peter, R.; Wenderoth, B. Chem. Ber. 1985, 118, 1441-1454. (d) Takahashi, H.; Kawabata, A.; Niwa, H.; Higashiyama, K. Chem. Pharm. Bull. 1988, 36, 803-806. (e) Takahashi, H.; Tsubuki, T.; Higashiyama, K. Synthesis 1988, 238-240. (f) Takahashi, H.; Tsubuki, T.; Higashiyama, K. Chem. Pharm. Bull. 1991, 39, 260-265. (g) Bernardi, A.; Cavicchioli, M.; Scolastico, C. Tetrahedron 1993, 49, 10913-10916. (h) Bernardi, A.; Marchionni, C.; Pilati, T.; Scolastico, C. Tetrahedron Lett. 1994, 35, 6357-6360. (i) Mahrwald, R. Tetrahedron 1995, 51, 9015-9022.
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Some reactions involving other titanium ate comlexes: (a) Reetz, M. T.; Wenderoth, B. Tetrahedron Lett. 1982, 23, 5259-5262. (b) Reetz, M. T.; Westermann, J.; Steinbach, R.; Wenderoth, B.; Peter, R.; Ostarek, R.; Maus, S. Chem. Ber. 1985, 118, 1421-1440. (c) Reetz, M. T.; Steinbach, R.; Westermann, J.; Peter, R.; Wenderoth, B. Chem. Ber. 1985, 118, 1441-1454. (d) Takahashi, H.; Kawabata, A.; Niwa, H.; Higashiyama, K. Chem. Pharm. Bull. 1988, 36, 803-806. (e) Takahashi, H.; Tsubuki, T.; Higashiyama, K. Synthesis 1988, 238-240. (f) Takahashi, H.; Tsubuki, T.; Higashiyama, K. Chem. Pharm. Bull. 1991, 39, 260-265. (g) Bernardi, A.; Cavicchioli, M.; Scolastico, C. Tetrahedron 1993, 49, 10913-10916. (h) Bernardi, A.; Marchionni, C.; Pilati, T.; Scolastico, C. Tetrahedron Lett. 1994, 35, 6357-6360. (i) Mahrwald, R. Tetrahedron 1995, 51, 9015-9022.
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Some reactions involving other titanium ate comlexes: (a) Reetz, M. T.; Wenderoth, B. Tetrahedron Lett. 1982, 23, 5259-5262. (b) Reetz, M. T.; Westermann, J.; Steinbach, R.; Wenderoth, B.; Peter, R.; Ostarek, R.; Maus, S. Chem. Ber. 1985, 118, 1421-1440. (c) Reetz, M. T.; Steinbach, R.; Westermann, J.; Peter, R.; Wenderoth, B. Chem. Ber. 1985, 118, 1441-1454. (d) Takahashi, H.; Kawabata, A.; Niwa, H.; Higashiyama, K. Chem. Pharm. Bull. 1988, 36, 803-806. (e) Takahashi, H.; Tsubuki, T.; Higashiyama, K. Synthesis 1988, 238-240. (f) Takahashi, H.; Tsubuki, T.; Higashiyama, K. Chem. Pharm. Bull. 1991, 39, 260-265. (g) Bernardi, A.; Cavicchioli, M.; Scolastico, C. Tetrahedron 1993, 49, 10913-10916. (h) Bernardi, A.; Marchionni, C.; Pilati, T.; Scolastico, C. Tetrahedron Lett. 1994, 35, 6357-6360. (i) Mahrwald, R. Tetrahedron 1995, 51, 9015-9022.
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Some reactions involving other titanium ate comlexes: (a) Reetz, M. T.; Wenderoth, B. Tetrahedron Lett. 1982, 23, 5259-5262. (b) Reetz, M. T.; Westermann, J.; Steinbach, R.; Wenderoth, B.; Peter, R.; Ostarek, R.; Maus, S. Chem. Ber. 1985, 118, 1421-1440. (c) Reetz, M. T.; Steinbach, R.; Westermann, J.; Peter, R.; Wenderoth, B. Chem. Ber. 1985, 118, 1441-1454. (d) Takahashi, H.; Kawabata, A.; Niwa, H.; Higashiyama, K. Chem. Pharm. Bull. 1988, 36, 803-806. (e) Takahashi, H.; Tsubuki, T.; Higashiyama, K. Synthesis 1988, 238-240. (f) Takahashi, H.; Tsubuki, T.; Higashiyama, K. Chem. Pharm. Bull. 1991, 39, 260-265. (g) Bernardi, A.; Cavicchioli, M.; Scolastico, C. Tetrahedron 1993, 49, 10913-10916. (h) Bernardi, A.; Marchionni, C.; Pilati, T.; Scolastico, C. Tetrahedron Lett. 1994, 35, 6357-6360. (i) Mahrwald, R. Tetrahedron 1995, 51, 9015-9022.
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Some reactions involving other titanium ate comlexes: (a) Reetz, M. T.; Wenderoth, B. Tetrahedron Lett. 1982, 23, 5259-5262. (b) Reetz, M. T.; Westermann, J.; Steinbach, R.; Wenderoth, B.; Peter, R.; Ostarek, R.; Maus, S. Chem. Ber. 1985, 118, 1421-1440. (c) Reetz, M. T.; Steinbach, R.; Westermann, J.; Peter, R.; Wenderoth, B. Chem. Ber. 1985, 118, 1441-1454. (d) Takahashi, H.; Kawabata, A.; Niwa, H.; Higashiyama, K. Chem. Pharm. Bull. 1988, 36, 803-806. (e) Takahashi, H.; Tsubuki, T.; Higashiyama, K. Synthesis 1988, 238-240. (f) Takahashi, H.; Tsubuki, T.; Higashiyama, K. Chem. Pharm. Bull. 1991, 39, 260-265. (g) Bernardi, A.; Cavicchioli, M.; Scolastico, C. Tetrahedron 1993, 49, 10913-10916. (h) Bernardi, A.; Marchionni, C.; Pilati, T.; Scolastico, C. Tetrahedron Lett. 1994, 35, 6357-6360. (i) Mahrwald, R. Tetrahedron 1995, 51, 9015-9022.
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Mahrwald, R.1
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14844365250
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note
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9b showed that the ketone was formed in the generation of the titanium ate enolate (although this is only mentioned in the foot note of Figure 2). This fact also supports the proposed mechanism.
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42
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0000449913
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Review of the construction of quaternary carbon centers: (a) Martin, S. F. Tetrahedron 1980, 36, 419-460. (b) Fuji, K. Chem. Rev. 1993, 93, 2037-2066. (c) Corey, E. J.; Guzman-Perez, A. Angew. Chem., Int. Ed. 1998, 37, 388-401. (d) Denissova, I.; Barriault, L. Tetrahedron 2003, 59, 10105-10146.
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(1980)
Tetrahedron
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Martin, S.F.1
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43
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0001521888
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Review of the construction of quaternary carbon centers: (a) Martin, S. F. Tetrahedron 1980, 36, 419-460. (b) Fuji, K. Chem. Rev. 1993, 93, 2037-2066. (c) Corey, E. J.; Guzman-Perez, A. Angew. Chem., Int. Ed. 1998, 37, 388-401. (d) Denissova, I.; Barriault, L. Tetrahedron 2003, 59, 10105-10146.
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(1993)
Chem. Rev.
, vol.93
, pp. 2037-2066
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Fuji, K.1
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44
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0032473509
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Review of the construction of quaternary carbon centers: (a) Martin, S. F. Tetrahedron 1980, 36, 419-460. (b) Fuji, K. Chem. Rev. 1993, 93, 2037-2066. (c) Corey, E. J.; Guzman-Perez, A. Angew. Chem., Int. Ed. 1998, 37, 388-401. (d) Denissova, I.; Barriault, L. Tetrahedron 2003, 59, 10105-10146.
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(1998)
Angew. Chem., Int. Ed.
, vol.37
, pp. 388-401
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Corey, E.J.1
Guzman-Perez, A.2
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45
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0344064789
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Review of the construction of quaternary carbon centers: (a) Martin, S. F. Tetrahedron 1980, 36, 419-460. (b) Fuji, K. Chem. Rev. 1993, 93, 2037-2066. (c) Corey, E. J.; Guzman-Perez, A. Angew. Chem., Int. Ed. 1998, 37, 388-401. (d) Denissova, I.; Barriault, L. Tetrahedron 2003, 59, 10105-10146.
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(2003)
Tetrahedron
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, pp. 10105-10146
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Denissova, I.1
Barriault, L.2
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11144231136
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Kimura, M.; Yamazaki, T.; Kitazume, T.; Kubota, T. Org. Lett. 2004, 6, 4651-4654.
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Org. Lett.
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Kimura, M.1
Yamazaki, T.2
Kitazume, T.3
Kubota, T.4
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14844356526
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Silyl enol ether of α-Me cyclohexanone consists of thermodynamic enolate:kinetic enolate = 87:13.
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48
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14844342091
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note
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Silyl enol ether of α-Ph cyclohexanone contains only thermodynamic enolate.
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