Discrete MBL-MASP complexes show wide inter-individual variability in concentration: Data from UK vs Armenian populations

International Journal of Immunopathology and Pharmacology

Volumn 19, Issue 3, 2006, Pages 567-580

  Mayilyan, K R ^a,b   Presanis, J S ^a   Arnold, J N ^a   Sim, R B ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b INSTITUTE OF MOLECULAR BIOLOGY   (Armenia)

Author keywords

Caucasoid population; MBL; MBL associated serine proteases; MBL MASP complex

Indexed keywords

MANNAN BINDING LECTIN; OLIGOMER; PROTEIN MASP 1; PROTEIN MASP 2; PROTEIN MASP 3; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ADULT; AGING; ARTICLE; CIGARETTE SMOKING; CIRCULATION; CONTROLLED STUDY; DEMOGRAPHY; GENE FREQUENCY; GENETIC VARIABILITY; HUMAN; MICROORGANISM; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; STOICHIOMETRY; UNITED KINGDOM; USSR;

EID: 33750090116     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463200601900313     Document Type: Article

References (42)

1. Fujita T., M. Matsushita and Y. Endo. 2004. The lectin-complement pathway-its role in innate immunity and evolution. Immunol. Rev. 198:185.
2. Matsushita M. and T. Fujita. 1992. Activation of the classical complement pathway by mannose-binding protein in association with a novel Cls-like serine protease. J. Exp. Med. 176:1497.
3. Thiel S., T. Vorup-Jensen, C.M. Stover, W. Schwaeble, S.B. Laursen, K. Poulsen, A.C. Willis, P. Eggleton, S. Hansen, U. Holmskov, K.B. Reid and J.C. Jensenius. 1997. A second serine protease associated with mannan-binding lectin that activates complement. Nature 386:506.
4. Dahl M.R., S. Thiel, M. Matsushita, T. Fujita, A.C. Willis, T. Christensen, T. Vorup-Jensen and J.C. Jensenius. 2001. MASP-3 and its association with distinct complexes of the mannan-binding lectin complement activation pathway. Immunity 15:127.
5. Stover C.M., S. Thiel, M. Thelen, N.J. Lynch, T. Vorup-Jensen, J.C. Jensenius and W.J. Schwaeble. 1999. Two constituents of the initiation complex of the mannan-binding lectin activation pathway of complement are encoded by a single structural gene. J. Immunol. 162:3481.
6. Takahashi M., Y. Endo, T. Fujita and M. Matsushita. 1999. A truncated form of mannose-binding lectin-associated serine protease (MASP)-2 expressed by alternative polyadenylation is a component of the lectin complement pathway. Int. Immunol. 11:859.
7. Holmskov U., R. Malhotra, R.B. Sim and J.C. Jensenius. 1994. Collectins: collagenous C-type lectins of the innate immune defense system. Immunol. Today 15:67.
8. Hajela K., M. Kojima, G. Ambrus, K.H. Wong, B.E. Moffatt, J. Ferluga, S. Hajela, P. Gal and R.B. Sim. 2002. The biological functions of MBL-associated serine proteases (MASPs). Immunobiology 205:467.
9. Presanis J.S., M. Kojima and R.B. Sim. 2003. Biochemistry and genetics of mannan-binding lectin (MBL). Biochem. Soc. Trans. 31:748.
10. Vorup-Jensen T., S.V. Petersen, A.G. Hansen, K. Poulsen, W. Schwaeble, R.B. Sim, K.B. Reid, S.J. Davis, S. Thiel and J.C. Jensenius. 2000. Distinct pathways of mannan-binding lectin (MBL)- and Cl-complex autoactivation revealed by reconstitution of MBL with recombinant MBL-associated serine protease-2. J. Immunol. 165:2093.
11. Malhotra R., S. Thiel, K.B. Reid and R.B. Sim. 1990. Human leukocyte C1q receptor binds other soluble proteins with collagen domains. J. Exp. Med. 172:955.
12. Ogden C.A., A. deCathelineau, P.R. Hoffmann, D. Bratton, B. Ghebrehiwet, V.A. Fadok and P.M. Henson. 2001. C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells. J. Exp. Med. 194:781.
13. Chen C.B. and R. Wallis. 2004. Two mechanisms for mannose-binding protein modulation of the activity of its associated serine proteases. J. Biol. Chem. 279:26058.
14. Stengaard-Pedersen K., S. Thiel, M. Gadjeva, M. Moller-Kristensen, R. Sorensen, L.T. Jensen, A.G. Sjoholm, L. Fugger and J.C. Jensenius. 2003. Inherited deficiency of mannan-binding lectin-associated serine protease 2. N. Engl. J. Med. 349:554.
15. Turner M.W. and R.M. Hamvas. 2000. Mannose-binding lectin: structure, function, genetics and disease associations. Rev. Immunogenet. 2:305.
16. Peterslund N.A., C. Koch, J.C. Jensenius and S. Thiel. 2001. Association between deficiency of mannose-binding lectin and severe infections after chemotherapy. Lancet 358:637.
17. Dumestre-Perard C., D. Ponard, G.J. Arlaud, N. Monnier, R.B. Sim and M.G. Colomb. 2002. Evaluation and clinical interest of mannan binding lectin function in human plasma. Mol. Immunol. 39:465.
18. Seelen M.A., A. Roos, J. Wieslander, T.E. Mollnes, A.G. Sjoholm, R. Wurzner, M. Loos, F. Tedesco, R.B. Sim, P. Garred, E. Alexopoulos, M.W. Turner and M.R. Daha. 2005. Functional analysis of the classical, alternative and MBL pathways of the complement system: standardization and validation of a simple ELISA. J. Immunol. Methods 296:187.
19. Yokota Y., T. Arai and T. Kawasaki. 1995. Oligomeric structures required for complement activation of serum mannan-binding proteins. J. Biochem. (Tokyo) 117:414.
20. Wallis R. and K. Drickamer. 1999. Molecular determinants of oligomer formation and complement fixation in mannose-binding proteins. J. Biol. Chem. 274:3580.
21. Garred P., F. Larsen, H.O. Madsen and C. Koch. 2003. Mannose-binding lectin deficiency-revisited. Mol. Immunol. 40:73.
22. Mayilyan K.R., J.S. Presanis, J.A. Arnold, K. Hajela and R.S. Sim. 2006. Heterogeneity of MBL-MASP complexes. Mol. Immunol. 43:1286
23. Madsen H.O., P. Garred, S. Thiel, J.A. Kurtzhals, L.U. Lamm, L.P. Ryder and A. Svejgaard. 1995. Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein. J. Immunol. 155:3013.
24. Matsushita M., R.A. Ezekowitz and T. Fujita. 1995. The Gly-54→Asp allelic form of human mannose-binding protein (MBP) fails to bind MBP-associated serine protease. Biochem. J. 311:1021.
25. Lipscombe R.J., D.W. Beatty, M. Ganczakowski, E. A. Goddard, T. Jenkins, Y.L. Lau, A.B. Spurdle, M. Sumiya, J.A. Summerfield and M.W. Turner. 1996. Mutations in the human mannose-binding protein gene: frequencies in several population groups. Eur. J. Hum. Genet. 4:13.
26. Kilpatrick D.C. 2002. Mannan-binding lectin: clinical significance and applications. Biochim. Biophys. Acta 1572:401.
27. Arnold J.N., C.M. Radcliffe, M.R. Wormald, L. Royle, D.J. Harvey, M. Crispin, R.A. Dwek, R.B. Sim and P.M. Rudd. 2004. The glycosylation of human serum IgD and IgE and the accessibility of identified oligomannose structures for interaction with mannan-binding lectin. J. Immunol. 173:6831.
28. Tan S.M., M.C. Chung, O.L. Kon, S. Thiel, S.H. Lee and J. Lu. 1996. Improvements on the purification of mannan-binding lectin and demonstration of its Ca(2+)-independent association with a Cls-like serine protease. Biochem. J. 319:329.
29. Heinrikson R.L. and S.C. Meredith. 1984. Amino acid analysis by reverse-phase high-performance liquid chromatography: precolumn derivatization with phenylisothiocyanate. Anal. Biochem. 136:65.
30. Presanis J.S., K. Hajela, G. Ambrus, P. Gal and R.B. Sim. 2004. Differential substrate and inhibitor profiles for human MASP-1 and MASP-2. Mol. Immunol. 40:921.
31. Dodds A.W. 1993. Small-scale preparation of complement components C3 and C4. Methods Enzymol. 223:46.
32. Crosdale D.J., W.E. Ollier, W. Thomson, P.A. Dyer, J. Jensenious, R.W. Johnson and K.V. Poulton. 2000. Mannose binding lectin (MBL) genotype distributions with relation to serum levels in UK Caucasoids. Eur. J. Immunogen. 27:111.
33. Kilpatrick D.C. 1997. Mannan binding protein in sera positive for rheumatoid factor. Br. J. Rheumatol. 36:207.
34. Thiel S., U. Holmskov, L. Hviid, S.B. Laursen and J.C. Jensenius. 1992. The concentration of the C-type lectin, mannan-binding protein, in human plasma increases during an acute phase response. Clin. Exp. Immunol. 90:31.
35. Dunn D.L. and R.L. Simmons. 1982. Fibrin in peritonitis. III. The mechanism of bacterial trapping by polymerizing fibrin. Surgery 92:513.
36. Rotstein O.D. 1992. Role of fibrin deposition in the pathogenesis of intra-abdominal infection. Eur. J. Clin. Microbiol. Infect. Dis. 11:1064.
37. van Oss C.J. 1978. Phagocytosis as a surface phenomenon. Annu. Rev. Microbiol. 32:19.
38. Kay A.B., D.S. Pepper and R. McKenzie. 1974. The identification of fibrinopeptide B as a chemotactic agent derived from human fibrinogen. Br. J. Haematol. 27:669.
39. Thiel S., S.V. Petersen, T. Vorup-Jensen, M. Matsushita, T. Fujita, C.M. Stover, W.J. Schwaeble and J.C. Jensenius. 2000. Interaction of C1q and mannan-binding lectin (MBL) with C1r, C1s, MBL-associated serine proteases 1 and 2, and the MBL-associated protein MAp19. J. Immunol. 165:878.
40. Moller-Kristensen M., J.C. Jensenius, L. Jensen, N. Thielens, V. Rossi, G. Arlaud and S. Thiel. 2003. Levels of mannan-binding lectin-associated serine protease-2 in healthy individuals. J. Immunol. Methods 282:159.
41. Cseh S., L. Vera, M. Matsushita, T. Fujita, G.J. Arlaud and N.M. Thielens. 2002. Characterization of the interaction between L-ficolin/p35 and mannan-binding lectin-associated serine proteases-1 and -2. J. Immunol. 169:5735.
42. Wong N.K., M. Kojima, J. Dobo, G. Ambrus and R.B. Sim. 1999. Activities of the MBL-associated serine proteases (MASPs) and their regulation by natural inhibitors. Mol. Immunol. 36:853.