Reductive cyclisation of 2-cyanomethyl-3-nitrobenzoates

Letters in Organic Chemistry

Volumn 3, Issue 8, 2006, Pages 619-621

  Woon, Esther C Y ^a   Dhami, Archana ^a   Sunderland, Peter T ^a   Chalkley, David A ^a   Threadgill, Michael D ^a  

^a University of Bath   (United Kingdom)

Author keywords

DiBAL H; Isoquinoline; Isoquinolinone; Reductive cyclisation

Indexed keywords

EID: 33750086630     PISSN: 15701786     EISSN: None     Source Type: Journal    
DOI: 10.2174/157017806778559581     Document Type: Article

References (10)

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4. Wong, S.-M.; Shah, B.; Shah, P.; Butt, I.C.; Woon, E.C.Y.; Wright, J.A.; Thompson, A.S.; Upton, C.; Threadgill, M.D. Tetrahedron Lett. 2002, 43, 2299-2302.
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6. 2O/hexane 1:1) gave 3 (2.8 g, 69%) as off-white crystals: mp 94-95°C (lit. [10] mp 95.5-96°C).
7. 2), evaporation and chromatography (hexane/ EtOAc 2:3) gave 4 (220 mg, 23%) [3].
8. 4 requires 311.1031).
9. 3 requires 280.0847).
10. Grob, C.A.; Weissbach, O. Helv. Chim. Acta 1961, 44, 1736-1747.