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Volumn 44, Issue 7, 2006, Pages 503-510

Antidepressant effect of baicalin extracted from the root of Scutellaria baicalensis in mice and rats

Author keywords

Antidepressant effect; Baicalin; Chronic mild stress; Forced swimming test; Monoamine oxidase; Scutellaria baicalensis G.; Tail suspension test

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; ANTIDEPRESSANT AGENT; BAICALIN; FLAVONOID; FLUOXETINE; SCUTELLARIA BAICALENSIS EXTRACT;

EID: 33750063969     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.1080/13880200600878684     Document Type: Article
Times cited : (37)

References (49)
  • 1
    • 0031830782 scopus 로고    scopus 로고
    • Solubilized hypericin and pseudohypericin from Hypercum perforatum exert antidepressant activity in the forced swimming test
    • Butterweck V, Petereit F, Winterhoff H, Nahrstedt, A (1998): Solubilized hypericin and pseudohypericin from Hypercum perforatum exert antidepressant activity in the forced swimming test. Planta Med 64: 291-294.
    • (1998) Planta Med , vol.64 , pp. 291-294
    • Butterweck, V.1    Petereit, F.2    Winterhoff, H.3    Nahrstedt, A.4
  • 2
    • 0012920667 scopus 로고
    • Charles M, McEwen J, Tabor CW, (Eds.), XVIIB. New York and London, Academic Press
    • Charles M, McEwen J, Tabor CW, (Eds.) (1977): Methods in Enzymology, XVIIB. New York and London, Academic Press, pp. 692-698.
    • (1977) Methods in Enzymology , pp. 692-698
  • 3
    • 0033061050 scopus 로고    scopus 로고
    • Endothelium-dependent contraction and direct relaxation induced by baicalin in rat mesenteric artery
    • Chen ZY, Su YL, Lau CW, Law WI, Huang Y (1999): Endothelium-dependent contraction and direct relaxation induced by baicalin in rat mesenteric artery. Eur J Pharmacol 374: 41-47.
    • (1999) Eur J Pharmacol , vol.374 , pp. 41-47
    • Chen, Z.Y.1    Su, Y.L.2    Lau, C.W.3    Law, W.I.4    Huang, Y.5
  • 4
    • 0033888542 scopus 로고    scopus 로고
    • Effect of baicalein and facetone extract of Scutellaria baicalensis on canola oil oxidation
    • Chen ZY, Su YL, Bi YR, Tsang SY, Huang Y (2000): Effect of baicalein and facetone extract of Scutellaria baicalensis on canola oil oxidation. J Am Oil Chem Soc 77: 73-78.
    • (2000) J Am Oil Chem Soc , vol.77 , pp. 73-78
    • Chen, Z.Y.1    Su, Y.L.2    Bi, Y.R.3    Tsang, S.Y.4    Huang, Y.5
  • 5
    • 0031752958 scopus 로고    scopus 로고
    • Inhibitory effect of Coptidis rhizoma and Scutellariae radix on azoxymethane-induced aberrant crypt foci formation in rat colon
    • Fukutake M, Yokota S, Kawamura H, Iizuka A, Amagaya S, Fukuda K, Komatsu Y (1998): Inhibitory effect of Coptidis rhizoma and Scutellariae radix on azoxymethane-induced aberrant crypt foci formation in rat colon. Biol Pharm Bull 21: 814-817.
    • (1998) Biol Pharm Bull , vol.21 , pp. 814-817
    • Fukutake, M.1    Yokota, S.2    Kawamura, H.3    Iizuka, A.4    Amagaya, S.5    Fukuda, K.6    Komatsu, Y.7
  • 6
    • 0031277610 scopus 로고    scopus 로고
    • Antioxidant activity of flavones from Scutellaria baicalensis in lecithin liposomes
    • Gabrielska J, Oszmianski J, Zylka R, Komorowska M (1997): Antioxidant activity of flavones from Scutellaria baicalensis in lecithin liposomes. Z Naturforsch 52: 817-823.
    • (1997) Z Naturforsch , vol.52 , pp. 817-823
    • Gabrielska, J.1    Oszmianski, J.2    Zylka, R.3    Komorowska, M.4
  • 7
    • 0028842749 scopus 로고
    • Protection by baicalein against ascorbic acid-induced lipid peroxidation of rat liver microsomes
    • Gao D, Sakurai K, Chen J, Ogiso T (1995): Protection by baicalein against ascorbic acid-induced lipid peroxidation of rat liver microsomes. Res Commun Mol Patho Pharmacol 90: 103-114.
    • (1995) Res Commun Mol Patho Pharmacol , vol.90 , pp. 103-114
    • Gao, D.1    Sakurai, K.2    Chen, J.3    Ogiso, T.4
  • 8
    • 0030003295 scopus 로고    scopus 로고
    • Inhibition of microsomal lipid peroxidation by baicalein: A possible formation of an iron-baicalein complex
    • Gao D, Sakurai K, Katoh M, Chen J, Ogiso T (1996): Inhibition of microsomal lipid peroxidation by baicalein: A possible formation of an iron-baicalein complex. Biochem Mol Biol Int 39: 215-225.
    • (1996) Biochem Mol Biol Int , vol.39 , pp. 215-225
    • Gao, D.1    Sakurai, K.2    Katoh, M.3    Chen, J.4    Ogiso, T.5
  • 9
    • 0032750323 scopus 로고    scopus 로고
    • Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi
    • Gao Z, Huang K, Yang X, Xu H (1999): Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi. Biochim Biophys Acta 1472: 643-650.
    • (1999) Biochim Biophys Acta , vol.1472 , pp. 643-650
    • Gao, Z.1    Huang, K.2    Yang, X.3    Xu, H.4
  • 11
    • 0344183096 scopus 로고    scopus 로고
    • Chronic mild unpredictable stress after noradrenergic denervation: Attenuation of behavioral and biochemical effects of DSP-4 treatment
    • Harro J, Haidkind R, Harro M, Modiri AR, Gillberg PG, Pahkla R, Matto V, Oreland L (1999): Chronic mild unpredictable stress after noradrenergic denervation: Attenuation of behavioral and biochemical effects of DSP-4 treatment. Eur Neuropsychopharm 10: 5-16.
    • (1999) Eur Neuropsychopharm , vol.10 , pp. 5-16
    • Harro, J.1    Haidkind, R.2    Harro, M.3    Modiri, A.R.4    Gillberg, P.G.5    Pahkla, R.6    Matto, V.7    Oreland, L.8
  • 12
    • 0004348195 scopus 로고
    • Antiproliferative effect of baicalein, a flavonoid from a Chinese herb, on vascular smooth muscle cell
    • Huang HC, Wang HR, Hsieh LM (1994): Antiproliferative effect of baicalein, a flavonoid from a Chinese herb, on vascular smooth muscle cell. Eur J Pharmacol 25: 191-193.
    • (1994) Eur J Pharmacol , vol.25 , pp. 191-193
    • Huang, H.C.1    Wang, H.R.2    Hsieh, L.M.3
  • 13
    • 4243943731 scopus 로고    scopus 로고
    • Antibacterial, antiviral, and antifungal herbs
    • Huang KC, ed., Boca Raton, FL, CRC Press
    • Huang KC (1999): Antibacterial, antiviral, and antifungal herbs. In: Huang KC, ed., The Pharmacology of Chinese Herbs, Boca Raton, FL, CRC Press, pp. 385-386.
    • (1999) The Pharmacology of Chinese Herbs , pp. 385-386
    • Huang, K.C.1
  • 14
    • 0031664362 scopus 로고    scopus 로고
    • The herbal medicine Sho-saiko-to inhibits growth and metastasis of malignant melanoma primarily developed in ret-transgenic mice
    • Kato M, Liu W, Yi H, Asai N, Hayakawa A, Kozaki K, Takahashi M, Nakashima I (1998): The herbal medicine Sho-saiko-to inhibits growth and metastasis of malignant melanoma primarily developed in ret-transgenic mice. J Invest Dermatol 111: 640-644.
    • (1998) J Invest Dermatol , vol.111 , pp. 640-644
    • Kato, M.1    Liu, W.2    Yi, H.3    Asai, N.4    Hayakawa, A.5    Kozaki, K.6    Takahashi, M.7    Nakashima, I.8
  • 15
    • 11844266513 scopus 로고    scopus 로고
    • Antidepressant effect of Chaihu-Shugan-San extract and its constituents in rat models of depression
    • Kim SH, Jin H, Seog DH (2005): Antidepressant effect of Chaihu-Shugan-San extract and its constituents in rat models of depression. Life Sci 76: 1297-1306.
    • (2005) Life Sci , vol.76 , pp. 1297-1306
    • Kim, S.H.1    Jin, H.2    Seog, D.H.3
  • 16
    • 0030931592 scopus 로고    scopus 로고
    • Effects of flavonoids isolated from Scutellariae radix on the production of tissue-type plasminogen activator and plasminogen activator inhibitor-1 induced by thrombin and thrombin receptor agonist peptide in cultured human umbilical vein endothelial cells
    • Kimura Y, Yokoi K, Matsushita N, Okuda H (1997): Effects of flavonoids isolated from Scutellariae radix on the production of tissue-type plasminogen activator and plasminogen activator inhibitor-1 induced by thrombin and thrombin receptor agonist peptide in cultured human umbilical vein endothelial cells. J Pharm Pharmacol 49: 816-822.
    • (1997) J Pharm Pharmacol , vol.49 , pp. 816-822
    • Kimura, Y.1    Yokoi, K.2    Matsushita, N.3    Okuda, H.4
  • 18
    • 3943074534 scopus 로고    scopus 로고
    • History of deprenyl:/the first selective inhibitor of monoamine oxidase type B
    • Knoll J (1997): History of deprenyl:/the first selective inhibitor of monoamine oxidase type B. Voprosy Meditsinskoi Khimii 43: 482-493.
    • (1997) Voprosy Meditsinskoi Khimii , vol.43 , pp. 482-493
    • Knoll, J.1
  • 19
    • 0033665173 scopus 로고    scopus 로고
    • Zinc exhibits an antidepressant-like effect in the forced swimming test in mice
    • Kroczka B, Zieba A, Dudek D, Pilc A, Nowak G (2000): Zinc exhibits an antidepressant-like effect in the forced swimming test in mice. Polish J Pharmacol 52: 403-406.
    • (2000) Polish J Pharmacol , vol.52 , pp. 403-406
    • Kroczka, B.1    Zieba, A.2    Dudek, D.3    Pilc, A.4    Nowak, G.5
  • 20
    • 0021870885 scopus 로고
    • Studies on Scutellariae radix. XII. Anti-thrombic actions of various flavonoids from Scutellariae radix
    • Kubo M, Matsuda H, Tani T, Arichi S, Kimura Y, Okuda H (1985): Studies on Scutellariae radix. XII. Anti-thrombic actions of various flavonoids from Scutellariae radix. Chem Pharm Bull 33: 2411-2415.
    • (1985) Chem Pharm Bull , vol.33 , pp. 2411-2415
    • Kubo, M.1    Matsuda, H.2    Tani, T.3    Arichi, S.4    Kimura, Y.5    Okuda, H.6
  • 22
    • 0142122137 scopus 로고    scopus 로고
    • Differential effects of natural polyphenols on neuronal survival in primary cultured central neurons against glutamate- and glucose deprivation-induced neuronal death
    • Lee H, Yang L, Wang C, Hu S, Chang S, Lee Y (2003): Differential effects of natural polyphenols on neuronal survival in primary cultured central neurons against glutamate- and glucose deprivation-induced neuronal death. Brain Res 986: 103-113.
    • (2003) Brain Res , vol.986 , pp. 103-113
    • Lee, H.1    Yang, L.2    Wang, C.3    Hu, S.4    Chang, S.5    Lee, Y.6
  • 23
    • 0141926465 scopus 로고    scopus 로고
    • Cytoprotective effect is one of common action pathways for antidepressants
    • Li YF, Liu YQ, Huang WC, Luo ZP (2003a): Cytoprotective effect is one of common action pathways for antidepressants. Acta Pharmacol Sin 24: 996-1000.
    • (2003) Acta Pharmacol Sin , vol.24 , pp. 996-1000
    • Li, Y.F.1    Liu, Y.Q.2    Huang, W.C.3    Luo, Z.P.4
  • 25
    • 0029704787 scopus 로고    scopus 로고
    • The anti-inflammatory activity of Scutellaria rivularis extracts and its active components, baicalin, baicalein and wogonin
    • Lin CC, Shieh DE (1996): The anti-inflammatory activity of Scutellaria rivularis extracts and its active components, baicalin, baicalein and wogonin. Am J Chin Med 24: 31-36.
    • (1996) Am J Chin Med , vol.24 , pp. 31-36
    • Lin, C.C.1    Shieh, D.E.2
  • 26
    • 0036837171 scopus 로고    scopus 로고
    • Exposure to chronic mild stress alters thresholds for lateral hypothalamic stimulation reward and subsequent responsiveness to amphetamine
    • Lin D, Bruijnzeel AW, Schmidt P, Markou A (2002): Exposure to chronic mild stress alters thresholds for lateral hypothalamic stimulation reward and subsequent responsiveness to amphetamine. Neuroscience 114: 925-933.
    • (2002) Neuroscience , vol.114 , pp. 925-933
    • Lin, D.1    Bruijnzeel, A.W.2    Schmidt, P.3    Markou, A.4
  • 28
    • 0029988191 scopus 로고    scopus 로고
    • Chronic psychosocial stress caused apical dendritic atrophy of hippocampal CA3 pyramidal neurons in subordinate tree shrews
    • Magarinos AM, McEwen BS, Flugge G, Fuchs E (1996): Chronic psychosocial stress caused apical dendritic atrophy of hippocampal CA3 pyramidal neurons in subordinate tree shrews. J Neurosci 16: 3534-3540.
    • (1996) J Neurosci , vol.16 , pp. 3534-3540
    • Magarinos, A.M.1    McEwen, B.S.2    Flugge, G.3    Fuchs, E.4
  • 30
    • 0028110031 scopus 로고
    • Antitumor effects of saikosaponins, baicalin and baicalein on human hepatoma cell lines
    • Motoo Y, Sawabu N (1994): Antitumor effects of saikosaponins, baicalin and baicalein on human hepatoma cell lines. Cancer Lett 86: 91-95.
    • (1994) Cancer Lett , vol.86 , pp. 91-95
    • Motoo, Y.1    Sawabu, N.2
  • 31
    • 0028903114 scopus 로고
    • Antiviral activity of plant flavonoid, 5,7,40-trihydroxy-8-methoxy flavone, from the roots of Scutellaria baicalensis against influenza A (H3N2) and B viruses
    • Nagai T, Suzuki Y, Tomimori T, Yamada H (1995): Antiviral activity of plant flavonoid, 5,7,40-trihydroxy-8-methoxy flavone, from the roots of Scutellaria baicalensis against influenza A (H3N2) and B viruses. Biol Pharm Bull 18: 295-299.
    • (1995) Biol Pharm Bull , vol.18 , pp. 295-299
    • Nagai, T.1    Suzuki, Y.2    Tomimori, T.3    Yamada, H.4
  • 32
    • 0032238675 scopus 로고    scopus 로고
    • Analysis of inhibitory effects of Scutellariae radix and baicalein on prostaglandin E2 production in rat C6 glioma cells
    • Nakahata N, Kutsuwa M, Kyo R, Kubo M, Hayashi K, Ohizumi Y (1998): Analysis of inhibitory effects of Scutellariae radix and baicalein on prostaglandin E2 production in rat C6 glioma cells. Am J Chin Med 26: 311-323.
    • (1998) Am J Chin Med , vol.26 , pp. 311-323
    • Nakahata, N.1    Kutsuwa, M.2    Kyo, R.3    Kubo, M.4    Hayashi, K.5    Ohizumi, Y.6
  • 33
    • 0027570811 scopus 로고
    • Anti-growth effects with components of Sho-saiko-to (TJ-9) on cultured human hepatoma cells
    • Okita K, Li Q, Murakamio T, Takahashi M (1993): Anti-growth effects with components of Sho-saiko-to (TJ-9) on cultured human hepatoma cells. Eur J Cancer Prev 2: 169-175.
    • (1993) Eur J Cancer Prev , vol.2 , pp. 169-175
    • Okita, K.1    Li, Q.2    Murakamio, T.3    Takahashi, M.4
  • 34
    • 0028050104 scopus 로고
    • 2 receptor binding in limbic forebrain associated with chronic mild stress-induced anhedonia and its reversal by imipramine
    • Berl
    • 2 receptor binding in limbic forebrain associated with chronic mild stress-induced anhedonia and its reversal by imipramine. Psychopharmacology (Berl) 115: 441-446.
    • (1994) Psychopharmacology , vol.115 , pp. 441-446
    • Papp, M.1    Klimek, V.2    Willner, P.3
  • 35
    • 0028356097 scopus 로고
    • Effects of imipramine on serotonergic and beta-adrenergic receptor binding in a realistic animal model of depression
    • Papp M, Klimek V, Willner P (1994b): Effects of imipramine on serotonergic and beta-adrenergic receptor binding in a realistic animal model of depression. Psychopharmacology 114: 309-314.
    • (1994) Psychopharmacology , vol.114 , pp. 309-314
    • Papp, M.1    Klimek, V.2    Willner, P.3
  • 36
    • 0033853608 scopus 로고    scopus 로고
    • The N-methyl-D-aspartate receptor, synaptic plasticity, and depressive disorder: A critical review
    • Petrie RXA, Reid IC, Stewart CA (2000): The N-methyl-D-aspartate receptor, synaptic plasticity, and depressive disorder: A critical review. Pharmacol Ther 87: 11-25.
    • (2000) Pharmacol Ther , vol.87 , pp. 11-25
    • Petrie, R.X.A.1    Reid, I.C.2    Stewart, C.A.3
  • 37
    • 0017618768 scopus 로고
    • Depression: A new animal model sensitive to antidepressant treatments
    • Porsolt RD, Le Pichon M, Jalfre M, Chatterjee SS (1977): Depression: A new animal model sensitive to antidepressant treatments. Nature 266: 730-732.
    • (1977) Nature , vol.266 , pp. 730-732
    • Porsolt, R.D.1    Le Pichon, M.2    Jalfre, M.3    Chatterjee, S.S.4
  • 38
    • 0018268297 scopus 로고
    • Behavioral despair in rats: A new model sensitive to antidepressant treatments
    • Porsolt RD, Anton G, Blavet N, Jalfre M (1978): Behavioral despair in rats: A new model sensitive to antidepressant treatments. Eur J Pharmacol 47: 379-391.
    • (1978) Eur J Pharmacol , vol.47 , pp. 379-391
    • Porsolt, R.D.1    Anton, G.2    Blavet, N.3    Jalfre, M.4
  • 39
    • 33750068486 scopus 로고    scopus 로고
    • Effect of Chaihu-Jia-Longgu-Muli decoction on monoamine neurotransmitters in the depression rat brain
    • Qu R, Meng HB, Chu W (2003): Effect of Chaihu-Jia-Longgu-Muli decoction on monoamine neurotransmitters in the depression rat brain. Pharmacology and Clinics of Chinese Materia Medica 19: 1-3.
    • (2003) Pharmacology and Clinics of Chinese Materia Medica , vol.19 , pp. 1-3
    • Qu, R.1    Meng, H.B.2    Chu, W.3
  • 40
    • 0033800486 scopus 로고    scopus 로고
    • Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders
    • Sapolsky RM (2000a): Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. Arch Gen Psychiatry 57: 925-935.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 925-935
    • Sapolsky, R.M.1
  • 41
    • 0013156802 scopus 로고    scopus 로고
    • The possibility of neurotoxicity in the hippocampus in major depression: A primer on neuron death
    • Sapolsky RM (2000b): The possibility of neurotoxicity in the hippocampus in major depression: A primer on neuron death. Biol Psychiat 15: 713-714.
    • (2000) Biol Psychiat , vol.15 , pp. 713-714
    • Sapolsky, R.M.1
  • 42
    • 0017249936 scopus 로고
    • Different inhibition of mitochondrial monoamine oxidase from brain by hashish components
    • Schurr A, Livne A (1976): Different inhibition of mitochondrial monoamine oxidase from brain by hashish components. Biochem Pharmacol 25: 1201-1203.
    • (1976) Biochem Pharmacol , vol.25 , pp. 1201-1203
    • Schurr, A.1    Livne, A.2
  • 43
    • 0029555458 scopus 로고
    • Scavenging effects of baicalin on free radicals and its protection on erythrocyte membrane from free radical injury
    • Shi HL, Zhao BL, Xin WJ (1995): Scavenging effects of baicalin on free radicals and its protection on erythrocyte membrane from free radical injury. Biochem Mol. Biol Int 35: 981-994.
    • (1995) Biochem Mol Biol Int , vol.35 , pp. 981-994
    • Shi, H.L.1    Zhao, B.L.2    Xin, W.J.3
  • 44
    • 0021990491 scopus 로고
    • The tail suspension test: A new method for screening antidepressants in mice
    • Steru L, Chermat R, Thierry B, Simon P (1985): The tail suspension test: A new method for screening antidepressants in mice. Psychopharmacology (Berlin) 85: 367-370.
    • (1985) Psychopharmacology (Berlin) , vol.85 , pp. 367-370
    • Steru, L.1    Chermat, R.2    Thierry, B.3    Simon, P.4
  • 45
    • 0026033890 scopus 로고
    • Changes in mesolimbic dopamine may explain stress induced anhedonia
    • Willner P, Klimek V, Golembiowska K, Muscat R (1991): Changes in mesolimbic dopamine may explain stress induced anhedonia. Psychobiology 19: 79-84.
    • (1991) Psychobiology , vol.19 , pp. 79-84
    • Willner, P.1    Klimek, V.2    Golembiowska, K.3    Muscat, R.4
  • 46
    • 0031440325 scopus 로고    scopus 로고
    • Validity, reliability and utility of the chronic mild stress model of depression: A 10 years review and evaluation
    • Willner P (1997): Validity, reliability and utility of the chronic mild stress model of depression: A 10 years review and evaluation. Psychopharmacology 134: 319-329.
    • (1997) Psychopharmacology , vol.134 , pp. 319-329
    • Willner, P.1
  • 47
    • 0031898408 scopus 로고    scopus 로고
    • Structural aspects of monoamine oxidase and its reversible inhibition
    • Wouters J (1998): Structural aspects of monoamine oxidase and its reversible inhibition. Curr Med Chem 5: 137-162.
    • (1998) Curr Med Chem , vol.5 , pp. 137-162
    • Wouters, J.1
  • 49
    • 0032031283 scopus 로고    scopus 로고
    • Interaction of iron with polyphenolic compounds: Application to antioxidant characterization
    • Yoshino M, Murakami K (1998): Interaction of iron with polyphenolic compounds: Application to antioxidant characterization. Anal Biochem 257: 40-44.
    • (1998) Anal Biochem , vol.257 , pp. 40-44
    • Yoshino, M.1    Murakami, K.2


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