Caspase-mediated changes in Sir2α during apoptosis

FEBS Letters

Volumn 580, Issue 25, 2006, Pages 5875-5879

  Ohsawa, Shizue ^a   Miura, Masayuki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Apoptosis; Caspase; Sir2

Indexed keywords

CASPASE; CASPASE 9; PROTEIN BCL XL; SILENT INFORMATION REGULATOR PROTEIN;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL PROTECTION; CONTROLLED STUDY; CYTOPLASM; HUMAN; HUMAN CELL; MAMMAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; APOPTOSIS; CASPASE 9; CASPASES; CELL LINE; HELA CELLS; HUMANS; MICE; MICE, INBRED C57BL; RECOMBINANT PROTEINS; SIRTUIN 1; SIRTUINS; TRANSFECTION;

CAENORHABDITIS ELEGANS; MAMMALIA; SACCHAROMYCETALES;

EID: 33750049651     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.09.051     Document Type: Article

References (18)

1. Tissenbaum H.A., and Guarente L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410 (2001) 227-230
2. Brunet A., Sweeney L.B., Sturgill J.F., Chua K.F., Greer P.L., Lin Y., Tran H., Ross S.E., Mostoslavsky R., Cohen H.Y., Hu L.S., Cheng H.L., Jedrychowski M.P., Gygi S.P., Sinclair D.A., Alt F.W., and Greenberg M.E. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303 (2004) 2011-2015
3. van der Horst A., Tertoolen L.G., de Vries-Smits L.M., Frye R.A., Medema R.H., and Burgering B.M. FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1). J. Biol. Chem. 279 (2004) 28873-28879
4. Luo J., Nikolaev A.Y., Imai S., Chen D., Su F., Shiloh A., Guarente L., and Gu W. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 107 (2001) 137-148
5. Sakamoto J., Miura T., Shimamoto K., and Horio Y. Predominant expression of Sir2alpha, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain. FEBS Lett. 556 (2004) 281-286
6. Mashima T., Oh-hara T., Sato S., Mochizuki M., Sugimoto Y., Yamazaki K., Hamada J., Tada M., Moriuchi T., Ishikawa Y., Kato Y., Tomoda H., Yamori T., and Tsuruo T. p53-defective tumors with a functional apoptosome-mediated pathway: a new therapeutic target. J. Natl. Cancer Inst. 97 (2005) 765-777
7. Ohsawa S., Hamada S., Kakinuma Y., Yagi T., and Miura M. Novel function of neuronal PAS domain protein 1 in erythropoietin expression in neuronal cells. J. Neurosci. Res. 79 (2005) 451-458
8. D'Sa C., Klocke B.J., Cecconi F., Lindsten T., Thompson C.B., Korsmeyer S.J., Flavell R.A., and Roth K.A. Caspase regulation of genotoxin-induced neural precursor cell death. J. Neurosci. Res. 74 (2003) 435-445
9. Kouroku Y., Urase K., Fujita E., Isahara K., Ohsawa Y., Uchiyama Y., Momoi M.Y., and Momoi T. Detection of activated Caspase-3 by a cleavage site-directed antiserum during naturally occurring DRG neurons apoptosis. Biochem. Biophys. Res. Commun. 247 (1998) 780-784
10. Takemoto K., Nagai T., Miyawaki A., and Miura M. Spatio-temporal activation of caspase revealed by indicator that is insensitive to environmental effects. J. Cell Biol. 160 (2003) 235-243
11. Boise L.H., Gonzalez-Garcia M., Postema C.E., Ding L., Lindsten T., Turka L.A., Mao X., Nunez G., and Thompson C.B. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74 (1993) 597-608
12. Chinnaiyan A.M., Orth K., O'Rourke K., Duan H., Poirier G.G., and Dixit V.M. Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases. J. Biol. Chem. 271 (1996) 4573-4576
13. Vaziri H., Dessain S.K., Ng Eaton E., Imai S.I., Frye R.A., Pandita T.K., Guarente L., and Weinberg R.A. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107 (2001) 149-159
14. Matsushita N., Takami Y., Kimura M., Tachiiri S., Ishiai M., Nakayama T., and Takata M. Role of NAD-dependent deacetylases SIRT1 and SIRT2 in radiation and cisplatin-induced cell death in vertebrate cells. Genes. Cells 10 (2005) 321-332
15. Chen J., Zhou Y., Mueller-Steiner S., Chen L.F., Kwon H., Yi S., Mucke L., and Gan L. SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling. J. Biol. Chem. 280 (2005) 40364-40374
16. Parker J.A., Arango M., Abderrahmane S., Lambert E., Tourette C., Catoire H., and Neri C. Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons. Nat. Genet. 37 (2005) 349-350
17. Guarente L. Sir2 links chromatin silencing, metabolism, and aging. Genes. Dev. 14 (2000) 1021-1026
18. Shore D. The Sir2 protein family: a novel deacetylase for gene silencing and more. Proc. Natl. Acad. Sci. USA 97 (2000) 14030-14032