Copolymers of pharmaceutical grade lactic acid and sebacic acid: Drug release behavior and biocompatibility

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 64, Issue 3, 2006, Pages 277-286

  Modi, Sweta ^a   Jain, Jay Prakash ^a   Domb, A J ^b   Kumar, Neeraj ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Biocompatibility; Biodegradable polymers; Drug delivery; Drug release kinetics; Microspheres; PLA PSA; Profile modeling

Indexed keywords

BUFFER; COPOLYMER; LACTIC ACID; METHOTREXATE; MICROSPHERE; POLYLACTIDE; POLYMER; SEBACIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; CONCENTRATION (PARAMETERS); CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DEGRADATION; DRUG FORMULATION; DRUG SOLUBILITY; EMULSION; ENCAPSULATION; EVAPORATION; FEMALE; GEL PERMEATION CHROMATOGRAPHY; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PARTICLE SIZE; PH; RAT; SCANNING ELECTRON MICROSCOPY; TOXICITY TESTING;

ANIMALS; BIOCOMPATIBLE MATERIALS; BUFFERS; CHEMISTRY, PHARMACEUTICAL; DECANOIC ACIDS; DICARBOXYLIC ACIDS; DRUG CARRIERS; DRUG COMPOUNDING; FEMALE; HYDROGEN-ION CONCENTRATION; INFLAMMATION; INJECTIONS, SUBCUTANEOUS; KINETICS; LACTIC ACID; METHOTREXATE; MICROSPHERES; PARTICLE SIZE; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; TIME FACTORS;

EID: 33750048145     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2006.05.013     Document Type: Article

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