Substituted poly(methyl vinyl ether-alt-maleic anhydride) for the release control and targeting of methotrexate

Archiv der Pharmazie

Volumn 331, Issue 11, 1998, Pages 347-351

  Orienti, Isabella ^a   Gentilomi, Giovanna ^a   Bigucci, Federica ^a   Luppi, Barbara ^a   Zecchi, Vittorio ^a  

^a Dept of Pharmaceutical Sciences ^*  (Italy)

Author keywords

Complexation; Methotrexate; pH dependent release; Self aggregation; Substituted poly(methyl vinyl ether alt maleic anhydride)

Indexed keywords

1,8 OCTANEDIAMINE; CARBOXYL GROUP; DEHYDROCHOLIC ACID; DRUG CARRIER; ETHYLENEDIAMINE; METHOTREXATE; PYRAN COPOLYMER; QUATERNARY AMMONIUM DERIVATIVE;

ANIMAL CELL; ARTICLE; BIOCOMPATIBILITY; CATTLE; COMPLEX FORMATION; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG MIXTURE; DRUG TARGETING; HEMOLYSIS; IONIZATION; NONHUMAN; PH; PRIORITY JOURNAL;

ANIMALS; CATTLE; CITRACONIC ANHYDRIDES; DRUG DELIVERY SYSTEMS; ERYTHROCYTES; METHOTREXATE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032433286     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4184(199811)331:11<347::AID-ARDP347>3.0.CO;2-N     Document Type: Article

References (12)

1. A. Rahman, P.S. Schein, Use of liposomes in cancer chemotherapy. In: G. Gregoriadis eds. Liposomes as drug carriers. John Wiley, New York 1988, pp. 381-400.
2. A. Gabizon, Liposomes as a drug delivery system in cancer chemotherapy. In: F.H.D. Roerdink, A.M. Kroon, eds. Drug carrier systems. New York: John Wiley and Sons, New York 1989, Vol. 9, pp. 185-212.
3. G. Gregoriadis ed., Liposomes technology 2nd ed CRC Press, Inc. Boca, FL, USA 1993.
4. D. Papahadjopoulos, A. Gabizon Liposome Targeting to tumor cells in vivo. Targeting of Drugs 2. Optimizing Strategies (G. Gregoriadis, A.C. Allison, G. Poste, eds). NATO ASI Series 1991, 199, 95-103.
5. A. Rogerson, J. Cummings, N. Willmott, A.T. Florence, J. Pharm. Pharmacol. 1988, 40, 337-342.
6. A. Rogerson, A. Baillie, A.T. Florence, J. Microencap. 1987, 4, 321-328.
7. D.J. Kerr, A. Rogerson, G.J. Morrison, A.T. Florence, S.B. Kay, Br. J. Cancer 1988, 58, 432-436.
8. C. Cable, J. Cassidy, S.B. Kaye, A.T. Florence, J. Pharm. Pharmacol. (Suppl.) 1988, 40, 31P.
9. P. Couvreur, L. Roblot-Treupel, M.F. Poupon, Adv. Drug Delivery Rev. 1990, 5, 209-230.
10. D.J. Kerr, S.B. Kaye, CRC Crit. Rev. Therap. Drug Carr. Syst. 1991, 8, 19-39.
11. J.A.Word, B.J.A. Furr, B. Valeaccia, J. Androl. 1989, 10, 478-486.
12. H.Maeda, Adv. Drug Delivery Rev. 1991, 6, 181-202.