In vitro characterization of methotrexate loaded poly(lactic-co-glycolic) acid microspheres and antitumor efficacy in Sarcoma-180 mice bearing tumor

Pharmaceutica Acta Helvetiae

Volumn 72, Issue 3, 1997, Pages 165-173

  Singh, U V ^a   Udupa, N ^a  

^a MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

Author keywords

Antitumor efficacy; In vitro release; Methotrexate; PLGA

Indexed keywords

HYDROXYPROPYLMETHYLCELLULOSE; METHOTREXATE; MICROSPHERE; POLYGLACTIN; POLYVINYL ALCOHOL;

ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MANUFACTURE; DRUG RELEASE; EMULSION; FEMALE; FLUORESCENCE; IN VITRO STUDY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; SARCOMA 180; SUBCUTANEOUS DRUG ADMINISTRATION; TECHNIQUE;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; CAPSULES; DRUG CARRIERS; DRUG COMPOUNDING; DRUG SCREENING ASSAYS, ANTITUMOR; LACTIC ACID; METHOTREXATE; MICE; MICE, INBRED BALB C; PARTICLE SIZE; POLYGLYCOLIC ACID; POLYMERS; SARCOMA 180; SURFACE PROPERTIES;

EID: 0030925675     PISSN: 00316865     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-6865(97)00013-7     Document Type: Article

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