Biotransformation of trans-4,5-dihydroxy-4,5-dihydrobenzo[a]pyrene to benzo[a]pyrene bis-diols and DNA adducts by induced rat liver microsomes

Chemical Research in Toxicology

Volumn 13, Issue 11, 2000, Pages 1125-1134

  Padgett, W T ^a   Davis, C ^a   Lambert, G ^a   Nelson, G B ^a   Ross, J A ^a   Yacopucci, M ^a   Nesnow, S ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE DERIVATIVE; FLAVONE DERIVATIVE;

ARTICLE; BIOTRANSFORMATION; DIASTEREOISOMER; DNA ADDUCT; LIVER MICROSOME; METABOLIC ACTIVATION; METABOLISM; MOLECULAR STABILITY; TRANS ISOMER;

ANIMALS; BENZO(A)PYRENE; BETA-NAPHTHOFLAVONE; BIOTRANSFORMATION; CARCINOGENS; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIHYDROXYDIHYDROBENZOPYRENES; DNA; DNA ADDUCTS; MALE; MICROSOMES, LIVER; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; RATS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM;

EID: 0033711930     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx000111b     Document Type: Article

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