Development of an in vitro potency assay for therapeutic TGFβ antagonists: The A549 cell bioassay

Journal of Immunological Methods

Volumn 316, Issue 1-2, 2006, Pages 18-26

  Rapoza, Martha L ^a   Fu, Daotian ^a   Sendak, Rebecca A ^a  

^a GENZYME CORPORATION   (United States)

Author keywords

A549; Bioassay; IL 11 ELISA (Enzyme Linked Immunosorbent Assay); In vitro; Potency; TGF antagonist; TGF 1 antibody

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; INHIBIN A; INTERLEUKIN 11; METELIMUMAB; MYELOPID; TRANSFORMING GROWTH FACTOR BETA ANTIBODY; TRANSFORMING GROWTH FACTOR BETA1;

ACCURACY; ARTICLE; BIOASSAY; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG POTENCY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; HUMAN; HUMAN CELL; IC 50; PRIORITY JOURNAL; VALIDATION PROCESS;

ANTIBODIES, MONOCLONAL; BIOLOGICAL ASSAY; CELL LINE, TUMOR; HUMANS; INHIBITORY CONCENTRATION 50; INTERLEUKIN-11; PROTEIN ISOFORMS; SENSITIVITY AND SPECIFICITY; TRANSFORMING GROWTH FACTOR BETA;

EID: 33750032042     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2006.07.009     Document Type: Article

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