Antigen trafficking and accessory cell function in respiratory epithelial cells

American Journal of Respiratory Cell and Molecular Biology

Volumn 21, Issue 3, 1999, Pages 365-379

  Salik, Erez ^a   Tyorkin, Max ^a   Mohan, Savita ^a   George, Italas ^a   Becker, Kai ^a   Oei, Erwin ^a   Kalb, Thomas ^a   Sperber, Kirk ^a,b  

^a MOUNT SINAI MEDICAL CENTER   (United States)

^b Department of Pediatrics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; B7 ANTIGEN; CD3 ANTIGEN; CD86 ANTIGEN; CD86 PROTEIN, HUMAN; FC RECEPTOR; HLA DR ANTIGEN; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN;

ANTIGEN ANTIBODY COMPLEX; ANTIGEN PRESENTING CELL; ARTICLE; BRONCHUS; CELL CULTURE; CELL LINE; CONFOCAL MICROSCOPY; DRUG EFFECT; ELECTRON MICROSCOPY; ENDOCYTOSIS; EPITHELIUM CELL; HUMAN; IMMUNOLOGY; KINETICS; LYMPHOCYTE ACTIVATION; METABOLISM; NOSE MUCOSA; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME;

ANTIGEN-ANTIBODY COMPLEX; ANTIGEN-PRESENTING CELLS; ANTIGENS; ANTIGENS, CD; ANTIGENS, CD3; ANTIGENS, CD80; ANTIGENS, CD86; BRONCHI; CELL LINE; CELLS, CULTURED; ENDOCYTOSIS; EPITHELIAL CELLS; HLA-DR ANTIGENS; HUMANS; KINETICS; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; NASAL MUCOSA; RECEPTORS, IGG; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS;

EID: 0033193095     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.21.3.3529     Document Type: Article

References (42)

1. Unamie, E. 1989. Macrophages, antigen presenting cells, and the phenomena of antigen handling and presentation. In Fundamental Immunology, 2nd ed. W. E. Paul, editor. Raven Press, New York. 567-599.
2. Mayer, L., and R. Schlien, 1987. Evidence for function of Ia molecules on gut epithelial cells in man. J. Exp. Med. 166:1471-1483.
3. Bland, P. W., and C. V. Whiting. 1989. Antigen processing by isolated intestinal villus enterocytes. Immunology 68:497-502.
4. Kalb, T. H., M. T. Chuang, Z. Marom, and L. Mayer. 1991. Evidence for accessory cell function by class II MHC antigen-presenting airway epithelial cells. Am. J. Respir. Cell Mol. Biol. 4:320-329.
5. Mezzetti, M., M. Soloperto, A. Fasoli, and S. Mattoli. 1991. Human bronchial epithelial cells stimulate CD-3 and mitogen-induced DNA synthesis in T cells but function poorly as antigen-presenting cells compared to pulmonary macrophages. J. Allergy Clin. Immunol. 87:930-938.
6. Holt, P. J., J. Oliver, N. Bilyk, C. McMenamin, P. G. McMenamin, G. Kraal, and T. Thepen. 1993. Down regulation of the antigen presenting cell function(s) of pulmonary dendritic cells by resident alveolar macrophages. J. Exp. Med. 177:397-407.
7. Kalb, T., X. Y. Yio, and L. Mayer. 1997. Human airway epithelial cells stimulate T-lymphocyte Lck and Fyn tyrosine kinase. Am. J. Respir. Cell Mol. 17:561-570.
8. Yoo, J., H. Chen, T. Kraus, D. Hirsch, S. Poylak, I. George, and K. Sperber. 1996. Altered cytokine production and accessory cell function after HIV-1 infection. J. Immunol. 157:1313-1320.
9. Sherris, D., W. Stohl, and L. Mayer. 1989. Characterization of lymphokines mediating B cell growth and differentiation from monoclonal anti-CD-3 antibody stimulated cells. J. Immunol. 142:2343-2451.
10. Polyak, S., H. Chen, D. Hirsch, I George, R. Hershberg, and K. Sperber. 1997. Impaired class II expression and antigen uptake in monocytic cells after HIV-1 infection. J. Immunol. 159:2177-2188.
11. Tatsumi, T., T. Takehara, M. Katayama, K. Mochizuki, M. Yamamoto, T. Kanto, Y. Sasaki, A. Kasahara, and N. Hayashi. 1997. Expression of co-stimulatory molecules B7-1 (CD80) and B7-2 (CD86) on human hepato-cellular carcinoma. Hepatology 25:1108-1114.
12. Brandtzaeg, P., F. L. Jahnsen, and I. N. Frastad. 1996. Immune function and immunopathology of the mucosa of the upper respiratory tract. Acta. Otolaryngol. 16:149-159.
13. Brandtzaeg, P. 1995. Immunocompetent cells of the upper airway: functions in normal and diseased mucosa, Eur. Arch. Otorhinolaryngol. 252 (Suppl. 1):S8-S21.
14. Cresswell, P. Assembly, transport, and function of MHC class II molecules. Annu. Rev. Immunol. 12:259-293.
15. Rossi, G. A., O. Sacco, B. Balbi, S. Oddera, T. Mattioni, G. Corte, C. Ravazzoni, and L. Allegra. 1990. Human ciliated bronchial epithelial cells: expression of the HLA-DR antigens and of the HLA-DR alpha gene, modulation of the HLA-DR antigens by gamma interferon and antigen presenting function in the mixed lymphocyte reaction. Am. J. Respir. Cell Mol. Biol. 3:431-139.
16. Kung, T. T., H. Jones, G. K. Adams III, S. P. Umland, W. Kreutner, R. W. Egan, R. W. Chapman, and A. S. Watnick. 1994. Characterization of a murine model of allergic pulmonary inflammation. Int. Arch. Allergy Immunol. 105:83-90.
17. Weissman, D. N., D. E. Bice, D. W. Siegel, and M. R. Schuyler, 1990. Murine lung immunity to a soluble antigen. Am. J. Respir. Cell Mol. Biol. 2:327-333.
18. Weissman, D. N., D. E. Bice, B. A. Meggenburg, P. J. Haley, G. M. Shopp, and M. R. Schuyler. 1992. Primary immunization in the canine lung: soluble antigen induces a localized response. Am. Rev. Respir. Dis. 145:6-12.
19. Kennedy, J. D., C. A. Hatfield, S. F. Fiddler, G. W. Winterrowd, J. V. Haas, J. E. Chin, and I. M. Richards. 1995. Phenotypic characterization of T lymphocytes migrating into lung tissue and the airway lumen after antigen inhalation in sensitized mice. Am. J. Respir. Cell Mol. Biol. 12:613-623.
20. Garlisi, G. C., A. Falcone, M. M. Billah, R. W. Egan, and S. P. Umland. 1996. T cells are the predominant source of interleukin-5 but not interleukin-4 mRNA expression in the lungs of antigen-challenged allergic mice. Am. J. Respir. Cell Mol. Biol. 15:420-428.
21. Ohkawara, Y., X. Lei, M. R. Stampfli, J. S. Marshall, Z. Xing, and M. Jordana. 1997. Cytokine and eosinophil responses in the lung peripheral blood, and bone marrow compartments, in a murine model of allergeninduced airways inflammation. Am. J. Respir. Cell Mol. Biol. 16:510-520.
22. Saloga, J., H. Renz, G. Lack, K. L. Bradley, G. L. Larsen, and E. W. Gelfand. 1993. Development and transfer of immediate cutaneous hypersensitivy in mice exposed to aerosolized antigen. J. Clin. Invest. 91:133-140.
23. Hamelmann, E., A. Oshiba, J. Schwarze, K. L. Bradley, J. Loader, G. L. Larsen, and E. W. Gelfand. 1997. Allergen-specific IgE and IL-5 are essential for the development of airways hyperresponsiveness. Am. J. Respir. Cell Mol. Biol. 16:674-682.
24. Bently, A. M., O. Meng, D. S. Robinson, O. Hamid, A. D. Kay, and S. R. Durham. 1993. Increases in activated T lymphocytes, eosinophils, and cytokine mRNA expression for interleukin-5 and granulocyte/macrophage colony-stimulating factor in bronchial biopsies after allergen challenge in atopic patients. Am. J. Respir. Cell Mol. Biol. 8:35-42.
25. Hancock, G. E., G. Kaplan, and Z. A. Cohn. 1988. Keratinocyte growth regulation by the products of immune cells. J. Exp. Med. 168:1395-1402.
26. Smith, S. M., D. K. P. Lee, J. Lacy, and D. L. Coleman, 1990. Rat tracheal epithelial cells produce granulocyte/macrophage colony-stimulating factor. Am. J. Respir. Cell Mol. Biol. 2:59-68.
27. Hanson, L., and P. Brandtzaeg. 1989. The mucosal defense system. In E. R. Stichm, editor. Immunologic Disorders in Infants and Children, 3rd ed. W. B. Saunders, Philadelphia: 116-155.
28. Fossum, S. 1989. Dendritic leukocytes: features of their in vivo physiology. Res. Immunol. 140:883-891.
29. Schauble, T. L., W. H. Boom, C. K. Finegan, and E. A. Rich. 1993. Characterization of suppressor function of alveolar macrophages for T lymphocyte responses to phytohemmagglutinin: cellular selectivity, reversibility, and early events in T-cell activation. Am. J. Respir. Cell Mol. Biol. 17:89-97.
30. Paine, R., A. Chavis, D. Gaposchkin, P. Christensen, C. H. Moy, L. A. Turka, and G. B. Toews. 1992. A factor secreted by a human pulmonary alveolar-like cell line blocks T cell proliferation between G1 and S phase. Am. J. Respir. Cell Mol. Biol. 6:658-668.
31. Laberge, S., S. P. Ernst, O. Ghaffar, W. W. Cruikshank, H. Kornfeld, D. M. Center, and Q. Hamid. 1997. Increased expression of interleukin-16 in bronchial biopsies of subjects with asthma. Am. J. Respir. Cell Mol. Biol. 17:193-202.
32. Atsuta, J., S. A. Sterbinsky, J. Plitt, L. M. Schweibert, B. S. Bochner, and R. P. Schleimer. 1997. Phenotypic and cytokine regulation of the BEAS-2B human bronchial epithelial cell; demonstration of inducible expression of the adhesion molecules VCAM-1 and ICAM-1. Am. J. Respir. Cell Mol. Biol. 17:571-582.
33. Israel, E. J., N. Simister, E. Freiberg, A. Caplan, and W. A. Walker. 1993. Immunoglobulin G binding sites on the human foctal intestine: a possible mechanism for the passive transfer of immunity from mother to infant. Immunology 79:77-81.
34. Berryman, M., and R. Rodewald, 1995. Beta 2-microglobulin co-distributes with heavy chain of the intestinal IgG-Fe receptor throughout the trans-epithelial transport pathway of the neonatal rat. J. Cell Sci. 108:2347-2360.
35. Killian, M., and M. W. Russell. 1994. Function of mucosal immunoglobulins, In Handbook of Mucosal Immunology. P. L. Ogra, J. Mestacky, M. E. Lamm, W. Strabre, J. R. McGhee, and J. Bienstock editors. Academic Press, Orlando, FL, 127-137.
36. Brandtzaeg, P. 1992. Humoral immune patterns of human mucosa: induction and relation to bacterial respiratory tract infections. J. Infect. Dis. 165 (Suppl.):S167-S176.
37. Tamura, S., and T. Kurata. 1997. Intranasal immunization for human application. Mucosal Immunology update 5:8-10.
38. Langerman, S., S. Palaszynski, A. Sadzienne, C. K. Stover, and S. Konig. 1994. Systemic and mucosal immunity induced by BCG vector expressing outer-surface protein A of Borellia burgdoferii. Nature 372:552-555.
39. Weiner, H. L., A. Friedman, A. Miller, and D. Hafler. 1994. Oral tolerance; immunologic mechanisms and treatment of animals and human organ-specific autoimmune diseases by oral administration of autoantigens. Annu. Rev. Immunol. 12:809-837.
40. Kuper, C. F., P. J. Koornstra, D. M. Hameleers, J. Bieuenga, B. J. Spitz, A. M. Duijuestijn, and P. J. van Breda-Vreisman. 1992. The role of nasopharyngeal lymphoid tissue. Immunol. Today 13:219-224.
41. Moldoveanu, Z., M. I., Clemens, S. J. Prince, B. R. Murphy, and J. Mestecky. 1995. Human immune responses to influenza virus vaccine administered by systemic or mucosal route. Vaccine 13:1006-1012.
42. Renauld-Mongenic, G., N. Mielcarek, J. Cornette, A. M. Schacht, A. Capron, G. Riveau, C. Lacht. 1996. Induction of mucosal immune responses against a heterologous antigen fused to filamentous hemagglutinin after intranasal immunization with recombinant Bordetella pertussis. Proc. Natl. Acad. Sci. USA 93:7944-7947.