Protective effect of monosialoganglioside GM1 against chemically induced apoptosis through targeting of mitochondrial function and iron transport

Biochemical Pharmacology

Volumn 72, Issue 10, 2006, Pages 1343-1353

  Gorria, Morgane ^a   Huc, Laurence ^a   Sergent, Odile ^a   Rebillard, Amélie ^a   Gaboriau, François ^b   Dimanche Boitrel, Marie Thérèse ^a   Lagadic Gossmann, Dominique ^a  

^a UNIVERSITÉ DE RENNES 1   (France)

^b PONTCHAILLOU UNIVERSITY HOSPITAL   (France)

Author keywords

Apoptosis; Benzo a pyrene; GM1; Intracellular pH; Iron; Lipid peroxidation; Mitochondria; Reactive oxygen species

Indexed keywords

ALCOHOL; BENZO[A]PYRENE; CASPASE 3; CHELATING AGENT; DEFERIPRONE; DEFEROXAMINE; GANGLIOSIDE GM1; IRON; IRON 55; MONOSIALOGANGLIOSIDE; PROTEIN P53; SODIUM PROTON EXCHANGE PROTEIN 1;

ACIDIFICATION; ALKALINIZATION; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL NUCLEUS; CELL PH; CELL POPULATION; CELL PROTECTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVITY; ENZYME DEGRADATION; INHIBITION KINETICS; IRON TRANSPORT; LIVER CELL; MITOCHONDRION; MOLECULAR WEIGHT; NONHUMAN; OBSERVATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; UPREGULATION;

ANIMALS; APOPTOSIS; BENZO(A)PYRENE; BIOLOGICAL TRANSPORT; CELL LINE; G(M1) GANGLIOSIDE; IRON; LIPID PEROXIDATION; MITOCHONDRIA; PHOSPHORYLATION; PROTECTIVE AGENTS; RATS; REACTIVE OXYGEN SPECIES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33750014047     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2006.07.014     Document Type: Article

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