Detergents with different chemical properties induce variable degree of cytotoxicity and mRNA expression of lipid-metabolizing enzymes and differentiation markers in cultured keratinocytes

Toxicology in Vitro

Volumn 20, Issue 8, 2006, Pages 1387-1394

  Wei, Tianling ^a   Geijer, Sophia ^a   Lindberg, Magnus ^b   Berne, Berit ^a   Törmä, Hans ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b STOCKHOLM COUNTY COUNCIL   (Sweden)

Author keywords

Ceramide; Dermatitis; Filaggrin; Involucrin; Irritants; Lipids; Skin; Skin barrier; Surfactants; Transglutaminase

Indexed keywords

COCAMIDOPROPYL BETAINE; COCOGLUCOSIDE; DETERGENT; DODECYL SULFATE SODIUM; ENZYME; MESSENGER RNA; SODIUM COCOAMPHOACETATE; SODIUM LAURETH SULFATE; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CYTOTOXICITY; FATTY ACID SYNTHESIS; HUMAN; HUMAN CELL; KERATINOCYTE; LD 50; LIPOGENESIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION;

AZO COMPOUNDS; BIOLOGICAL MARKERS; CELL DEATH; CELL DIFFERENTIATION; CELLS, CULTURED; COLORING AGENTS; DETERGENTS; ENZYMES; FEMALE; HUMANS; INFLAMMATION MEDIATORS; KERATINOCYTES; LETHAL DOSE 50; LIPID METABOLISM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSGLUTAMINASES;

EID: 33749863068     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2006.06.002     Document Type: Article

References (20)

1. Benassi L., Bertazzoni G., and Seidenari S. In vitro testing of tensides employing monolayer cultures: a comparison with results of patch tests on human volunteers. Contact Dermatitis 40 (1999) 38-44
2. Brey N.L., and Fowler Jr. J.F. Relevance of positive patch-test reactions to cocamidopropyl betaine and amidoamine. Dermatitis 15 (2004) 7-9
3. Corsini E., Viviani B., Zancanella O., Lucchi L., Visioli F., Serrero G., Bartesaghi S., Galli C.L., and Marinovich M. Induction of adipose differentiation related protein and neutral lipid droplet accumulation in keratinocytes by skin irritants. Journal of Investigative Dermatology 121 (2003) 337-344
4. Ekanayake-Mudiyanselage S., Aschauer H., Schmook F.P., Jensen J.M., Meingassner J.G., and Proksch E. Expression of epidermal keratins and the cornified envelope protein involucrin is influenced by permeability barrier disruption. Journal of Investigative Dermatology 111 (1998) 517-523
5. Farrell A.M., Uchida Y., Nagiec M.M., Harris I.R., Dickson R.C., Elias P.M., and Holleran W.M. UVB irradiation up-regulates serine palmitoyltransferase in cultured human keratinocytes. Journal of Lipid Research 39 (1998) 2031-2038
6. Gerritsen M.J., van Erp P.E., van Vlijmen-Willems I.M., Lenders L.T., and van de Kerkhof P.C. Repeated tape stripping of normal skin: a histological assessment and comparison with events seen in psoriasis. Archives of Dermatological Research 286 (1994) 455-461
7. Harris I.R., Farrell A.M., Grunfeld C., Holleran W.M., Elias P.M., and Feingold K.R. Permeability barrier disruption coordinately regulates mRNA levels for key enzymes of cholesterol, fatty acid, and ceramide synthesis in the epidermis. Journal of Investigative Dermatology 109 (1997) 783-787
8. Kucharekova M., Schalkwijk J., Van De Kerkhof P.C., and Van De Valk P.G. Effect of a lipid-rich emollient containing ceramide 3 in experimentally induced skin barrier dysfunction. Contact Dermatitis 46 (2002) 331-338
9. Le M., Schalkwijk J., Siegenthaler G., van de Kerkhof P.C., Veerkamp J.H., and van der Valk P.G. Changes in keratinocyte differentiation following mild irritation by sodium dodecyl sulphate. Archives of Dermatological Research 288 (1996) 684-690
10. Löffler H., and Happle R. Profile of irritant patch testing with detergents: sodium lauryl sulfate, sodium laureth sulfate and alkyl polyglucoside. Contact Dermatitis 48 (2003) 26-32
11. Nicander I., Rantanen I., Rozell B.L., Soderling E., and Ollmar S. The ability of betaine to reduce the irritating effects of detergents assessed visually, histologically and by bioengineering methods. Skin Research and Technology 9 (2003) 50-58
12. Norlén L. Skin barrier structure and function: the single gel phase model. Journal of Investigative Dermatology 117 (2001) 830-836
13. Pilgram G., and Bouwstra J. Stratum corneum lipid organization in vitro and in vivo as assessed by diffraction methods. In: Forslind B., and Lindberg M. (Eds). Skin, Hair and Nails. Structure and Function (2004), Marcel & Dekker, New York 107-152
14. Proksch E., Feingold K.R., and Elias P.M. Epidermal HMG CoA reductase activity in essential fatty acid deficiency: barrier requirements rather than eicosanoid generation regulate cholesterol synthesis. Journal of Investigative Dermatology 99 (1992) 216-220
15. Proksch E., Holleran W.M., Menon G.K., Elias P.M., and Feingold K.R. Barrier function regulates epidermal lipid and DNA synthesis. British Journal of Dermatology 128 (1993) 473-482
16. Santucci B., Cannistraci C., Lesnoni I., Ferraro C., Rocco M.G., Dell'Anna L., Giannarelli D., and Cristaudo A. Cutaneous response to irritants. Contact Dermatitis 48 (2003) 69-73
17. Stachowitz S., Alessandrini F., Abeck D., Ring J., and Behrendt H. Permeability barrier disruption increases the level of serine palmitoyltransferase in human epidermis. Journal of Investigative Dermatology 119 (2002) 1048-1052
18. Törmä H., Geijer S., Gester T., Alpholm K., Berne B., and Lindberg M. Variations in the mRNA expression of inflammatory mediators, markers of differentiation and lipid-metabolizing enzymes caused by sodium lauryl sulphate in cultured human keratinocytes. Toxicology In Vitro 20 (2006) 472-479
19. Wertz P., and Norlén L. "Confidence intervals" for the true" lipid composition of the human skin barrier?. In: Forslind B., and Lindberg M. (Eds). Skin, Hair and Nails. Structure and Function (2004), Marcel & Dekker, New York 85-106
20. Willis C., and Lindberg M. Understanding the irritant reaction. In: Forslind B., and Lindberg M. (Eds). Skin, Hair and Nails. Structure and Function (2004), Marcel & Dekker, New York 233-272