Induction of adipose differentiation related protein and neutral lipid droplet accumulation in keratinocytes by skin irritants

Journal of Investigative Dermatology

Volumn 121, Issue 2, 2003, Pages 337-344

  Corsini, Emmanuela ^a,c   Viviani, Barbara ^a   Zancanella, Omar ^a   Lucchi, Laura ^a   Visioli, Francesco ^a   Serrero, Ginette ^b   Bartesaghi, Stefano ^a   Galli, Corrado L ^a   Marinovich, Marina ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^c Laboratory of Toxicology   (Italy)

Author keywords

Cytotoxicity; Keratinocytes; Lipid droplets; Skin irritation; Triacylglycerol

Indexed keywords

ADIPOPHILIN; ANTISENSE OLIGONUCLEOTIDE; CHELATING AGENT; DODECYL SULFATE SODIUM; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ARTICLE; BIOGENESIS; CELL DIFFERENTIATION; CELLULAR DISTRIBUTION; CONTACT DERMATITIS; CYTOTOXICITY; HUMAN; HUMAN CELL; KERATINOCYTE; LIPID METABOLISM; LIPID STORAGE; LIPOGENESIS; MOLECULAR CLONING; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SKIN IRRITATION;

EID: 0041903684     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2003.12371.x     Document Type: Article

References (37)

1. Berardesca E, Distante F: The modulation of skin irritation. Contact Dermatisis 31:281-287, 1994
2. Bernini F, Canavesi M, Bernardini E, Scurati N, Bellosta S, Fumagalli R: Effect of lacidipine on cholesterol esterification: In vivo and in vitro studies. Br J Pharmacol 122:1209-1213, 1997
3. Boss JD, Kapsenberger ML: The skin immune system: Progress in cutaneous biology. Immunol Today 14:75-78, 1993
4. Brasaemle DL, Barber T, Wolins NE, Serrero G, Blanchette-Mackie EJ, Londons C: Adipose differentiation related protein is a ubiquitously expressed lipid storage droplet-associated protein. J Lipid Res 38:2249-2263, 1997
5. Brown DA: Lipid droplets: Proteins floating on a pool of fat. Current Biol 11:R446-R449, 2001
6. Chen JS, Greenberg AS, Tseng YZ, Wang SM: Possible involvement of protein kinase C in the induction of adipose differentiation related protein by sterol ester in RAW 264.7 macrophages. J Cellular Biochem 83:187-199, 2001
7. Corsini E, Galli CL: Cytokines and irritant contact dermatitis. Toxicol Lett 102-103:227-282, 1998
8. Corsini E, Galli CL: Epidermal cytokine in experimental contact dermatitis. Toxicol 142:203-211, 2000
9. Corsini E, Terzoli A, Bruccoleri A, Marinovich M, Galli CL: Induction of tumor necrosis factor-α in vivo by a skin irritant, tributyltin, through activation of transcription factors: Its pharmacological modulation by anti-inflammatory drugs. J Invest Dermatol 108:892-896, 1997a
10. Corsini E, Viviani B, Marinovich M, Galli CL: Role of mitochondria and calcium ions in tributyltin-induced gent regulatory pathways. Toxicol Appl Pharmacol 145:74-81, 1997b
11. Corsini E, Limiroli E, Marinovich M, Cohen C, Roguet R, Galli CL: Selective induction of interleukin 12 in reconstituted human epidermis by chemical allergens. ATLA 27:261-269, 1999
12. Corsini E, Viviani B, Marinovich M, Galli CL: Cyclosporin A exacerbates skin irritation induced by tributyltin by increasing nuclear factor κb activation. J Invest Dermatol 117:1627-1634, 2001
13. Corsini E, Sheasgreen J, Marinovich M, Galli CL: Use of differential display-polymerase chain reaction to identify genes selectively modulated by chemical allergens in reconstituted human epidermis. Toxicol Vitro 16:427-431, 2002
14. De La Llera M, Rothblat G, Howard BV: Cell triacylglycerol accumulation from very low density lipoproteins isolated from normal and hypertriglyceridemic human sera. Biochim Biophys Acta 574:414-422, 1979
15. Eisinger DP, Serrero G: Structure of the gene encoding mouse adipose differentiation-related protein (ADRP). Genomics 16:638-644, 1993
16. Elias PM: Lipids and the epidermal permeability barrier. Arch Dermatol Res 270:95-117, 1981
17. El-Shoura SM, Tallab TM: Richner-Hanhart's syndrome: New ultrastructural observation on skin lesions of two cases. Ultrastruct Pathol 21:51-56, 1997
18. Feldman D, Bryce GF, Shapiro SS: Ultrastructural effects of UVB radiation and subsequent retinoic acid treatment on the skin of hairless mice. J Cutan Pathol 18:46-55, 1991
19. Folch J, Lees M, Sloane Stanley GH: A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226:497-509, 1957
20. Greenspan P, Mayer EP, Fowler SD: Nile Red: A selective fluorescent stain for intracellular lipid droplets. J Cell Biol 100:965-973, 1985
21. Grubauer G, Feingold KR, Harris RM, Elias PM: Lipid content and lipid type as determinants of the epidermal permeability barrier. J Lipid Res 30:89-96, 1989
22. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450, 1985
23. Hansen AE, Knott EM, Weise HF, et al: Eczema and essential fatty acids. Am J Dis Child 73:1-18, 1987
24. Heid HW, Moll R, Schwetlick I, Rackwitz HR, Keenan TW: Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases. Cell Tissue Res 294:309-321, 1998
25. Holleran WM, Feingold KR, Mao-Qiang M, et al: Regulation of epidermal sphingolipid synthesis by permeability barrier function. J Lipid Res 32:1151-1158, 1991
26. Imokawa G, Akasaki S, Minematsu Y, Kawai M: Importance of intercellular lipids in water retention properties of the stratum corneum: Induction and recovery study of surfactant dry skin. Arch Dermatol Res 281:45-51, 1989
27. Jiang HP, Serrero G: Isolation and characterization of a full length cDNA coding for an adipose differentiation-related protein. Proc Natl Acad Sci USA 89:7856-7860, 1992
28. Johnson BL, Kramer EM, Lavker RM: The keratotic tumor of Cowden's disease: An electron microscopy study. J Cutan Pathol 14:291-298, 1987
29. Kanerva L: Electron microscopy of the effects of dithranol on healthy and on psoriatic skin. Am J Dermatopathol 12:51-62, 1990
30. Levin CY, Maibach HI: Irritant contact dermatiti: Is there an immunological component? Internatl Immunopharmacol 2:183-189, 2002
31. Linsby S, Baadsgard O: Mechanisms of irritant contact dermatitiss. In: Rycroft RJG, Menne T, Frosh PJ, Lepoittevin JP, (eds). Contact Dermatitis, 3rd edn. Berlin: Springer Verlag, 2001; p 93-104
32. Londos C, Brasaemle DL, Schultz CJ, Segrest JP, Kimmel AR: Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells. Cell Dev Biol 10:51-58, 1999
33. Mckenzie RC, Sauder DN: The role of keratinocyte cytokines in inflammation and immunity. J Invest Dermatol 95:1055-1075, 1990
34. Menon GK, Feingold KR, Moser AH, et al: De novo sterologenesis in the skin. II. Regulation by cutaneous barrier requirements. J Lipid Res 26:418-427, 1985
35. Miura S, Gan JW, Brzostowski J, Parisi MJ, Schultz CJ, Oliver B, Kimmel AR: Functional conservation for lipid storage droplet association among perilipin-, ADRP-, and TIP 47-related proteins in mammals, drosophila, and dictylostelium. J Biol Chem 277:32253-32257, 2002
36. Smith HR, Basketter DA, Mcfadden JP: Irritant dermatitis, irritancy and its role in allergic contact dermatitis. Clin Exp Dermatol 27:138-146, 2002
37. Williams ML, Menon GK, Hanley KP: HGM-CoA reductase inhibitors perturb fatty acid metabolism and induce peroxisomes in keratinocytes. J Lipid Ras 33:193-208, 1992