Estradiol coupling to human monocyte nitric oxide release is dependent on intracellular calcium transients: Evidence for an estrogen surface receptor

Journal of Immunology

Volumn 163, Issue 7, 1999, Pages 3758-3763

  Stefano, George B ^a,b,f   Prevot, Vincent ^c   Beauvillain, Jean Claude ^c   Fimiani, Caterina ^a,b   Welters, Ingeborg ^a,b   Cadet, Patrick ^a   Breton, Christophe ^d   Pestel, Joel ^e   Salzet, Michel ^a,b,d   Bilfinger, Thomas V ^a,b,f  

^a STATE UNIVERSITY OF NEW YORK   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c INSERM   (France)

^d CNRS   (France)

^e INSTITUT PASTEUR DE LILLE   (France)

^f STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; ESTRADIOL; ESTROGEN RECEPTOR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; TAMOXIFEN;

ARTICLE; CALCIUM CELL LEVEL; CELL ADHESION; ESTROGEN ACTIVITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MICROFLUOROMETRY; MONOCYTE; PHAGOCYTOSIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0033214424     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.163.7.3758     Document Type: Article

References (63)

1. Wessendorf, G., P. Scheibl, and P. S. Zerbe. 1998. Effect of estrogens on the immune system with regard to bovine placental retention. DTW (Dtsch. Tierarztl. Wochenschr.) 105:32.
2. Okada, M., A. Suzuki, K. Mizuno, Y. Asada, Y. Ino, T. Kuwayama, K. Tamakoshi, S. Mizutani, and Y. Tomoda. 1997. Effects of 17 β-estradiol and progesterone on migration of human monocytic THP-1 cells stimulated by minimally oxidized low-density lipoprotein in vitro. Cardiovasc. Res, 34:529.
3. Nathan, L., and G. Chaudhuri. 1997. Estrogens and atherosclerosis. Annu. Rev. Pharmacol. Toxicol. 37:477.
4. Miyagi, M., H. Aoyama, M. Morishita, and Y. Iwamoto. 1992. Effects of sex hormones on chemotaxis of human peripheral polymorphonuclear leukocytes and monocytes. J. Periodontol. 63:28.
5. Garzetti, G. G., A. Ciavattini, M. Provinciali, M. Amati, M. Muzzioli, and M. Governa. 1998. Decrease in peripheral blood polymorphonuclear leukocyte chemotactic index in endometriosis: role of prostaglandin E2 release. Obstet. Gynecol. 91:25.
6. Ito, I., T. Hayashi, K. Yamada, M. Kuzuya, M. Naito, and A. Iguchi. 1995. Physiological concentration of estradiol inhibits polymorphonuclear leukocyte chemotaxis via a receptor mediated system. Life Sci. 56:2247.
7. Murphy, S., M. L. Simmons, L. Agullo, A. Garcia, D. Feinstein, E. Galea, D. J. Reis, D. Minc-Golomb, and J. P. Schwartz. 1993. Synthesis of nitric oxide in CNS glial cells. Trends Neurosci 16:323.
8. Boulanger, C., and T. F. Luscher. 1990. Release of endothelin from the porcine aorta-inhibition by endothelium-derived nitric acid. J. Clin. Invest. 85:587.
9. Mefford, I. N., C. F. Masters, M. P. Heyes, and R. L. Eskay. 1991. Cytokine-induced activation of the neuroendocrine stress axis persists in endotoxin-tolerant mice. Brain Res. 557:327.
10. Merrill, J., Y. Koyanagi, and I. Chen. 1989. Interleukin I and tumor necrosis factor α can be induced from mononuclear phagocytes by HIV-1 binding to CD4 receptor. J. Virol. 63:4404.
11. Magnusson, U. 1991. In vitro effects of prepartum concentrations of oestradiol-17 β on cell-mediated immunity and phagocytosis by porcine leukocytes. Vet. Immunol. Immunopathol. 28:117.
12. al-Afaleq, A. I., and A. M. Homeida. 1998. Effects of low doses of oestradiol, testosterone and dihydrotestosterone on the immune response of broiler chicks. Immunopharmacol. Immunotoxicol. 20:315.
13. Masana, M. T., M. P. Heyes, and I. N. Mefford. 1990. Indomethacin prevents increased catecholamine turn over in rat brain fallowing systemic endotoxin challenge. Prog. Neuropsychopharmacol. Biol. Psychiatry 14:609.
14. Suzuki, A., K. Mizuno, Y. Asada, Y. Ino, T. Kuwayama, M. Okada, S. Mizutani, and Y. Tomoda. 1997. Effects of 17β-estradiol and progesterone on the adhesion of human monocytic THP-1 cells to human female endothelial cells exposed to minimally oxidized LDL. Gynecol. Obstet. Invest. 44:47.
15. Yamada, K., T. Hayashi, M. Kuzuya, M. Naito, K. Asai, and A. Iguchi. 1996. Physiological concentration of 17 β-estradiol inhibits chemotaxis of human monocytes in response to monocyte chemotactic protein 1. Artery 22:24.
16. Squadrito, F., D. Altavilla, G. Squadrito, G. M. Campo, M. Arlotta, V. Arcoraci, L. Minutoli, M. Serrano, A. Saitta, and A. P. Caputi. 1997. 17β-oestradiol reduces cardiac leukocyte accumulation in myocardial ischaemia reperfusion injury in rat. Eur. J. Pharmacol. 335:185.
17. Weissman, D., G. Poli, and A. S. Fauci. 1995. IL-10 synergizes with multiple cytokines in enhancing HIV production in cells of monocytic lineage. J. Acquired Immune Defic. Syndr. Hum. Retrovirol. 9:442.
18. Saville, M. W., K. Taga, A. Foli, S. Broder, G. Tosato, and R. Yarchoan. 1994. Interleukin-10 suppresses human immunodeficiency virus-1 replication in vitro in cells of the monocyte/macrophage lineage. Blood 83:3591.
19. Mohankumar, P. S., S. Thyagarajan, and S. K. Quadri. 1991. Interleukin-1 stimulates the release of dopamine and dihydroxyphenylacetic acid from the hypothalamus in vivo. Life Sci. 48:925.
20. Suenaga, R., M. J. Evans, K. Mitamura, V. Rider, and N. I. Abdou. 1998. Peripheral blood T cells and monocytes and B cell lines derived from patients with lupus express estrogen receptor transcripts similar to those of normal cells. J. Rheumatol. 25:1305.
21. Suenaga, R., K. Mitamura, M. J. Evans, and N. I. Abdou. 1996. Binding affinity and quantity of estrogen receptor in peripheral blood monocytes of patients with systemic lupus erythematosus. Lupus 5:227.
22. White, M., S. Zamudio, T. Stevens, R. Tyler, J. Lindenfeld, K. Leslie, and L. G. Moore. 1995. Estrogen, progesterone, and vascular reactivity: potential cellular mechanisms. Endocrine Rev. 16:739.
23. Ben-Hur, H., G. Mor, V. Insler, I. Blickstein, Y. Amir-Zaltsman, A. Sharp, A. Globerson, and F. Kohen. 1995. Menopause is associated with a significant increase in blood monocyte number and a relative decrease in the expression of estrogen receptors in human peripheral monocytes. Am. J. Reprod. Immunol. 34:363.
24. Wada, K., T. Itoh, M. Nakagawa, R. Misao, H. Mori, and T. Tamaya. 1992. Estrogen binding sites in peripheral blood monocytes and effects of danazol on their sites in vitro. Gen. Pharmacol. 23:693.
25. Bassenge, E. 1996. Endothelial function in different organs. Prog. Cardiovasc. Dis. 39:209.
26. Magazine, H. I., Y. Liu, T. V. Bilfinger, G. L. Fricchione, and G. B. Stefano. 1996. Morphine-induced conformational changes in human monocytes, granulocytes, and endothelial cells and in invertebrate immunocytes and microglia are mediated by nitric oxide. J. Immunol. 156:4845.
27. Stefano, G. B., A. Digenis, S. Spector, M. K. Leung, T. V. Bilfinger, M. H. Makman, B. Scharrer, and N. N. Abumrad. 1993. Opiatelike substances in an invertebrate, a novel opiate receptor on invertebrate and human immunocytes, and a role in immunosuppression. Proc. Natl. Acad. Sci. USA 90:11099.
28. Stefano, G. B., P. Melchiorri, L. Negri, T. K. Hughes, and B. Scharrer. 1992. (D-Ala2)-Deltorphin I binding and pharmacological evidence for a special subtype of delta opioid receptor on human and invertebrate immune cells. Proc. Natl. Acad. Sci. USA 89:9316.
29. Stefano, G. B., A. Hartman, T. V. Bilfinger, H. I. Magazine, Y. Liu, F. Casares, and M. S. Goligorsky. 1995. Presence of the mu3 opiate receptor in endothelial cells: coupling to nitric oxide production and vasodilation. J. Biol. Chem. 270: 30290.
30. Liu, Z., S. M. Wildhirt, S. Weismuller, C. Schulze, N. Conrad, and B. Reichart. 1998. Nitric oxide and endothelin in the development of cardiac allograft vasculopathy. Potential targets for therapeutic interventions. Atherosclerosis 140:1.
31. Fimiani, C., D. W. Mattocks, F. Cavani, M. Salzet, D. G. Deutsch, S. C. Pryor, T. V. Bilfinger, and G. B. Stefano. 1999. Morphine and anandamide stimulate intracellular calcium transients in human arterial endothelial endothelial cells: coupling to nitric oxide release. Cell. Signalling. 11:189.
32. Baffy, G., L. J. Yang, G. K. Michalopoulos, and J. R. Williamson. 1992. Hepatocyte growth factor induces calcium mobilization and inositol phosphate production in rat hepatocytes. J. Cell. Physiol. 153:332.
33. Loeb, A. L., D. E. Longnecker, and J. R. Williamson. 1993. Alteration of calcium mobilization in endothelial cells by volatile anesthetics. Biochem. Pharmacol. 45:1137.
34. Breton, C., C. Pechoux, G. Morel, and H. H. Zingg. 1995. Oxytocin receptor messenger ribonucleic acid: characterization, regulation, and cellular localization in the rat pituitary gland. Endocrinology 136:2928.
35. Green, S., P. Walter, V. Kumar, A. Krust, J. M. Bornert, P. Argos, and P. Chambon. 1986. Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature 320:134.
36. Mosselman, S., J. Polman, and R. Dijkema. 1996. ER β: identification and characterization of a novel human estrogen receptor. FEBS Lett. 392:49.
37. Scheidegger, C., and W. Zimmerli. 1989. Infectious complications in drug addicts: seven year review of 269 hospitalized narcotic abusers in Switzerland. Rev. Infect. Dis. 3:486.
38. Allen, R. W., K. A. Trach, and J. A. Hoch. 1987. Identification of the 37-kDa protein displaying a variable interaction with the erythoid cell membrane as glyceraldehyde-3-phosphate dehydrogenase. J. Biol. Chem. 262:649.
39. Hayashi, T., K. Yamada, T. Esaki, M. Kuzuya, S. Satake, T. Ishikawa, H. Hidaka, and A. Iguchi. 1995. Estrogen increases endothelial nitric oxide by a receptor-mediated system. Biochem. Biophys. Res. Commun. 214:847.
40. Lantin-Hermoso, R. L., C. R. Rosenfeld, I. S. Yuhanna, Z. German, Z. Chen, and P. W. Shaul. 1997. Estrogen acutely stimulates nitric oxide synthase activity in fetal pulmonary artery endothelium. Am. J. Physiol. 273:L119.
41. Stefano, G. B., V. Prevot, J. C. Beauvillain, T. V. Bilfinger, C. Fimiani, I. Welters, and G. L. Fricchione. 1999. Acute exposure of estrogen to human endothelia results in nitric oxide release mediated by an estrogen surface receptor coupled to intracellular calcium transients. Circulation. In press.
42. Guetta, V., A. A. Quyyumi, A. Prasad, J. A. Panza, M. Waclawiw, and R. O. Cannon. 1997. The role of nitric oxide in coronary vascular effects of estrogen in postmenopausal women. Circulation 96:2795.
43. Reis, S. E., S. T. Gloth, R. S. Blumenthal, J. R. Resar, H. A. Zacur, G. Gerstenblith, and J. A. Brinker. 1994. Ethinyl estradiol acutely attenuates abnormal coronary vasomotor responses to acetylcholine in postmenopausal women. Circulation 89:52.
44. Gilligan, D. M., D. M. Badar, J. A. Panza, A. A. Quyyumi, and I. R. O. Cannon. 1994. Effects of estrogen replacement therapy on peripheral vasomotor function in postmenopausal women. Am. J. Cordiol. 75:264.
45. Gilligan, D. M., D. M. Badar, J. A. Panza, A. A. Quyyumi, and R. O. Cannon. 1994. Acute vascular effects of estrogen in postmenopausal women. Circulation 90:786.
46. Gilligan, D. M., A. A. Quyyumi, and R. O. Cannon. 1994. Effects of physiological levels of estrogen on coronary vasomotor function in postmenopausal women. Circulation 89:2545.
47. Roque, M., M. Heras, E. Roig, M. Masotti, M. Rigol, A. Betriu, J. Balasch, and G. Sanz. 1998. Short-term effects of transdermal estrogen replacement therapy on coronary vascular reactivity in postmenopausal women with angina pectoris and normal results on coronary angiograms. J. Am. Coll. Cardiol. 31:139.
48. Chen, Z., I. S. Yuhanna, Z. Galcheva-Gargova, R. H. Karas, M. E. Mendelsohn, and P. W. Shaul. 1999. Estrogen receptor α mediates the nongenomic activation of endothlelial nitric oxide synthase by estrogen. J. Clin. Invest. 103:401.
49. Razandi, M., A. Pedram, G. L. Greene, and E. R. Levin. 1999. Cell membrane and nuclear receptors (ERs) originate from a single transcript: studies of ERα and ERβ expressed in Chinese hamster ovary cells. Mol. Endocrinol. 13:307.
50. Prevot, V., D. Croix, C. M. Rialas, P. Puolain, G. L. Fricchione, G. B. Stefano, and J. C. Beauvillain. 1999. Estradiol coupling to endothelial nitric oxide production stimulates GnRH release from rat median eminence. Endocrinology. 140:652.
51. Wong, M., and R. L. Moss. 1991. Electrophysiological evidence for a rapid membrane action of the gonadal steroid, 17-β-estradiol, on CA1 pyramidal neurons of the rat hippocampus. Brain Res. 543:148.
52. Drouva, S. V., E. Laplante, J. P. Gautron, and C. Kordon. 1984. Effects of 17 β-estradiol on LH-RH release from rat mediobasal hypothalamic slices. Neuroendocrinology 38:152.
53. Benten, W. P., M. Lieberherr, G. Giese, and F. Wunderlich. 1998. Estradiol binding to cell surface raises cytosolic free calcium in T cells. FEBS Lett. 422:349.
54. Node, K., M. Kitakaze, H. Kosaka, T. Minamino, H. Funaya, and M. Hori. 1997. Amelioration of ischemia- and reperfusion-induced myocardial injury by 17 β-estradiol: role of nitric oxide and calcium-activated potassium channels. Circulation 96:1953.
55. Lamping, K. G., and D. W. Nuno. 1996. Effects of 17 β-estradiol on coronary microvascular responses to endothelin-1. Am. J. Physiol. 271:1117.
56. Otter, D., and C. Austin. 1998. Effects of 17 β-estradiol on rat isolated coronary and mesenteric artery tone: involvement of nitric oxide. J. Pharm. Pharmacol. 50:531.
57. Miyahara, K., T. Kawamoto, K. Sase, Y. Yui, K. Toda, L. X. Yang, R. Hattori, T. Aoyama, Y. Yamamoto, and Y. Doi. 1994. Cloning and structural characterization of the human endothelial nitric-oxide-synthase gene. Eur. J. Biochem. 223:719.
58. Stefano, G. B., B. Scharrer, E. M. Smith, T. K. Hughes, H. I. Magazine, T. V. Bilfinger, A. Hartman, G. L. Fricchione, Y. Liu, and M. H. Makman 1996. Opioid and opiate immunoregulatory processes. Crit. Rev. Immunol. 16:109.
59. Stefano, G. B. 1998. Autoimmunovascular regulation: morphine and anandamide stimualted nitric oxide release. J. Neuroimmunol. 83:70.
60. Stefano, G. B., and B. Scharrer. 1994. Endogenous morphine and related opiates, a new class of chemical messengers. Adv. Neuroimmunol. 4:57.
61. Tonnesen, E., V. Brix-Christensen, T. V. Bilfinger, R. G. Sanchez, and G. B. Stefano. 1998. Endogenous morphine levels increase following cardiac surgery: Decreasing proinflammatory cytokine levels and immunocyte activity. J. Int. Cardiol. 62:191.
62. Fimiani, C., T. Liberty, A. J. Aquirre, I. Amir, N. Ali, and G. B. Stefano. 1999. Opiate, cannabinoid, and eicosanoid signaling converges on common intracellular pathways: nitric oxide coupling. Prostaglandins 57:23.
63. Service, R. F. 1998. New role for estrogen in cancer? Science 280:987.