The nano enterprise: A survey of health and safety concerns, considerations, and proposed improvement strategies to reduce potential adverse effects

Human Factors and Ergonomics In Manufacturing

Volumn 16, Issue 4, 2006, Pages 343-368

  Sequeira, Reynold ^a   Genaidy, Ash ^a   Shell, Richard ^a   Karwowski, Waldemar ^b   Weckman, Gary ^c   Salem, Sam ^a  

^a 705 Engineering Research Center   (United States)

^b University of Louisville   (United States)

^c US Institute of Navigation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENVIRONMENTAL HAZARDS; NANO ENTERPRISE; POTENTIAL ADVERSE EFFECTS;

ENVIRONMENTAL IMPACT; ENVIRONMENTAL PROTECTION; HAZARDOUS MATERIALS; HEALTH RISKS; NANOTECHNOLOGY;

HEALTH HAZARDS;

EID: 33749673741     PISSN: 10908471     EISSN: 15206564     Source Type: Journal    
DOI: 10.1002/hfm.20057     Document Type: Article

References (49)

1. AC/UNU MILLENNIUM PROJECT. (2004). Environmental pollution and health hazards resulting from military uses of nanotechnology Round 2. Retrieved Feb. 20, 2005, from http://www.acunu.org/millennium/ nanotech-rd2.html
2. Anissimov, M. (2004). More dangers from molecular nanotechnology. Centre for Responsible Nanotechnology. Retrieved between Feb. 15 and Mar. 15, 2005, from http://www.acceleratingfuture.com/michael/works/ nanotechdangers.htm
3. Arnall, A., & Douglass, P. (2005). Moving the nanoscience and technology debate forwards: Short term impacts, long term uncertainty and social constitution. Technology in Society, 27, 23-38.
4. Bradbury, R. (2003). Sapphire mansions. Retrieved between Feb. 15 and Mar. 15, 2005, from http://www.aeiveos.com/~bradbury/papers/sm.html
5. Colvin, V.L. (2003). The potential environmental impact of engineered nanomaterials. Nature Biotechnology, 21(10), 1166-1170.
6. Dekie, L., Toncheva, V., Dubruel, P., Schacht, E.H., Barrett, L., & Seymour, L.W. (2000). Poly-L-glutamic acid derivatives as vectors for gene therapy. Journal of Control Release, 65, 187-202.
7. Donaldson, K., Stone, V., Tran, C.L., Kreyling, W., & Borm, P.J.A. (2004). Nanotoxicology. Occupational and Environmental Medicine, 61, 727-728.
8. Dowling, A. (2004). Nanoscience and nanotechnologies: Opportunities and uncertainties - Summary and recommendations. London, UK: The Royal Society. Retrieved between Feb. 15 and Mar. 15, 2005, from http://www.nanotec.org.uk/finalReport.htm
9. Driscoll, K.E., Deyo, L.C., Carter, J.M., Howard, B.W., Hassenbein, D., & Bertram, T.A. (1997). Effects of particle exposure and particle-elicited inflammatory cells on mutation in rat alveolar epithelial cells. Carcinogenesis, 18(2), 423-430.
10. The Elsevier Foundation. (2002). Elsevier Science. Retrieved Feb. 15 to Mar. 15, 2005, from http://www.elsevier.com/wps/find/homepage.ews_home
11. Eyles, J.E., Bramwell, V.W., Williamsson, E.D., & Alpar, H.O. (2001). Microsphere trauslocation and immunopotentiation in systemic tissues following intranasal administration. Vaccine, 19, 4732-4742.
12. Fernandez-Urrusuno, R., Fattal, E., Feger, J., Couvreur, P., & Therond, P. (1997). Evaluation of hepatic antioxidant systems after intravenous administration of polymeric nanoparticles. Biomoterials, 18(6), 511-517.
13. Finch, G.L., Nikula, K.J., & Hoover, M.D. (1998). Dose response relationships between inhaled beryllium metal and lung toxicity in C3H mice. Toxicological Sciences, 42, 36-38.
14. Geiser, K. (2004). Nanotechnology and environmental and public health considerations, new solutions. New Solutions, 14(1), 9-18.
15. Genaidy, A.M., & Karwowski, W. (2006). The emerging field of health engineering. Theoretical Issues in Ergonomics Science, 7(2), 169-179.
16. Hett, A. (2004). Nanotechnology: Small matter, many unknowns. Zurich, Switzerland: Swiss Reinsurance Company. Retrieved between Feb. 15 and Mar. 15, 2005, from http://www.asse.org/ govupdate_02-3-05_nanosafety.pdf
17. Hoet, P.H.M., Brüske-Hohlfeld, I., & Salata, O.V. (2004). Nanoparticles - Known and unknown health risks. Journal of Nanobiotechnology, 2, 12, 1-15.
18. Huang, H., Meyer, K.C., Kubai, L., & Auerbach, R. (1992). An immune model of beryllium induced pulmonary granulomata in mice histology, immune reactivity, and flow cytometrie analysis of broncho alveolar lavage-derived cells. Laboratory investigation: A Journal of Technical Methods and Pathology, 67, 138-146.
19. Ingenta. (1998). Ingenta Connect. Retrieved Feb. 15 to Mar. 15, 2005, from http://www.ingenta.com
20. The Institute of Electrical and Electronics Engineers. (1963). IEEE. Retrieved between Feb. 15 and Mar. 15, 2005, from http://www.ieee.org/web/publications/home/index.html
21. Kawakami, K., Iwamura, A., Goto, E., Mori, Y., Abe, T., Hirasaw, Y., et al. (1990). Kinetics and clinical application of 99 mTc-techne gas. Kaku Igaku, 27, 725-733.
22. Keiper, A. (2003). The nanotechnology revolution. The new Atlantis, 2, 17-34.
23. Kreilgaard, M. (2002). Influence of microemulsions on cutaneous drug delivery. Advanced Drug Delivery Review, 54, 77-98.
24. Kulinowski, K. (2004). Nanotechnology: From "wow" to "yuck"? Technology and Society, 24(1), 13-20.
25. Lademann, J., Weigmann, H., Rickmeyer, C., Barthelmes, H., Schaefer, H., Mueller, G., et al. (1999). Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Applied Skin Physiology, 12, 247-256.
26. Lam, C.W., James, J.T., McCluskey, R., & Hunter, R.L. (2003). Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation. Toxicological Sciences, 77, 126-134.
27. Long, C.M. (2005). Nanotech: An overview. Cambridge, MA/Seattle, WA: Gradient Corporation. Retrieved Feb. 26, 2005, from http://www.gradientcorp.com/coinfo/pdf/Trends32.pdf
28. Lyman, J. (2003). Nanotech's green side: Cutting waste and risk, taming environmental fears. Small Times. Retrieved between Feb. 15 and Mar. 15, 2005, from http://www.smalltimes.com/ document_display.cfm?document_id=6783
29. Maynard, A.D., Baron, P.A., Foley, M., Shvedova, A.A., Kisin, E.R., & Castranova, V. (2004). Exposure to carbon nanotube material: Aerosol release during the handling of unrefined single walled carbon nanotube material. Journal of Toxicology and Environmental Health, 67, 87-107.
30. Michelson, E. (2004). Analyzing the European approach to nanotechnology. Washington, DC: Woodrow Wilson International Center for Scholars. Retrieved between Feb. 15 and Mar. 15, 2005, from http://www.environmentalfutures.org/Images/Nanotec1.pdf
31. Moore, F.N. (2002). Implications of nanotechnology applications: Using genetics as a lesson. Health Law Review, 10, 3, 9-15. Retrieved between Feb. 15 and Mar. 15, 2005, from http://www.law.ualberta.ca/centres/hli/ pdfs/hlr/v10_3/10.3moorefrm.pdf
32. National Institute for Occupational Health and Safety. (1971). NIOSHTIC-2. Retrieved between Feb. 15 and Mar. 15, 2005, from http://www2.cdc.gov/nioshtic-2/nioshticabout.htm
33. National Library of Medicine and National Institutes of Health. (1988). PubMed. Retrieved between Feb. 15 and Mar. 15, 2005, from http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB-pubmed
34. Nemmar, A., Hoylaerts, M.F., Hoet, P.H., Dinsdale, D., Smith, T., Xu, H., et al. (2002). Ultrafine particles affect experimental thrombosis in an in vivo hamster model. American Journal of Respiratory and Critical Care Medicine, 166(7), 998-1004.
35. Nemmar, A., Hoylaerts, M.F., Hoet, P.H., Vermylen, J., & Nemery, B. (2003). Size effect of intratracheally instilled particles on pulmonary inflammation and vascular thrombosis. Toxicology and Applied Pharmacology, 186(1), 38-45.
36. Oberdorster, G., Sharp, Z., & Atudorei, V. (2004). Translocation of inhaled ultrafine particles to the brain. Inhalation Toxicology, 16, 437-445.
37. Oberdorster, G., Sharp, Z., Atudorei, V., Elder, A., Gelein, R., Lunts, A., et al. (2002). Extrapulmonary translocation of ultrafine carbon particle following whole-body inhalation exposure of rats. Journal of Toxicology and Environmental Health, 65, 1531-1543.
38. Renwick, L.C., Brown, D., Clouter, A., & Donaldson, K. (2004). Increased inflammation and altered macrophage chemotactic responses caused by two ultrafine particle types. Occupational and Environmental Medicine, 61, 442-447
39. Roco, M.C., & Bainbridge, W. (2002). Converging technologies for improving human performance: Nanotechnology, biotechnology, information technology and cognitive science. National Science Foundation and the Department of Commerce Report. Arlington, VA: World Technologies Evaluation center, Inc. Retrieved between Feb. 15 and Mar. 15, 2005, from http://www.wtec.org/ConvergingTechnologies/Report/NBIC_report.pdf
40. Service, R.F. (2004). Nanotechnology grows up. News Focus SCIENCE, 304, 1732-1734. Retrieved between Feb. 15 and Mar. 15, 2005, from www.sciencemag.org, http://www.rifters.com/real/articles/ nanotecho_grows_up.pdf
41. Shvedova, A.A., Castranova, V., & Kisin, E. (2003). Exposure to carbon nanotube material: Assessment of nanotube cytotoxicity using human keratinocyte cells. Journal of Toxicology and Environmental Health, 66, 1909-1926.
42. Szentkuti, L. (1997). Light microscopical observations on luminally administered dyes. dextrans, nanospheres and microspheres in the pre-epithelial mucus gel layer of the rat distal colon. Journal of Control Release, 46, 233-242.
43. Tinkle, S.S., Antonini, J.M., Rich, B.A., Roberts, J.R., Salmen, R., DePree, K., et al. (2003). Skin as a route of exposure and sensitization in chronic beryllium disease. Environmental Health Perspective, 111, 1202-1208.
44. Wardak, A. (2003). Nanotechnology & regulation: A case study using the TSCA. Washington, DC: Woodrow Wilson International Centre for Scholars. Retrieved between Feb. 15 and Mar. 15, 2005, from http://www.environmentalfutures.org/nanotsca_final2.pdf
45. Warheit, D.B. (2004). Nanoparticles health impacts. Materials Today. Retrieved between Feb. 15 and Mar. 15, 2005, from http://www.materialstoday.com/pdfs_7_2/warheit.pdf
46. Warheit, D.B., Laurence, B.R., Reed, K.L., Roach, D.H., Reynolds, G.A., & Webb, T.R. (2003). Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats. Toxicological Sciences, 77(1), 117-125.
47. Weiss, R. (2004a). For science, nanotech poses big unknowns. Washington Post. Retrieved between Feb. 15 and Mar. 15, 2005, from http://www.washingtonpost.com/ac2/wp-dyn?pagename=article&node= &contentId=A1487-2004Jan31¬Found=true
48. Weiss, R. (2004b). Nanotechnology linked to organ damage-study. Washington Post. Retrieved between Feb. 15 and Mar. 15, 2005, from http://www.mindfully.org/Technology/2004/Nanotech-Organ-Damage29mar04.htm
49. Wolfgang, L. (2004). Industrial applications of nanomaterials: Chances and risks - Technological analysis. Dusseldorf, Germany: VDI Technologiezentrum GmbH. Retrieved between Feb. 15 and Mar. 15, 2005, from http://www.nano.sdu.dk/pdf/nanosafe.pdf