Synthesis of oxysterols and nitrogenous sterols with antileishmanial and trypanocidal activities

European Journal of Medicinal Chemistry

Volumn 41, Issue 10, 2006, Pages 1109-1116

  Bazin, Marc Antoine ^a   Loiseau, Philippe M ^b   Bories, Christian ^b   Letourneux, Yves ^c   Rault, Sylvain ^a   El Kihel, Laïla ^a  

^a CENTRE D ETUDES ET DE RECHERCHE SUR LE MÉDICAMENT DE NORMANDIE   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c AIX MARSEILLE UNIVERSITY   (France)

Author keywords

Antileishmanial; Nitrogenous sterols; Oxysterols; Trypanocidal

Indexed keywords

16,26 DIHYDROXYCHOLESTEROL; 22 OXOCHOLESTEROL; 24 HYDROXY 24 METHYLCHOLESTEROL; 24 METHYLENECHOLESTEROL; 7ALPHA DICYANOMETHYLCHOLESTEROL; 7ALPHA,BETA AMINOCHOLESTEROL; 7BETA AMINOMETHYLCHOLESTEROL; 7BETA DICYANOMETHYLCHOLESTEROL; AMPHOTERICIN B; ANTILEISHMANIAL AGENT; HYDROXYSTEROL; KETOSTEROL; N HYDROXYIMINOCHOLESTEROL; OXYSTEROL; PENTAMIDINE; STEROL DERIVATIVE; UNCLASSIFIED DRUG; ANTIPROTOZOAL AGENT; ANTITRYPANOSOMAL AGENT; STEROID;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; LEISHMANIA DONOVANI; MACROPHAGE; NONHUMAN; PROMASTIGOTE; STEROL METABOLISM; TRYPANOSOMA BRUCEI; TRYPOMASTIGOTE; ANIMAL; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; CLASSIFICATION; DRUG EFFECT; DRUG SENSITIVITY; FEMALE; MOUSE; PARASITOLOGY; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; ANTIPROTOZOAL AGENTS; CELLS, CULTURED; FEMALE; LEISHMANIA DONOVANI; MACROPHAGES; MICE; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; STEREOISOMERISM; STEROIDS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI;

EID: 33749655167     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2006.03.033     Document Type: Article

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