Inhibition of Nav1.7 and Nav1.4 sodium channels by trifluoperazine involves the local anesthetic receptor

Journal of Neurophysiology

Volumn 96, Issue 4, 2006, Pages 1848-1859

  Sheets, Patrick L ^a   Gerner, Peter ^b   Wang, Chi Fei ^b   Wang, Sho Ya ^c   Ging, Kuo Wang ^b   Cummins, Theodore R ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALMODULIN; SODIUM CHANNEL; TRIFLUOPERAZINE; VOLTAGE GATED SODIUM CHANNEL; ANALGESIC AGENT; DRUG RECEPTOR; LOCAL ANESTHETIC AGENT; MUSCLE PROTEIN; NA(V)1.4 CHANNEL, HUMAN; SCN9A PROTEIN, HUMAN;

AMPLITUDE MODULATION; ANIMAL EXPERIMENT; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; FEMALE; HYPERPOLARIZATION; IN VIVO STUDY; LOCAL ANESTHESIA; MOTOR NERVE BLOCK; NERVE BLOCK; NOCICEPTION; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; RAT; SCIATIC NERVE; STEADY STATE; ACTION POTENTIAL; CELL LINE; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HUMAN; MUTATION; PATCH CLAMP; PHYSIOLOGY;

ACTION POTENTIALS; ANALGESICS; ANESTHETICS, LOCAL; CALMODULIN; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MUSCLE PROTEINS; MUTATION; PATCH-CLAMP TECHNIQUES; RECEPTORS, DRUG; SCIATIC NERVE; SODIUM CHANNELS; TRIFLUOPERAZINE;

EID: 33749519214     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00354.2006     Document Type: Article

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