Chunghyul-Dan (Qingxie-Dan) improves arterial stiffness in patients with increased baPWV

American Journal of Chinese Medicine

Volumn 34, Issue 4, 2006, Pages 553-563

  Park, Seong Uk ^a   Jung, Woo Sang ^a   Moon, Sang Kwan ^a   Ko, Chang Nam ^a   Cho, Ki Ho ^a   Kim, Young Suk ^a   Bae, Hyung Sup ^a  

^a Kyung Hee University   (South Korea)

Author keywords

Arterial stiffness; Chunghyul dan; Pulse wave velocity (PWV)

Indexed keywords

ANTILIPEMIC AGENT; CHOLESTEROL; CHUNGHYUL DAN; COPTIS JAPONICA EXTRACT; COPTIS RHIZOME; GARDENIA JASMINOIDES EXTRACT; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PHELLODENDRON AMURENSE EXTRACT; PLANT EXTRACT; QINGXIE DAN; RHUBARB EXTRACT; SCUTELLARIA BAICALENSIS EXTRACT; SCUTELLARIAE RADIX; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ABSENCE OF SIDE EFFECTS; ADULT; AGED; ANALYZER; ANKLE BRACHIAL INDEX; ANTIINFLAMMATORY ACTIVITY; ARTERIOSCLEROSIS; ARTICLE; ATHEROSCLEROSIS; BLOOD PRESSURE MEASUREMENT; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COPTIS; CORK TREE; DIASTOLIC BLOOD PRESSURE; DOSE RESPONSE; DRUG EFFICACY; FEMALE; GARDENIA; HUMAN; LIPID BLOOD LEVEL; MALE; PULSE PRESSURE; PULSE WAVE; RANDOMIZED CONTROLLED TRIAL; RHUBARB; SCUTELLARIA BAICALENSIS; STATISTICAL SIGNIFICANCE; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL;

AGED; ALANINE TRANSAMINASE; ANKLE; ARTERIOSCLEROSIS; ASPARTATE AMINOTRANSFERASES; BLOOD FLOW VELOCITY; BLOOD PRESSURE; BLOOD UREA NITROGEN; BRACHIAL ARTERY; CHOLESTEROL; CHOLESTEROL, HDL; CHOLESTEROL, LDL; CREATININE; DRUG ADMINISTRATION SCHEDULE; DRUGS, CHINESE HERBAL; FEMALE; HUMANS; MALE; MIDDLE AGED; PHYTOTHERAPY; PULSATILE FLOW; TREATMENT OUTCOME; TRIGLYCERIDES;

EID: 33749486871     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X06004090     Document Type: Article

References (46)

1. Arnett, D.K., L.L. Boland, G.W. Evans, W. Riley, R. Barnes, H.A. Tyroler and G. Heiss. Hypertension and arterial stiffness: The Atherosclerosis Risk in Communities Study. ARIC Investigators. Am. J. Hypertens. 13: 317-323, 2000.
2. Bank, A.J., H. Wang, J.E. Holte, K. Mullen, R. Shammas and S.H. Kubo. Contribution of collagen, elastin, and smooth muscle to in vivo human brachial artery wall stress and elastic modulus. Circulation 94: 3263-3270, 1996.
3. Benetos, A., M. Safar, A. Rudnichi, H. Smulyan, J.L. Richard, P. Ducimetieere and L. Guize. Pulse pressure: A predictor of long-term cardiovascular mortality in a French male population. Hypertension 30: 1410-1415, 1997.
4. Blacher, J., R. Asmar, S. Djane, G.M. London and M.E. Safar. Aortic pulse wave velocity as a marker of cardiovascular risk in hypertensive patients. Hypertension 33: 1111-1117, 1999.
5. Bots, M.L., J.M. Dijk, A. Oren and D.E. Grobbee. Carotid intima-media thickness, arterial stiffness and risk of cardiovascular disease: current evidence. J. Hypertens. 20: 2317-2325, 2002.
6. Breithaupt-Groegler K., M. Ling, H. Boudoulas and G.G. Belz. Protective effect of chronic garlic intake on elastic properties of aorta in the elderly. Circulation 96: 2649-2655, 1997.
7. Busse, R., A. Luckhoff and E. Bassenge. Endothelium-derived relaxant factor inhibits platelet activation. Naunyn. Schmiedebergs. Arch. Pharmacol. 336: 566-571, 1987.
8. Caputo, L., A. Tedgui and B.I. Levy. Control of carotid vasomotor tone by local renin-angiotensin system in normotensive and spontaneously hypertensive rats: Role of endothelium and flow. Circ. Res. 77: 303-309, 1995.
9. Cho, K.H., H.S. Kang, W.S. Jung, S.U. Park and S.K. Moon. Efficacy and safety of Chunghyul-dan (Qingwie-dan) in patients with hypercholesterolemia. Am. J. Chin. Med. 33: 241-248, 2005.
10. Cho, K.H., Y.S. Kim, H.S. Bae, S.K. Moon, W.S. Jung, E.K. Park and D.H. Kim. Inhibitory effect of Chunghyuldan in prostaglandin E2 and nitric oxide biosynthesis of lipopolysaccharide-induced RAW 264.7 cells. Biol. Pharm. Bull. 27(11): 1810-1813, 2004.
11. Cortez-Cooper, M.Y., J.A. Supak and H. Tanaka. A new device for automatic measurements of arterial stiffness and ankle-brachial index. Am. J. Cardiol. 91: 1519-1522, 2003.
12. Dart, A.M. and B.A. Kingwell. Pulse pressure: A review of mechanisms and clinical relevance. J. Am. Coll. Cardiol. 37: 975-984, 2001.
13. Fitch, R.M., R. Vergona, M.E. Sullivan and Y.X. Wang. Nitric oxide synthase inhibition increases aortic stiffness measured by pulse wave velocity in rats. Cardiovasc. Res. 51: 351-358, 2001.
14. Garg, U.C. and A. Hassid. Nitric oxide-generating vasodilators and 8-bromr-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J. Clin. Invest. 83: 1774-1777, 1989.
15. Hasegawa M., K. Nagao, Y. Kinoshita, D. Rodbard and A. Asahina. Increased pulse wave velocity and shortened pulse wave transmission time in hypertension and aging. Cardiology 88:147-151, 1997.
16. Hayakawa, J., N. Noda, S. Yamada, E. Mikami and K. Uno. Studies on physical chemical quality evaluation of crude drugs preparations. III. Analysis of gardenia fruits and its preparations. Yakugaku Zasshi 105: 996-1000, 1985.
17. Ito, A., K. Egashira, T. Kadokami, Y. Fukumoto, T. Takayanagi, R. Nakaike, T. Kuga, K. Sueishi, H. Shimokawa and A. Takeshita. Chronic inhibition of endothelium-derived nitric oxide synthesis causes coronary microvascular structural changes and hyperreactivity to serotonin in pigs. Circulation 92: 2636-2644, 1995.
18. Kelly, R., C. Hayward, A. Avolio and M. O'Rourke. Noninvasive determination of age-related changes in the human arterial pulse. Circulation 80: 1652-1659, 1989.
19. Kim, Y.S., E.A. Jung, J.E. Shin, J.C. Chung, H.K. Yang, N.J. Kim, K.H. Cho, H.S. Bae, S.K. Moon and D.H. Kim. Daio-Orengedokuto inhibits HMG-CoA reductase and pancreatic lipase. Biol. Pharm. Bull. 25: 1442-1445, 2002.
20. Kinlay, S., M.A. Creager, M. Fukumoto, H. Hikita, J.C. Fang, A.P. Selwyn. and P. Ganz. Endothelium-derived nitric oxide regulates arterial elasticity in human arteries in vivo. Hypertension 38: 1049-1053, 2001.
21. London, G.M. and J.N. Cohn. Prognostic application of arterial stiffness: Task force. Am. J. Hypertens. 15: 754-758, 2002.
22. McVeigh, G.E., P.K. Hamilton and D.R. Morgan. Evaluation of mechanical arterial properties: Clinical, experimental and therapeutic aspects. Clin. Sci. (Lond) 102: 51-67, 2002.
23. Mitchell, G.F. and M.A. Pfeffer. Pulsatile hemodynamics in hypertension. Curr. Opin. Cardiol. 14: 361-369, 1999.
24. Munakata, M., N. Ito, T. Nunokawa and K. Yoshinaga. Utility of automated brachial ankle pulse wave velocity measurements in hypertensive patients. Am. J. Hypertens. 16: 653-657, 2003.
25. Nakayama T., T. Hironaga, H. Ishima, T. Maruyama, Y. Masubuchi and S. Kokubun. The prostacyclin analogue beraprost sodium prevents development of arterial stiffness in elderly patients with cerebral infarction. Prostaglandins, Leukotrienes and Essential Fatty Acids 70: 491-494, 2004.
26. Numaguchi, K., K. Egashira, M. Takemoto, T. Kadokami, H. Shimokawa, K. Sueishi and A. Takeshita. Chronic inhibition of nitric oxide synthesis causes coronary microvascular remodeling in rats. Hypertension 26: 957-962, 1995.
27. O'Rourke, M.F. and G. Mancia. Arterial stiffness. J. Hypertens. 17: 1-4, 1999.
28. Park, S.U., W.S. Jung, S.K. Moon, C.N. Ko, K.H. Cho, Y.S. Kim, H.S. Bae and S.G. Chi. Chunghyuldan Activates NOS mRNA expression and suppresses VCAM-1 mRNA expression in human endothelial cells. Can. J. Physiol. Pharmacol., in press.
29. Ramsey, M.W., J. Goodfellow, C.J. Jones, L.A. Luddington, M.J. Lewis and A.H. Henderson. Endothelial control of arterial distensibility is impaired in chronic heart failure. Circulation 92: 3212-3219, 1995.
30. Safar, M.E., B.I. Levy and H. Struijiker-Boudier. Current perspectives on arterial stiffness and pulse pressure in hypertension and cardiovascular diseases. Circulation 107: 2864-2869, 2003.
31. Shyy, J.Y. and S. Chien. Role of integrins in endothelial mechanosensing of shear stress. Circ. Res. 91: 769-775, 2002.
32. Takemoto, M., K. Egashira, Y. Tsutsui, H. Shimokawa, A. Takeshita and K. Sueishi. Vascular remodeling and nitric oxide. Rinsho. Byori. Suppl: 216-223, 1997.
33. Taniwaki, H., T. Kawagishi, M. Emoto, T. Shoji, H. Kanda, K. Maekawa, Y. Nishizawa and H. Morii. Correlation between the intima-media thickness of the carotid artery and aortic pulse-wave velocity in patients with type 2 diabetes. Vessel wall properties in type 2 diabetes. Diabetes Care 22: 1851-1857, 1999.
34. Terasawa, K. Diagnostic scoring system for Yin-Yang. Diagnostic scoring system for Excess-Deficiency. In: Kampo Japanese-Oriental Medicine Insights From Clinical Cases. Tokyo. K.K. Standard McIntyre. 1993, pp. 82-86.
35. van Popele, N.M., D.E. Grobbee, M.L. Bots, R. Asmar, J. Topouchian, R.S. Reneman, A.P. Hoeks, D.A. van der Kuip, A. Hofman and J.C. Witteman. Association between arterial stiffness and atherosclerosis: The Rotterdam Study. Stroke 32: 454-460, 2001.
36. Vanhoutte, P.M. and J. De Mey. Control of vascular smooth muscle function by the endotherial cells. Gen. Pharmacol. 14: 39-41, 1983.
37. Wang, Y.X. and R.M. Fitch. Vascular stiffness: Measurements, mechanisms and implications. Curr. Vas. Pharmacol. 2: 379-384, 2004.
38. Wang, Y.X., B. Martin-McNully, L.Y. Huw, V. da Cunha, J. Post, J. Hinchman, R. Vergona, M.E. Sullivan, W. Dole and K. Kauser. Anti-atherosclerotic effect of simbastatin depends on the presence of apolipoprtein E. Atherosclerosis 162: 23-31, 2002.
39. Wang, Y.X., M. Halks-Miller, R. Vergona, M.E. Sullivan, R. Fitch, C. Mallari, B. Martin-McNulty, V. da Cunha, A. Freay, G.M. Rubanyi and K. Kauser. Increased aortic stiffness assessed by pulse wave velocity in apolipoprotein E-deficient mice. Am. J. Physiol. Heart. Circ. Physiol. 278: H428-H434, 2000.
40. Watanabe I., S. Tani, T. Anazawa, T. Kushiro and K. Kanmatsuse. Effect of pioglitazone on arteriosclerosis in comparison with that of glibenclamide. Diabetes Research and Clinical Practice 68: 104-110, 2005.
41. Wilkinson, I.B., H. MacCallum, J.R. Cockcroft and D.J. Webb. Inhibition of basal nitric oxide synthesis increases aortic augmentation index and pulse wave velocity in vivo. Br. J. Clin. Pharmacol. 53: 189-192, 2002.
42. Wilkinson, I.B., J.R. Cockcroft and D.J. Webb. Pulse wave analysis and arterial stiffness. J. Cardiovasc. Pharmacol. 32: 33-37, 1999.
43. Yamashina, A., H. Tomiyama, K. Takeda, H. Tsuda, T. Arai, K. Hirose, Y. Koji, S. Hori and Y. Yamamoto. Validity, reproducibility, and clinical significance of noninvasive brachial-ankle pulse wave velocity measurement. Hypertens. Res. 25: 359-364, 2002.
44. Yamashina, A., H. Tomiyama, T. Arai, K. Hirose, Y. Koji, Y. Hirayama, Y. Yamamoto and S. Hori. Brachial-ankle pulse wave velocity as a marker of atherosclerotic vascular damage and cardiovascular risk. Hypertens. Res. 26: 615-622, 2003.
45. Yamashita, T., T. Sasahara, S.E. Pomeroy, G. Collier and P.J. Nestel. Arterial compliance, blood pressure, plasma leptin, and plasma lipids in women are improved with weight reduction equally with a meat based diet and a plant-based diet. Metabolism 47: 1308-1314, 1998.
46. Yokoyama, H., K. Hirasawa, T. Aoki, M. Ishiyama and K. Koyama. Brachial-ankle pulse wave velocity measured automatically by oscillometric method is elevated in diabetic patients with incipient nephropathy. Diabet. Med. 20: 942-945, 2003.