Use of a Stringent Dimerizer-Regulated Gene Expression System for Controlled BMP2 Delivery

Molecular Therapy

Volumn 14, Issue 5, 2006, Pages 684-691

  Koh, Jeong Tae ^a   Ge, Chunxi ^a   Zhao, Ming ^a   Wang, Zhuo ^b   Krebsbach, Paul H ^b   Zhao, Zhuoran ^a   Franceschi, Renny T ^a,c  

^a Center for Craniofacial Regeneration   (United States)

^b Temple University School of Medicine   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

BMP2; bone regeneration; gene therapy; inducible system; rapamycin; retrovirus

Indexed keywords

ADENOVIRUS VECTOR; BONE MORPHOGENETIC PROTEIN 2; RAPAMYCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE REGENERATION; CONTROLLED STUDY; DIMERIZATION; DRUG MECHANISM; GENE DELIVERY SYSTEM; GENE EXPRESSION REGULATION; GENE EXPRESSION SYSTEM; MOUSE; MOUSE STRAIN; NONHUMAN; NONVIRAL GENE THERAPY; OSSIFICATION; SKULL DEFECT; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEINS; CELLS, CULTURED; DIMERIZATION; GENE EXPRESSION REGULATION; MICE; OSTEOGENESIS; RATS; RECOMBINANT FUSION PROTEINS; SIROLIMUS; TRANSFORMING GROWTH FACTOR BETA;

EID: 33749446711     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2006.05.021     Document Type: Article

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