Human memory T cell responses to SARS-CoV E protein

Microbes and Infection

Volumn 8, Issue 9-10, 2006, Pages 2424-2431

  Peng, Hui ^a   Yang, Li tao ^a   Li, Jian ^b   Lu, Zhi qiang ^c   Wang, Ling yun ^c   Koup, Richard A ^d   Bailer, Robert T ^d   Wu, Chang you ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b GUANGDONG PROVINCIAL HOSPITAL OF CHINESE MEDICINE   (China)

^c SUN YAT SEN UNIVERSITY   (China)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

E protein; Epitope; Human; Memory T cells; SARS coronavirus

Indexed keywords

EPITOPE; STRUCTURAL PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS PROTEIN E2; VIRUS PROTEIN E5;

ADULT; AMINO ACID SEQUENCE; ANTIGEN EXPRESSION; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MALE; MEMORY T LYMPHOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SARS CORONAVIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; VIRUS VIRULENCE;

ADULT; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; EPITOPES, T-LYMPHOCYTE; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNODOMINANT EPITOPES; IMMUNOLOGIC MEMORY; INTERFERON TYPE II; INTERFERON-GAMMA; MALE; SARS VIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; T-LYMPHOCYTES; VIRAL ENVELOPE PROTEINS;

SARS CORONAVIRUS;

EID: 33749341878     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2006.05.008     Document Type: Article

References (35)

1. Peiris J.S.M., Lai S.T., Poon L.L.M., Guan Y., Yam L., Lim W., Nicholls J., Yee W., Yan W., Cheung M., Cheng V., Chan K., Tsang D., Yung R., Ng T., and Yuen K. Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet 361 (2003) 1319-1325
2. Ksiazek T.G., Erdman D., Goldsmith C.S., Zaki S.R., Peret T., Emery S., Tong S., Urbani C., Comer J.A., Lim W., Rollin P.E., Dowell S.F., Ling A.E., Humphrey C.D., Shieh W.J., Guarner J., Paddock C.D., Rota P., Fields B., DeRisi J., Yang J.Y., Cox N., Hughes J.M., LeDuc J.W., Bellini W.J., and Anderson L.J. A novel coronavirus associated with severe acute respiratory syndrome. New Engl. J. Med. 348 (2003) 1953-1966
3. Drosten C., Gunther S., Preiser W., Van der Werf S., Brodt H.R., Becker S., Rabenau H., Panning M., Kolesnikova L., Fouchier R.A., Berger A., Burguiere A.M., Cinatl J., Eickmann M., Escriou N., Grywna K., Kramme S., Manuguerra J.C., Muller S., Rickerts V., Sturmer M., Vieth S., Klenk H.D., Osterhaus A.D., Schmitz H., and Doerr H.W. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. New Engl. J. Med. 348 (2003) 1967-1976
4. Tsang K.W., Ho P.L., Ooi G.C., Yee W.K., Wang T., Chan-Yeung M., Lam W.K., Seto W.H., Yam L.Y., Cheung T.M., Wong P.C., Lam B., Ip M.S., Chan J., Yuen K.Y., and Lai K.N. A cluster of cases of severe acute respiratory syndrome in Hong Kong. New Engl. J. Med. 348 (2003) 1977-1985
5. Rota P.A., Oberste M.S., Monroe S.S., Nix W.A., Campagnoli R., Icenogle J.P., Penaranda S., Bankamp B., Maher K., Chen M.H., Tong S., Tamin A., Lowe L., Frace M., DeRisi J.L., Chen Q., Wang D., Erdman D.D., Peret T.C., Burns C., Ksiazek T.G., Rollin P.E., Sanchez A., Liffick S., Holloway B., Limor J., McCaustland K., Olsen-Rasmussen M., Fouchier R., Gunther S., Osterhaus A.D., Drosten C., Pallansch M.A., Anderson L.J., and Bellini W.J. Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science 300 (2003) 1394-1399
6. Marra M.A., Jones S.J., Astell C.R., Holt R.A., Brooks-Wilson A., Butterfield Y.S., Khattra J., Asano J.K., Barber S.A., Chan S.Y., Cloutier A., Coughlin S.M., Freeman D., Girn N., Griffith O.L., Leach S.R., Mayo M., McDonald H., Montgomery S.B., Pandoh P.K., Petrescu A.S., Robertson A.G., Schein J.E., Siddiqui A., Smailus D.E., Stott J.M., Yang G.S., Plummer F., Andonov A., Artsob H., Bastien N., Bernard K., Booth T.F., Bowness D., Czub M., Drebot M., Fernando L., Flick R., Garbutt M., Gray M., Grolla A., Jones S., Feldmann H., Meyers A., Kabani A., Li Y., Normand S., Stroher U., Tipples G.A., Tyler S., Vogrig R., Ward D., Watson B., Brunham R.C., Krajden M., Petric M., Skowronski D.M., Upton C., and Roper R.L. The Genome sequence of the SARS-associated coronavirus. Science 300 (2003) 1399-1404
7. Li W., Moore M.J., Vasilieva N., Sui J., Wong S.K., Berne M.A., Somasundaran M., Sullivan J.L., Luzuriaga K., Greenough T.C., Choe H., and Farzan M. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature 426 (2003) 450-454
8. Gu J., Gong E., Zhang B., Jie Z., Gao Z., Zhong Y., Zou W., Zhan J., Wang S., Xie Z., Zhuang H., Wu B., Zhong H., Shao H., Fang W., Gao D., Pei F., Li X., He Z., Xu D., Shi X., Anderson V.M., and Leong A.S.Y. Multiple organ infection and the pathogenesis of SARS. J. Exp. Med. 202 (2005) 415-424
9. Farcas G.A., Poutanen S.M., Mazzulli T., Willey B.M., Butany J., Asa S.L., Faure P., Akhavan P., Low D.E., and Kain K.C. Fatal Severe acute respiratory syndrome is associated with multiorgan involvement by coronavirus. J. Infect. Dis. 191 (2005) 193-197
10. Li G., Chen X., and Xu A. Profile of specific antibodies to the SARS associated coronavirus. New Engl. J. Med. 349 (2003) 508-509
11. Guo J.P., Petric M., Campbell W., and McGeer P.L. SARS coronavirus peptides recognized by antibodies in the sera of convalescent cases. Virology 324 (2004) 251-256
12. Tripp R.A., Haynes L.M., Moore D., Anderson B., Tamin A., Harcourt B.H., Jones L.P., Yilla M., Babcock G.J., Greenough T., Ambrosino D.M., Alvarez R., Callaway J., Cavitt S., Kamrud K., Alterson H., Smith J., Harcourt J.L., Miao C., Razdan R., Comer J.A., Rollin P.E., Ksiazek T.G., Sanchez A., Rota P.A., Bellini W.J., and Anderson L.J. Monoclonal antibodies to SARS-associated coronavirus (SARS-CoV): identification of neutralizing and antibodies reactive to S, N, M and E viral proteins. J. Virol. Methods 128 (2005) 21-28
13. +T-cell epitope SSp-1 of SARS-CoV spike protein. Blood 104 (2004) 200-206
14. Wang Y., Sin W.F., Xu G., Xu G., Yang H., Wong T., Pang X., He X., Zhang H., Ng J.N.L., Cheng C.S., Ju J., Meng L., Yang R., Lai S., Guo Z., Xie Y., and Chen W. T-cell epitopes in severe acute respiratory syndrome (SARS) coronavirus spike protein elicit a specific T-cell immune response in patients who recover from SARS. J. Virol. 78 (2004) 5612-5618
15. Kim T.W., Lee J.H., Hung C.F., Peng S., Roden R., Wang M.C., Viscidi R., Tsai Y.C., He L., Chen P.J., Boyd D.A., and Wu T.C. Generation and characterization of DNA vaccines targeting the nucleocapsid protein of severe acute respiratory syndrome coronavirus. J. Virol. 78 (2004) 4638-4645
16. Panesar N.S. Lymphopenia in SARS. Lancet 361 (2003) 1985
17. Gao W., Tamin A., Soloff A., Aiuto L.D., Nwanegbo E., Robbins P.D., Bellini W.J., Barratt-Boyes S., and Gambotto A. Effects of a SARS-associated coronavirus vaccine in monkeys. Lancet 362 (2003) 1895-1896
18. Yang Z.Y., Kong W.P., Huang Y., Roberts A., Murphy B.R., Subbarao K., and Nabel G.J. A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice. Nature 428 (2004) 561-564
19. He Y., Zhou Y., Wu H., Kou Z., Liu S., and Jiang S. Mapping of antigenic sites on the nucleocapsid protein of the severe acute respiratory syndrome coronavirus. J. Clin. Microbiol. 42 (2004) 5309-5314
20. Jin K., Chong X., Chen Z., Chen Z., Kang Y., Ma Y., Zhu K., Xie Q., Tu Y., Yua Y., and Wang B. Induction of Th1 type response by DNA vaccinations with N, M, and E genes against SARS-CoV in mice. Biochem. Biophys. Res. Commun. 328 (2005) 979-986
21. Wilson L., Mckinlay C., Gage P., and Ewart G. SARS coronavirus E protein forms cation-selective ion channels. Virology 330 (2004) 322-331
22. Ho Y., Lin P.H., Liu C.Y., Lee S.P., and Chao Y.C. Assembly of human severe acute respiratory syndrome coronavirus-like particles. Biochem. Biophys. Res. Commun. 318 (2004) 833-838
23. Liao Y., Lescar J., Tam J.P., and Liu D.X. Expression of SARS-coronavirus envelope protein in Escherichia coli cells alters membrane permeability. Biochem. Biophys. Res. Commun. 325 (2004) 374-380
24. Yang Y., Xiong Z., Zhang S., Yan Y., Nguyen J., Ng B., Lu H., Brendese J., Yang F., Wang H., and Yang X. Bcl-xL inhibits T-cell apoptosis induced by expression of SARS coronavirus E protein in the absence of growth factors. Biochem. J. 392 Pt 1 (2005) 135-143
25. Hoey J. Updated SARS case definition using laboratory criteria. C.M.A.J. 168 (2003) 1566-1567
26. + memory T cell depletion in patients with severe acute respiratory syndrome. Microbes Infect. 7 (2005) 427-436
27. + memory T cells. J. Exp. Med. 186 (1997) 859-865
28. Hoffmeister B., Kiecker F., Tesfa L., Volk H.D., Picker L.J., and Kern F. Mapping T cell epitopes by flow cytometry. Methods 292 (2003) 270-281
29. Buchholz U.J., Bukreyev A., Yang L., Lamirande E.W., Murphy B.R., Subbarao K., and Collins P.L. Contributions of the structural proteins of severe acute respiratory syndrome coronavirus to protective immunity. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 9804-9809
30. Sallusto F., Lenig D., Forster R., Lipp M., and Anzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401 (1999) 708-712
31. + effector and memory T cell generation. Nat. Rev. Immunol. 9 (2003) 835-842
32. Harari A., Vallelian F., Meylan P.R., and Pantaleo G. Functional heterogeneity of memory CD4 T cell responses in different conditions of antigen exposure and persistence. J. Immunol. 174 (2005) 1037-1045
33. +T-cell differentiation in response to viruses. Nat. Rev. Immunol. 3 (2003) 1-8
34. +T cell response. J. Immunol. 168 (2002) 5455-5464
35. Liu H., Ding Y.L., Han W., Liu M.Y., Tian R.Y., Yang S.L., and Gong Y. Recombinant scFv antibodies against E protein and N protein of severe acute respiratory syndrome virus. Acta Biochimica et Biophysica Sinica 36 (2004) 541-547