A traditional Japanese medicine mitigates TNBS-induced colitis in rats

Scandinavian Journal of Gastroenterology

Volumn 41, Issue 10, 2006, Pages 1183-1189

  Fukuda, Yoshihiro ^a   Tao, Yang ^b   Tomita, Toshihiko ^a   Hori, Kazutoshi ^a   Fukunaga, Ken ^a   Noguchi, Takayasu ^b   Hayashi, Tomoko ^c   Shimoyama, Tadashi ^d   Tahahashi, Ryoki ^b  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

^b Wakamoto Pharmaceutical Co Ltd   (Japan)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d HIROSAKI UNIVERSITY   (Japan)

Author keywords

Anti superoxide activity; Aspergillus oryzae koji; Experimental colitis; Inflammatory bowel disease; Microflora

Indexed keywords

ALCOHOL; AMYLASE; ASPERGILLUS ORYZAE KOJI EXTRACT; ENEMA; FUNGAL ENZYME; FUNGAL PROTEIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; STRONG WAKAMTO; SUPEROXIDE DISMUTASE; TRINITROBENZENESULFONIC ACID; UNCLASSIFIED DRUG; ZINC;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPERGILLUS ORYZAE; COLITIS; COLON MUCOSA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIETARY INTAKE; ENZYME ACTIVITY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LACTOBACILLUS; MACROPHAGE; MALE; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; RAT; SCORING SYSTEM; TRADITIONAL MEDICINE; WEIGHT REDUCTION;

ANIMALS; ASPERGILLUS ORYZAE; BODY WEIGHT; COLITIS; COLON; ENEMA; FECES; INTERLEUKIN-1BETA; INTESTINAL MUCOSA; JAPAN; MACROPHAGES; MALE; MEDICINE, EAST ASIAN TRADITIONAL; MEDICINE, ORIENTAL TRADITIONAL; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR-ALPHA; ZINC;

EID: 33749037986     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.1080/00365520600575704     Document Type: Article

References (40)

1. Sartor RB. Pathogenesis and immune mechanisms of chronic inflammatory bowel diseases. Am J Gastroenterol 1997;92:5-11.
2. Matsumoto T, Fujishima M. Epidemiologic aspects of ulcerative colitis in Japan: comparison with other countries. Nippon Rinsho 1999;57:2443-8.
3. Hugot JP, Chamaillard M, Zouali H, Lesage S, Cezard JP, Belaiche J, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001;411:599-603.
4. Hampe J, Cuthbert A, Croucher PJ, Mirza MM, Mascheretti S, Fisher S, et al. Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. Lancet 2001;357:1925-8.
5. Yamazaki K, Takazoe M, Tanaka T, Kazumon T, Nakamura Y. Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease. J Hum Genet 2002;47:469-72.
6. Inoue N, Tamura K, Kinouchi Y, Fukuda Y, Takahashi S, Ogura Y, et al. Lack of common NOD2 variants in Japanese patients with Crohn's disease. Gastroenterology 2002;123:86-91.
7. Yao T, Matsui T, Hiwatashi N. Crohn's disease in Japan: diagnostic criteria and epidemiology. Dis Colon Rectum 2000;43:S85-93.
8. Sartor RB. Role of the enteric microflora in the pathogenesis of intestinal inflammation and arthritis. Aliment Pharmacol Ther 1997;11:17-22.
9. Harper PH, Truelove SC, Lee EC, Kettlewell MG, Jewell DP. Split ileostomy and ileocolostomy for Crohn's disease of the colon and ulcerative colitis: a 20-year survey. Gut 1983;24:106-13.
10. D'Haens GR, Geboes K, Peeters M, Baert F, Penninckx F, Rutgeerts P, et al. Early lesions of recurrent Crohn's disease caused by infusion of intestinal contents in excluded ileum. Gastroenterology 1998;114:262-7.
11. Taurog JD, Richardson JA, Croft JT, Simmons WA, Zhou M, Fermandez-Sueiro JL, et al. The germ-free state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats. J Exp Med 1994;180:2359-64.
12. Contractor NV, Bassiri H, Reya T, Park AY, Baumgart DC, Wasik MA, et al. Lymphoid hyperplasia, autoimmunity, and compromised intestinal intraepithelial lymphocyte development in colitis-free gnotobiotic IL-2-deficient mice. J Immunol 1998;160:385-94.
13. Sellon RK, Tonkonogy S, Schultz M, Dieleman LA, Grenther W, Balish E, et al. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun 1998;66:5224-31.
14. Dianda L, Hanby AM, Wright NA, Sebesteny A, Hayday AC, Qwen MJ. T-cell receptor-alpha beta-deficient mice fail to develop colitis in the absence of a microbial environment. Am J Pathol 1997;15:91-7.
15. Lilly DM, Stilwell RH. Probiotics: growth promoting factors produced by microorganisms. Science 1965;47:747-8.
16. Fuller R. Probiotics in man and animals. J Appl Bacteriol 1989;66:365-78.
17. Fabia R, Ar'Rajab A, Johansson ML, Willen R, Andersson R, Molin G, et al. The effect of exogenous administration of Lactobacillus reuteri R2LC and oat fiber on acetic acid-induced colitis in the rat. Scand J Gastroenterol 1993;28:155-62.
18. Madsen KL, Doyle JS, Jewell LD, Tavernini MM, Fedorak RN. Lactobacillus species prevents colitis in interleukin 10 gene-deficient mice. Gastroenterology 1999;116:1107-14.
19. Shibolet O, Karmeli F, Eliakim R, Swennen E, Brigidi P, Gionchetti P, et al. Variable response to probiotics in two models of experimental colitis in rats. Inflamm Bowel Dis 2002;8:399-406.
20. Gionchetti P, Rizzello F, Venturi A, Brigidi P, Matteuzzi D, Bazzocchi G, et al. Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial. Gastroenterology 2000;119:305-9.
21. Guslandi M, Mezzi G, Sorghi M, Testoni PA. Saccharomyces boulardii in maintenance treatment of Crohn's disease. Dig Dis Sci 2000;45:1462-4.
22. Venturi A, Gionchetti P, Rizzello F, Johansson R, Zucconi E, Brigidi P, et al. Impact on the composition of the faecal flora by a new probiotic preparation: preliminary data on maintenance treatment of patients with ulcerative colitis. Aliment Pharmacol Ther 1999;13:1103-8.
23. Morris GP, Beck PL, Herridge MS, Depew WT, Szewczuk MR, Wallace JL. Hapten-induced model of chronic inflammation and ulceration in the rat colon. Gastroenterology 1989;96:795-803.
24. Wallace JL, Keenan CM. An orally active inhibitor of leukotriene synthesis accelerates healing in a rat model of colitis. Am J Physiol 1990;258:G527-34.
25. Krawisz JE, Sharon P, Stenson WF. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. Gastroenterology 1984;87:1344-50.
26. Benno Y, Mitsuoka T. Impact of Bifidobacterium longum on human fecal microflora. Microbiol Immunol 1992;36:683-94.
27. Sun FF, Lai PS, Yue G, Yin K, Nagele RG, Tong DM, et al. Pattern of cytokine and adhesion molecule mRNA in hapten-induced relapsing colon inflammation in the rat. Inflammation 2001;25:33-45.
28. Arias-Negrete S, Keller K, Chadee K. Proinflammatory cytokines regulate cyclooxygenase-2 mRNA expression in human macrophages. Biochem Biophys Res Commun 1995;208:582-9.
29. Mahida YR. The key role of macrophages in the immunopathogenesis of inflammatory bowel disease. Inflamm Bowel Dis 2000;6:21-33.
30. Wallace JL, MacNaughton WK, Morris GP, Beck PL. Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease. Gastroenterology 1989;96:29-36.
31. Dinarello CA. The interleukin-1 family: 10 years of discovery. FASEB J 1994;8:1314-25.
32. Mahida YR, Wu K, Jewell DP. Enhanced production of interleukin 1-beta by mononuclear cells isolated from mucosa with active ulcerative colitis of Crohn's disease. Gut 1989;30:835-8.
33. Casini-Raggi V, Kam L, Chong YJ, Fiocchi C, Pizarro TT, Cominelli F. Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease. A novel mechanism of chronic intestinal inflammation. J Immunol 1995;154:2434-40.
34. Kawasumi T, Sato M, Tsuriya Y, Ueno S. Antioxidant activity of a medicine based on Aspergillus oryzae NK koji measured by a modified t-butyl peroxyl radical scavenging assay. Biosci Biotechnol Biochem 1999;63:581-4.
35. Grisham MB, Volkmer C, Tso P, Yamada T. Metabolism of trinitrobenzene sulfonic acid by the rat colon produces reactive oxygen species. Gastroenterology 1991;101:540-7.
36. Simmonds NJ, Rampton DS. Inflammatory bowel disease: a radical view. Gut 1993;34:865-8.
37. Seo HG, Takata I, Nakamura M, Tatsumi H, Suzuki K, Fujii J, et al. Induction of nitric oxide synthase and concomitant suppression of superoxide dismutases in experimental colitis in rats. Arch Biochem Biophys 1995;324:41-7.
38. Sturniolo GC, Mestriner C, Lecis PE, D'Odorico A, Venturi C, Irato P, et al. Altered plasma and mucosal concentrations of trace elements and antioxidants in active ulcerative colitis. Scand J Gastroenterol 1998;33:644-9.
39. Kruse-Jarres JD. The significance of zinc for humoral and cellular immunity. J Trace Elem Electrolytes Health Dis 1989;3:1-8.
40. Sands BE. Therapy of inflammatory bowel disease. Gastroenterology 2000;118:S68-82.