Improved detectability in pharmacokinetic study of tibolone by gas chromatography-high resolution mass spectrometry with selected ion monitoring

Talanta

Volumn 70, Issue 1 SPEC. ISS., 2006, Pages 37-42

  Son, Junghyun ^a   Moon, Ju Yeon ^a   Kim, Seol A ^a,b   Cho, Young Dae ^a,b   Kim, Jong Dae ^a,b   Kim, Dong Hyun ^a   Choi, Man Ho ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Kyung Hee University   (South Korea)

Author keywords

GC HRMS; Pharmacokinetic; Tibolone; Trimethylsilylation

Indexed keywords

DERIVATIVES; DRUG PRODUCTS; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; SAMPLING;

HIGH RESOLUTION MASS SPECTROMETRY (HRMS); SELECTED ION MONITORING; TIBOLONE; TRIMETHYLSILYLATION;

PHARMACOKINETICS;

EID: 33749028593     PISSN: 00399140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.talanta.2006.02.003     Document Type: Article

References (16)

1. Vogelvang T.E., van der Mooren M.J., and Mijatovic V. Treat. Endocrinol. 3 (2004) 105
2. Sadarangani A., Salgado A.M., Kato S., Pinto M., Carvajal A., Monso C., Owen G.I., and Vigil P. Biol. Res. 38 (2005) 245
3. Vos R.M.E., Krebbers S.F.M., Verhoeven C.H.J., and Delbressine L.P.C. Drug Metabol. Dispos. 30 (2002) 106
4. Timmer C.J., Verheul H.A.M., and Doorstam D.P. Br. J. Clin. Pharmacol. 54 (2002) 101
5. Verhoeven C.H.J., Vos R.M.E., and Delbressine L.P.C. Eur. J. Drug Metabol. Pharmacokinet. 27 (2002) 1
6. Timmers C.J., and Huisman J.A.M. Pharmacotherapy 22 (2002) 310
7. Dueker S.R., Lin Y., Buchholz B.A., Schneider P.D., Lamé M.W., Segall H.J., Vogel J.S., and Clifford A.J. J. Lipid Res. 41 (2000) 1790
8. Lappin G., and Garner R.C. Nat. Rev. Drug Discov. 2 (2003) 233
9. Choi M.H., Skipper P.L., Wishnok J.S., and Tannenbaum S.R. Drug Metabol. Dispos. 33 (2005) 714
10. Choi M.H., Chung B.C., Lee W., Lee U.C., and Kim Y. Rapid Commun. Mass Spectrom. 13 (1999) 376
11. Choi M.H., Kim K.R., and Chung B.C. Analyst 125 (2000) 711
12. Choi M.H., and Chung B.C. Analyst 126 (2001) 306
13. Choi M.H., Yoo Y.S., and Chung B.C. J. Invest. Dermatol. 116 (2001) 57
14. Gross C.M., Davis I.M., Arrendale R.F., Jersey J., and Amin J. J. Pharm. Biomed. Anal. 12 (1994) 195
15. Machnik M., Geyer H., Horning S., Breidach A., Delahaut P., and Schänzer W. J. Chromatogr. B 723 (1999) 147
16. Ham A.L., Ranasinghe A., Morinello E.J., Makamura J., Upton P.B., Johnson F., and Swenberg J.A. Chem. Res. Toxicol. 12 (1999) 1240