메뉴 건너뛰기




Volumn 38, Issue 2-3, 2005, Pages 245-258

In vivo and in vitro estrogenic and progestagenic actions of Tibolone

Author keywords

Breast endometrium cancer; Estrogenic; HRT; Progestagenic and tibolone

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; ESTROGEN; ESTROGEN RECEPTOR; GESTAGEN; PROGESTERONE; PROTEIN BCL XL; SELECTIVE ESTROGEN RECEPTOR MODULATOR; STAT5 PROTEIN; THROMBOPLASTIN; TIBOLONE;

EID: 27544502469     PISSN: 07169760     EISSN: None     Source Type: Journal    
DOI: 10.4067/S0716-97602005000200014     Document Type: Article
Times cited : (12)

References (37)
  • 1
    • 0020074149 scopus 로고
    • The menopause: Benefits and risks of estrogen-progestogen replacement therapy
    • GAMBRELL RD (1982) The menopause: benefits and risks of estrogen-progestogen replacement therapy. Fertil Steril 37(4): 457-74
    • (1982) Fertil. Steril. , vol.37 , Issue.4 , pp. 457-474
    • Gambrell, R.D.1
  • 2
    • 0038116381 scopus 로고    scopus 로고
    • Bone loss and bone size after menopause
    • AHLBORG HG, JOHNELL O, TURNER CH (2003) Bone loss and bone size after menopause. Engl J Med 349(4): 327-34
    • (2003) Engl. J. Med. , vol.349 , Issue.4 , pp. 327-334
    • Ahlborg, H.G.1    Johnell, O.2    Turner, C.H.3
  • 3
    • 18144421167 scopus 로고    scopus 로고
    • Endometrial cancer and hormone-replacement therapy in the Million Women Study
    • Million Women Study Collaborators
    • BERAL V, BULL D, REEVES G; Million Women Study Collaborators. (2005) Endometrial cancer and hormone-replacement therapy in the Million Women Study. Lancet. 365(9470): 1543-51
    • (2005) Lancet , vol.365 , Issue.9470 , pp. 1543-1551
    • Beral, V.1    Bull, D.2    Reeves, G.3
  • 4
    • 0036328330 scopus 로고    scopus 로고
    • In vitro studies of tibolone in breast cells
    • GOMPEL A, CHAOUAT M, Jacob D (2002) In vitro studies of tibolone in breast cells. Fertil Steril 78(2): 351-359
    • (2002) Fertil. Steril. , vol.78 , Issue.2 , pp. 351-359
    • Gompel, A.1    Chaouat, M.2    Jacob, D.3
  • 5
    • 0032737196 scopus 로고    scopus 로고
    • Tibolone, a steroid with a tissue-specific hormonal profile, completely prevents ovariectomy-induced bone loss in sexually mature rats
    • EDERVEEN AG, KLOOSTERBOER HJ (1999). Tibolone, a steroid with a tissue-specific hormonal profile, completely prevents ovariectomy-induced bone loss in sexually mature rats. J Bone Miner Res 14(11): 1963-1970
    • (1999) J. Bone Miner. Res. , vol.14 , Issue.11 , pp. 1963-1970
    • Ederveen, A.G.1    Kloosterboer, H.J.2
  • 7
    • 3342906787 scopus 로고    scopus 로고
    • Comparison of the effects of tibolone and estrogen replacement therapy on echocardiographic basic cardiac functions in post-menopausal women: A randomized placebo controlled study
    • TASKIN O, MUDERRISOGLU H, AKAR M, SIMSEK M, MENDILCIOGLU I, KURSUN S (2004) Comparison of the effects of tibolone and estrogen replacement therapy on echocardiographic basic cardiac functions in post-menopausal women: a randomized placebo controlled study. Maturitas 48(4): 354-9
    • (2004) Maturitas , vol.48 , Issue.4 , pp. 354-359
    • Taskin, O.1    Muderrisoglu, H.2    Akar, M.3    Simsek, M.4    Mendilcioglu, I.5    Kursun, S.6
  • 8
    • 0036348830 scopus 로고    scopus 로고
    • Effect of tibolone (Org OD14) and its metabolites on aromatase and estrone sulfatase activity in human breast adipose stromal cells and in MCF-7 and T47D breast cancer cells
    • VAN DE VEN J, DONKER GH, SPRONG M (2002) Effect of tibolone (Org OD14) and its metabolites on aromatase and estrone sulfatase activity in human breast adipose stromal cells and in MCF-7 and T47D breast cancer cells. J Steroid Biochem Mol Biol 81(3): 237-47
    • (2002) J. Steroid. Biochem. Mol. Biol. , vol.81 , Issue.3 , pp. 237-247
    • Van De Ven, J.1    Donker, G.H.2    Sprong, M.3
  • 9
    • 0034086140 scopus 로고    scopus 로고
    • Origins and evolutionary diversification of the nuclear receptor superfamily
    • OWEN GI, ZELENT A (2000) Origins and evolutionary diversification of the nuclear receptor superfamily. Cell Mol Life Sci 57(5): 809-27
    • (2000) Cell. Mol. Life Sci. , vol.57 , Issue.5 , pp. 809-827
    • Owen, G.I.1    Zelent, A.2
  • 10
    • 0042388370 scopus 로고    scopus 로고
    • Estrogen receptor (ER) betal and ERbetacx/beta2 inhibit ERalpha function differently in breast cancer cell line MCF7
    • OMOTO Y, EGUCHI H, YAMAMOTO-YAMAGUCHI Y (2003) Estrogen receptor (ER) betal and ERbetacx/beta2 inhibit ERalpha function differently in breast cancer cell line MCF7. Oncogene 22(32): 5011-20
    • (2003) Oncogene , vol.22 , Issue.32 , pp. 5011-5020
    • Omoto, Y.1    Eguchi, H.2    Yamamoto-Yamaguchi, Y.3
  • 11
    • 0037457078 scopus 로고    scopus 로고
    • Naturally occurring dominant-negative Stat5 suppresses transcriptional activity of estrogen receptors and induces apoptosis in T47D breast cancer cells
    • 22
    • YAMASHITA H, IWASE H, TOMOYAMA T (2003) Naturally occurring dominant-negative Stat5 suppresses transcriptional activity of estrogen receptors and induces apoptosis in T47D breast cancer cells. Oncogene 20; 22(11): 1638-52
    • (2003) Oncogene , vol.20 , Issue.11 , pp. 1638-1652
    • Yamashita, H.1    Iwase, H.2    Tomoyama, T.3
  • 12
    • 0036783353 scopus 로고    scopus 로고
    • Anti-epidermal growth factor receptor-antibody therapy for treatment of breast cancer
    • A.H.R. A 101
    • SOLBACH C, ROLLER M, AHR A (2002) Anti-epidermal growth factor receptor-antibody therapy for treatment of breast cancer. Int J Cancer 1;101(4): 390-4
    • (2002) Int. J. Cancer. , vol.1 , Issue.4 , pp. 390-394
    • Solbach, C.1    Roller, M.2
  • 13
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • HANANHAN D, WEINBERG RA (2000) The hallmarks of cancer. Cell. 100(1): 57-70
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hananhan, D.1    Weinberg, R.A.2
  • 14
    • 0034851253 scopus 로고    scopus 로고
    • The tissue factor: VIIa: Clinical significance, structure function, relationships and its role in signaling and metastasis
    • KONINGSBERG W, KIRCHHOFER D. RIEDERER M (2001) The tissue factor: VIIa: clinical significance, structure function, relationships and its role in signaling and metastasis. Tromb and Haemost 86(5): 757-71
    • (2001) Tromb. and Haemost. , vol.86 , Issue.5 , pp. 757-771
    • Koningsberg, W.1    Kirchhofer, D.2    Riederer, M.3
  • 15
    • 0034086722 scopus 로고    scopus 로고
    • Tissue factor expression in breast tissue: Its correlation with prognosis and plasma concentration
    • UENO T, TOI M, KOIKE M (2000) Tissue factor expression in breast tissue: its correlation with prognosis and plasma concentration. Br J. Cancer 83(2): 164-70
    • (2000) Br. J. Cancer. , vol.83 , Issue.2 , pp. 164-170
    • Ueno, T.1    Toi, M.2    Koike, M.3
  • 16
    • 0029854237 scopus 로고    scopus 로고
    • Expression of tissue factor in tumor stroma correlates with progression to invasive human breast cancer: Paracrine regulated by carcinoma cell-derived members of the transforming growth factor beta family
    • VRANA JA, STANG MT, Grande JP (1996) Expression of tissue factor in tumor stroma correlates with progression to invasive human breast cancer: paracrine regulated by carcinoma cell-derived members of the transforming growth factor beta family. Cancer Res 56(21): 5063-70
    • (1996) Cancer. Res. , vol.56 , Issue.21 , pp. 5063-5070
    • Vrana, J.A.1    Stang, M.T.2    Grande, J.P.3
  • 17
    • 0031882775 scopus 로고    scopus 로고
    • Activation of coagulation and angiogeneis in cancer: Inmunohistochemical localization in situ of clotting proteins and vascular endothelial growth factor in human cancer
    • SHOJI M, HANCOCK W, ABE M (1998) Activation of coagulation and angiogeneis in cancer: Inmunohistochemical localization in situ of clotting proteins and vascular endothelial growth factor in human cancer. Am J Pathol 52(2): 399-411
    • (1998) Am. J. Pathol. , vol.52 , Issue.2 , pp. 399-411
    • Shoji, M.1    Hancock, W.2    Abe, M.3
  • 18
    • 0041941282 scopus 로고    scopus 로고
    • Anti-apoptotic effect of coagulation factor VIIa
    • SORENSEN BB, RAO LV, TORNEHAVE D (2003) Anti-apoptotic effect of coagulation factor VIIa. Blood 102(5): 1708-15
    • (2003) Blood , vol.102 , Issue.5 , pp. 1708-1715
    • Sorensen, B.B.1    Rao, L.V.2    Tornehave, D.3
  • 19
    • 0041568662 scopus 로고    scopus 로고
    • Pro-apoptotic activity of transiently expressed BCL-2 occurs independent of BAX and BAK
    • 89
    • SUBRAMANIAN T, CHINNNADURAI G (2003) Pro-apoptotic activity of transiently expressed BCL-2 occurs independent of BAX and BAK. J Cell Biochem 15; 89(6): 1102-14
    • (2003) J. Cell. Biochem. , vol.15 , Issue.6 , pp. 1102-1114
    • Subramanian, T.1    Chinnnadurai, G.2
  • 20
    • 0018079661 scopus 로고
    • Establishment and characterization of three new continuous cell lines derived from human breast carcinomas
    • ENGEL LW, YOUNG NA, TRALKA TS (1978). Establishment and characterization of three new continuous cell lines derived from human breast carcinomas. Cancer Res 38(10): 3352-64
    • (1978) Cancer. Res. , vol.38 , Issue.10 , pp. 3352-3364
    • Engel, L.W.1    Young, N.A.2    Tralka, T.S.3
  • 21
    • 0016831054 scopus 로고
    • MCF-7; a human breast cancer cell line with estrogen, androgen, progesterone, and glucocorticoid receptors
    • HORWITZ KB, COSTLOW ME, McGUIRE WL (1975) MCF-7; a human breast cancer cell line with estrogen, androgen, progesterone, and glucocorticoid receptors. Steroids 26(6): 785-95.
    • (1975) Steroids , vol.26 , Issue.6 , pp. 785-795
    • Horwitz, K.B.1    Costlow, M.E.2    McGuire, W.L.3
  • 22
    • 0021865277 scopus 로고
    • Establishment of a new human endometrial adenocarcinoma cell line, Ishikawa cells, containing estrogen and progesterone receptors
    • NISHIDA M, KASAHARA K, KANEKO M (1985) Establishment of a new human endometrial adenocarcinoma cell line, Ishikawa cells, containing estrogen and progesterone receptors. Nippon Sanka Fujinka Gakkai Zasshi 37(7): 1103-1111
    • (1985) Nippon Sanka Fujinka Gakkai Zasshi , vol.37 , Issue.7 , pp. 1103-1111
    • Nishida, M.1    Kasahara, K.2    Kaneko, M.3
  • 23
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • CHOMCZYNSKI P, SACCHI N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162(1): 156-159
    • (1987) Anal. Biochem. , vol.162 , Issue.1 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 24
    • 0038583811 scopus 로고    scopus 로고
    • The effect of progesterone and synthetic progestins on serum - And estradiol-stimulated proliferation of human breast cancer cells
    • SEEGER H, WALLWIENER D, MUECK AO (2003) The effect of progesterone and synthetic progestins on serum - and estradiol-stimulated proliferation of human breast cancer cells Horm Metab Res 35(2): 76-80
    • (2003) Horm. Metab. Res. , vol.35 , Issue.2 , pp. 76-80
    • Seeger, H.1    Wallwiener, D.2    Mueck, A.O.3
  • 25
    • 0026537964 scopus 로고
    • Immunocytochemical determination of estrogen and progesterone receptors in human endometrial adenocarcinoma cells (Ishikawa cells)
    • HATA H, KURAMOTO H (1992) Immunocytochemical determination of estrogen and progesterone receptors in human endometrial adenocarcinoma cells (Ishikawa cells). J Steroid Biochem Mol Biol 42(2): 201-210
    • (1992) J. Steroid. Biochem. Mol. Biol. , vol.42 , Issue.2 , pp. 201-210
    • Hata, H.1    Kuramoto, H.2
  • 27
    • 0036674264 scopus 로고    scopus 로고
    • Effects of tibolone and continuous combined hormone replacement therapy on bleeding rates, quality of life and tolerability in postmenopausal women
    • HUBER J, PALACIOS S, BERGLUND L (2002) Effects of tibolone and continuous combined hormone replacement therapy on bleeding rates, quality of life and tolerability in postmenopausal women. BJOG 109(8): 886-93
    • (2002) BJOG , vol.109 , Issue.8 , pp. 886-893
    • Huber, J.1    Palacios, S.2    Berglund, L.3
  • 29
    • 0034724882 scopus 로고    scopus 로고
    • Absent correlation between vaginal bleeding and estradiol levels or endometrial morphology during tibolone use in early postmenopausal women
    • BERNING B, van KUIJK C, BENNINK HJ (2000) Absent correlation between vaginal bleeding and estradiol levels or endometrial morphology during tibolone use in early postmenopausal women. Maturitas 35(1): 81-8
    • (2000) Maturitas , vol.35 , Issue.1 , pp. 81-88
    • Berning, B.1    van Kuijk, C.2    Bennink, H.J.3
  • 30
    • 0042766377 scopus 로고    scopus 로고
    • Anti-estrogens in the treatment of breast cancer: Current status and future directions
    • BARKER S (2003) Anti-estrogens in the treatment of breast cancer: current status and future directions. Curr Opin Investig Drugs 4(6): 652-657
    • (2003) Curr. Opin. Investig. Drugs , vol.4 , Issue.6 , pp. 652-657
    • Barker, S.1
  • 31
    • 0036357646 scopus 로고    scopus 로고
    • The role of Stat5 in estrogen receptor-positive breast cancer
    • YAMASHITA H, IWASE H (2002). The role of Stat5 in estrogen receptor-positive breast cancer. Breast Cancer 9(4): 312-8
    • (2002) Breast Cancer , vol.9 , Issue.4 , pp. 312-318
    • Yamashita, H.1    Iwase, H.2
  • 32
    • 7944233465 scopus 로고    scopus 로고
    • Role of STATs as downstream signal transducers in Src family kinase-mediated tumorigenesis
    • SILVA CM (2004) Role of STATs as downstream signal transducers in Src family kinase-mediated tumorigenesis. Oncogene 3(48): 8017-8023
    • (2004) Oncogene , vol.3 , Issue.48 , pp. 8017-8023
    • Silva, C.M.1
  • 33
    • 0038481254 scopus 로고    scopus 로고
    • Low levels of tissue factor pathway inhibitor (TFPI) increase the risk of venous thrombosis
    • DAHM A, Van HYLCKAMA VLIEG A, BENDZ B (2003) Low levels of tissue factor pathway inhibitor (TFPI) increase the risk of venous thrombosis. Blood 101(11): 4387-92
    • (2003) Blood , vol.101 , Issue.11 , pp. 4387-4392
    • Dahm, A.1    Van Hylckama Vlieg, A.2    Bendz, B.3
  • 36
    • 0034987346 scopus 로고    scopus 로고
    • Tibolone: A steroid with a tissue-specific mode of action
    • KLOOSTERBOER HJ (2001). Tibolone: a steroid with a tissue-specific mode of action. J Steroid Biochem Mol Biol 76(1-5): 231-238
    • (2001) J. Steroid. Biochem. Mol. Biol. , vol.76 , Issue.1-5 , pp. 231-238
    • Kloosterboer, H.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.