Determination of dissociation constants of folic acid, methotrexate, and other photolabile pteridines by pressure-assisted capillary electrophoresis

Electrophoresis

Volumn 27, Issue 17, 2006, Pages 3399-3409

  Szakács, Zoltán ^a   Noszál, Béla ^b,c  

^a EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

Acid dissociation constant; Folate; Methotrexate; Photodegradation; Pressure assisted capillary electrophoresis

Indexed keywords

ALKALINITY; DISSOCIATION; IONIC STRENGTH; ORGANIC ACIDS; TITRATION; VOLTAMMETRY;

ACID DISSOCIATION CONSTANTS; COMPLETE SETS; DISSOCIATION CONSTANT; FOLATES; FOLIC ACIDS; METHOTREXATE; PHOTO DEGRADATION; PRESSURE-ASSISTED CAPILLARY ELECTROPHORESIS; PTERIDINES; SELF-ASSOCIATIONS;

CAPILLARY ELECTROPHORESIS;

ACID; AMINOPTERIN; BASE; BENZOIC ACID; DIHYDROFOLATE REDUCTASE; FOLIC ACID; METHOTREXATE; PROTON; PTERIDINE DERIVATIVE; PTERIN DERIVATIVE;

ACCURACY; ACIDITY; ARTICLE; BINDING KINETICS; CAPILLARY ELECTROPHORESIS; CONCENTRATION RESPONSE; DISSOCIATION CONSTANT; DRUG DETERMINATION; DRUG STRUCTURE; IONIC STRENGTH; NUCLEAR MAGNETIC RESONANCE; PH; PHOTODEGRADATION; POTENTIOMETRIC TITRATION; PRESSURE; QUANTITATIVE ANALYSIS; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 33748943839     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.200600128     Document Type: Article

References (52)

1. Blakley, R. L., Benkovic, S. J. (Eds.), Folates and Pterins. Chemisty and Biochemistry of Folates, Wiley, New York 1984, Vol. 1, pp. 191-253.
2. Cheung, H. T A., Birdsall, B., Frenkiel, T A., Chau, D. D., Feeney, J., Biochemistry 1993,32,6846-6854.
3. Náy-Szabó, G., Nagy, P., Can. J. Chem, 1985, 63,1694-1698.
4. Cheung, H. T A., Birdsall, B., Feeney, J., FEBS Lett. 1992, 312,147-151.
5. Albert, A., Biochem. J. 1953,54, 646-654.
6. Poe, M., J. Biol. Chem. 1973,248, 7025-7032.
7. Poe, M., J. Biol. Chem. 1977,252,3724-3728.
8. Monópoli, V. D., Thomas, A. H., Capparelli, A. L., Int J. Chem. Kinet 2000,32,231-237.
9. Thomas, A. H., Suárez, G., Cabrerizo, F M., Martino, R., Capparelli, A. L., J. Photochem, Photobiol. A- Chem. 2000, 135,147-154.
10. Avdeef, A., Curr Topics Med. Chem. 2001, 1, 277-351.
11. Thomas, A. H., Suárez, G., Cabrerizo, F. M., Einschlag, F. S. G. et al., Helv. Chim. Acta 2002, 85, 2300-2315.
12. Akhtar, M. J., Khan, M. A., Ahmad, I., J. Pharm. Biomed. Anal. 1999,25,269-275.
13. Akhtar, M. J., Khan, M. A., Ahmad, I., J. Pharm. Biomed. Anal. 2003,31, 579-588.
14. Chatterji, D. C., Gallelli, J. F., J. Pharm. Sci. 1978, 67, 526-531.
15. Sabry, S. M., Abdel-Hady, M., Elsayed, M., Fahmy, O. T, Maher, H. M., J. Pharm. Biomed. Anal. 2003,32,409-423.
16. Gottarelli, G., Mezzina, E., Spada, G. R, Carsughi, F. et al., Helv. Chim. Acta 1996, 79, 220-234.
17. Sczensny, F., Hempel, G., Boos, H., Blaschke, G., J. Chromatogr B 1998, 718,177-185.
18. Han, F., Huynh, B. H., Shi, H., Lin, B., Ma, Y., Anal. Chem. 1999, 71,1265-1269.
19. Beckers, J. L., Everaerts, F M., Ackermans, M. T., J. Chromatogr. A 1991, 537, 407-428.
20. Cleveland, J. A. Jr., Benkö, M. H., Gluck, S. J., Walbroehi, Y. M., J. Chromatogr 1993, 652, 301-308.
21. Gluck, S. J., Cleveland J. A. Jr., J. Chromatogr A 1994,680, 49-56.
22. Gluck, S. J., Steele, K. P., Benkö, M. H., J. Chromatogr. A 1996,745,117-125.
23. Koval, D., Kašička, V, Jirácek, J., Collinsová, M., Electrophoresis 2003,24, 774-781.
24. Vceláková, K., Zusková, I, Kenndler, E., Gaš, B., Electrophoresis 2004,25, 309-317.
25. Poole, S. K., Patel, S., Dehring, K., Workman, H., Poole, C. F., J. Chromatogr A 2004,1037, 445-454.
26. Jankowsky, R., Friebe, M., Noll, B., Johannsen, B., J. Chromatogr A 1999,833,83-96.
27. Jia, Z., Ramstad, T., Zhong, M., Electrophoresis 2001, 22, 1112-1118,
28. Kibbey, C. E., Poole, S. K., Robinson, B., Jackson, J. D., Durham, D., J. Pharm. Sci. 2001, 90,1164-1175.
29. Wan, H., Holmén, A., Nagard, M., Lindberg, W., J. Chromatogr A 2002,979,369-377.
30. Ishihama, Y, Nakamura, M., Miwa, T., Kajima, T, Asakawa, N., J. Pharm. Sci. 2002, 91, 933-942.
31. Wan, H., Holmén, A. G., Wang, Y., Lindberg, W. et al., Rapid Commun. Mass Spectrom. 2003,17,2639-2648.
32. Kenseth, J., Bastin, A., Franck, E., Strasburg, R., In: Proceedings of the Presentation at the 2002 American Association of Pharmaceutical Scientists Annual Meeting and Exposition, November 10th-14th, 2002, Toronto, http://www.combisep.com.
33. Miller, J. M., Blackburn, A. C., Shi, Y., Melzak, A. J., Ando, H. Y, Electrophoresis 2002, 23, 2833-2841.
34. Örnskov, E., Linusson, A., Folestad, S., J. Pharm. Biomed. Anal. 2003, 33, 379-391.
35. Sastre de Vicente, M. E., Curr. Top. Solut, Chem. 1997, 2, 157-181.
36. Davies, C. W., Ion Association, Butterworths, London 1962, p. 41.
37. Nancollas, G. H., Tomson, M. B., Pure Appl. Chem. 1982, 54,2675-2692.
38. Braibanti, A., Ostacoli, G., Paoletti, R, Pettit, L. D., Sammartano, S., Pure Appl. Chem. 1987,59,1721-1728.
39. Sigel, H., Zuberbühler, A. D., Yamauchi, O., Anal. Chim. Acta 1991,255,63-72.
40. Barriada, J. L., Brandariz, I., Armesto, X. L., Herrero, R., Sastre de Vicente, M. E., J. Chem. Soc. Faraday Trans. 1994, 94,3093-3096.
41. Martell, A. E., Smith, R. M. (Eds.), Critical Stability Constants, Plenum Press, New York 1974-1989.
42. Szakács, Z., Béni, Sz., Varga, Z., Orfi, L. et al., J. Med. Chem. 2005,48,249-255.
43. Avdeef, A., Box, K. J., Comer, J. E. A., Gilges, M. et al., J. Pharm. Biomed. Anal. 1999,20,631-641.
44. Wooley, E. M., Hepler, L. G., Anal. Chem. 1972, 44, 1520-1523.
45. Szakács, Z., Hägele, G., Tyka, R., Anal. Chim. Acta 2004, 522,247-258.
46. Hoult, D. I., J. Magn. Reson. 1976,21, 337-347.
47. Sjöberg, S., Pure Appl. Chem. 1997, 69,1549-1570.
48. Perrin, C. L., Fabian, M. A., Anal. Chem. 1996, 68, 2127-2134.
49. Friedl, W., Reijenga, J. C., Kenndler, E., J. Chromatogr A 1995, 709,163-170.
50. Castagnola, M., Rossetti, D. V., Inzitari, R., Vitali, A. et al., Electrophoresis 2003,24, 801-807.
51. Mazák, K., Szakács, Z., Nemes, A., Noszál, B., Electrophoresis 2000, 21, 2417-2423.
52. Rosés, M., Bosch, E., J. Chromatogr A 2002,942,145-156.