Study of stability of methotrexate in acidic solution Spectrofluorimetric determination of methotrexate in pharmaceutical preparations through acid-catalyzed degradation reaction

Journal of Pharmaceutical and Biomedical Analysis

Volumn 32, Issue 3, 2003, Pages 409-423

  Sabry, Suzy M ^a   Abdel Hady, M ^a   Elsayed, M ^a   Fahmy, Osama T ^a   Maher, Hadir M ^a  

^a Alexandria University Faculty of Pharmacy   (Egypt)

Author keywords

Acidic solution; Methotrexate; Spectrofluorimetric determination

Indexed keywords

4 AMINO 10 METHYLPTEROIC ACID; ACETYLACETONE; ACID; FLUORESCAMINE; FORMALDEHYDE; METHOTREXATE; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIMETABOLITE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS;

ACCURACY; ARTICLE; BLOOD SAMPLING; CATALYSIS; DRUG BLOOD LEVEL; DRUG DEGRADATION; DRUG DETERMINATION; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG HYDROLYSIS; DRUG STABILITY; FLUORESCENCE; HUMAN; INTERMETHOD COMPARISON; POLYMERIZATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SPECTROFLUOROMETRY; VALIDATION PROCESS; CALIBRATION; CHEMISTRY; HYDROLYSIS; KINETICS; PH; SOLUTION AND SOLUBILITY; STANDARD; TABLET;

ACIDS; ANTIMETABOLITES, ANTINEOPLASTIC; CALIBRATION; CATALYSIS; DRUG STABILITY; FLUORESCAMINE; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; INDICATORS AND REAGENTS; KINETICS; METHOTREXATE; REFERENCE STANDARDS; SOLUTIONS; SPECTROMETRY, FLUORESCENCE; TABLETS;

EID: 0142155216     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(03)00239-5     Document Type: Article

References (56)

1. Parfitt K., Sweetman S.C., Blake P.S., Parsons A.V. Martindale, the Extra Pharmacopoeia. 32th ed :1999;547-551 Pharmaceutical Press, London.
2. United States Pharmacopeia XXIV, The National Formulary 19, US Pharmacopeial convention, INC, 2000, pp. 984-985, 2151.
3. British Pharmacopoeia, Stationery Office, London, 1998, pp. 872, 1805.
4. McCrudden E.A., Tett S.E. J. Chromatogr. Biomed. Appl. 721:1999;87-92.
5. Emara S., Askal H., Masujima T. Biomed. Chromatogr. 12:1998;338-342.
6. Yu Z., Westerlund D., Boos K.S. J. Chromatogr. Biomed. Appl. 689:1997;379-386.
7. Emara S., Razee S., Khedr A., Masujima T. Biomed. Chromatogr. 11:1997;42-46.
8. Albertioni F., Rask C., Eksborg S., Poulsen J.H., Pettersson B., Beck O., Schroeder H., Peterson C. Clin. Chem. 42:1996;39-44.
9. Albertioni F., Pettersson B., Beck O., Rask C., Seideman P., Peterson C. J. Chromatogr. Biomed. Appl. 665:1995;163-170.
10. Suzuki T., Hashimoto H., Ichinose N. Fresenius J. Anal. Chem. 351:1995;806-807.
11. Beck O., Seideman P., Wennberg M., Peterson C. Ther. Drug Monit. 13:1991;528-532.
12. Salamoun J., Smrz M., Kiss F., Salamounova A. J. Chromatogr. Biomed. Appl. 63:1987;213-223.
13. Salamoun J., Frantisek J. J. Chromatogr. Biomed. Appl. 51:1986;173-181.
14. Zhang H.N., Wen L.L., Zhang S.W., Ding P.Y. Yaowu. Fenxi. Zahi. 20:2000;401-404.
15. Hirai T., Matsumoto S., Kishi I. J. Chromatogr. Biomed. Appl. 690:1997;267-273.
16. Aboleneen H., Simpson J., Backes D. J. Chromatogr. Biomed. Appl. 681:1996;317-322.
17. Cociglio M., Hillaire-Buys D., Alric C. J. Chromatogr. Biomed. Appl. 674:1995;101-110.
18. Hirai T., Kitamura M., Inoue Y. Yakugaku. Zasshi. 114:1994;602-610.
19. Mader R.M., Rizovski B., Steger G.G., Rainer H., Proprentner R., Kotz R. J. Chromatogr. Biomed. Appl. 124:1993;311-316.
20. Emara S., Razee S., El-Shorbagi A.N., Massujima T. Analyst. 121:1996;183-188.
21. Chakrabarti S.G., Bernstein I.A. Clin. Chem. 15:1969;1157-1161.
22. Kinkade J.M.J., Vogler W.R., Dayton P.G. Biochem. Med. 10:1974;337-350.
23. Sastry C.S.P., Lingeswara-Rao J.S.V.M. Anal. Lett. 29:1996;1763-1778.
24. Ellaithy M.M., El-Tarras M.F., Tadros N.B., Amer M.M. Anal. Lett. 15:1982;981-988.
25. Gandhi R., Khopade A.J., Jain N.K. Indian Drugs. 34:1997;455-458.
26. Fan H.Z., Hou H.X., Ren J.Q., Pan J.H. Fenxi. Huaxue. 24:1996;246.
27. Kovbuz M.O., Felitsin N.M., Khim'yak Y.Z., Zimenkovskii B.S. Farm. Zh. 3:1995;80-83.
28. Malone M.A., Costa Garcia A., Tunon Blanco P., Smyth M.R. Anal. Methods Instrum. 1:1993;164-171.
29. Miranda Ordieres A.J., Costa Garcia A., Fernandez Alvarez J.M., Tunon Blanco P. Anal. Chim. Acta. 233:1990;281-287.
30. Ma Q.L., Yang J.H., Wu X., Huang F., Sun L.M. Anal. Lett. 33:2000;2689-2699.
31. Wang H.Y., Liu L.D., Sun Y., Ma L., Li J. Talanta. 52:2000;201-209.
32. El Walily A.F.M., El-Yazbi F.A., Belal S.F., Abdel-Razak O. Anal. Lett. 30:1997;2029-2043.
33. El-Yazbi F.A., Abdine H.H., Shaalan R.A. J. Pharm. Biomed. Anal. 19:1999;819-827.
34. Das-Gupta V., Stewart K.R., Gunter J.M. J. Pharm. Sci. 72:1983;1470-1471.
35. Zurek G., Karst U. J. Chromatogr. A. 864:1999;191-197.
36. Mansilla A.E., de la Pena A.M., Salinas F., Alanon A., Murillo J.A. J. Agric. Food Chem. 45:1997;172-177.
37. Kelly T.J., Fortune C.R. Int. J. Environ. Anal. Chem. 54:1994;249-263.
38. Imai K., Toyo'oka T., Miyano H. Analyst. 109:1984;1365-1373.
39. Sanchez F.G., Gallardo A.A. Anal. Chim. Acta. 270:1992;45-53.
40. Stein S., Bohlen P., Stone J., Dairman W., Udenfreind S. Arch. Biochem. Biophys. 155:1973;202-212.
41. Weigle M., Blount J.F., Tengi J.P., Czaikowski R.C., Leimgruber W. J. Am. Chem. Soc. 94:1972;4052-4054.
42. Djozan D., Faraj-zadeh M.A. J. Pharm. Biomed. Anal. 10:1992;1063-1067.
43. Blanco C.C., Carretero A.S., Gutiérrez A.F., Ceba M.R. Anal. Lett. 27:1994;1339-1353.
44. Gehring T.A., Rushing L.G., Thompson H.C. J. AOAC Int. 80:1997;751-755.
45. Djozan D., Faraj-zadeh M.A. Chromatographia. 41:1995;568-572.
46. Funk W., Kuepper T., Wirtz A., Netz S. J. Plannar Chromatogr. Mod. TLC. 7:1994;10-13.
47. H.G. Brittain, in: Analytical Profiles of Drug Substances, vol. 5, Academic Press, California, 1986, pp. 284-306.
48. Cairnes D.A., Evans W.E. Ther. Drug Monit. 5:1983;363-366.
49. A. Martin, J. Swarbrick, A. Cammarata, in: Physical Pharmacy, third ed., Lea and Febiger, Washington Square, Philadelphia, USA, 1983, pp. 352-394.
50. Garrett E.R., Carper R.F. J. Am. Pharm. Assoc. 44:1955;515.
51. de Silva J.A.F., Stonjny N. Anal. Chem. 47:1975;714-718.
52. Miller J.N. Analyst. 113:1991;3-14.
53. Gallelli J.F., Yokoyama G. J. Pharm. Sci. 56:1967;387-389.
54. Bolton S. Pharmaceutical Statistics. 1984;218-225 Marcel Dekker, New York.
55. A.C. Moffat, J.V. Jackson, M.S. Moss, B. Widdop, Clarke's Isolation and Identification of Drugs, second ed., London, 1986, p. 756.
56. Djerassi L. Cancer Chem. Rep. 6:1975;3-6.