메뉴 건너뛰기




Volumn 99, Issue 2, 2006, Pages 435-449

Reduction of anabolic signals and alteration of osteoblast nuclear morphology in microgravity

Author keywords

bcl2; Cytometry; fgf 2; Growth regulation; Microgravity; Morphometry; Photometry

Indexed keywords

CYCLINE; CYCLOOXYGENASE 2; CYTOPLASM PROTEIN; FIBROBLAST GROWTH FACTOR 2; MITOGENIC AGENT; MYC PROTEIN; OSTEOCALCIN; PHOSPHOLIPASE A2; PROTEIN BAX; PROTEIN BCL 2; TRANSFORMING GROWTH FACTOR BETA;

EID: 33748938686     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.20883     Document Type: Article
Times cited : (47)

References (43)
  • 1
    • 0033548714 scopus 로고    scopus 로고
    • Arachidonic acid in platelet microparticles upregulates cyclooxygenase-2-dependent prostaglandin formation via a protein kinase C/mitogen-activated protein kinase-dependent pathway
    • Barry OP, Kazanietz MG, Pratico D, FitzGerald GA. 1999. Arachidonic acid in platelet microparticles upregulates cyclooxygenase-2-dependent prostaglandin formation via a protein kinase C/mitogen-activated protein kinase-dependent pathway. J Biol Chem 274:7545-7556.
    • (1999) J Biol Chem , vol.274 , pp. 7545-7556
    • Barry, O.P.1    Kazanietz, M.G.2    Pratico, D.3    FitzGerald, G.A.4
  • 2
    • 0030028947 scopus 로고    scopus 로고
    • Cytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates the anchorage-dependent expression of cyclin D1
    • Bohmer RM, Scharf E, Assoian RK. 1996. Cytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates the anchorage-dependent expression of cyclin D1. Mol Biol Cell 7:101-111.
    • (1996) Mol Biol Cell , vol.7 , pp. 101-111
    • Bohmer, R.M.1    Scharf, E.2    Assoian, R.K.3
  • 4
    • 0025765080 scopus 로고
    • Growth factors and cytokines in bone cell metabolism
    • Canalis E, McCarthy TL, Centrella M. 1991. Growth factors and cytokines in bone cell metabolism. Annu Rev Med 42:17-24.
    • (1991) Annu Rev Med , vol.42 , pp. 17-24
    • Canalis, E.1    McCarthy, T.L.2    Centrella, M.3
  • 5
    • 0031900295 scopus 로고    scopus 로고
    • Gene expression related to the differentiation of osteoblastic cells is altered by microgravity
    • Carmeliet G, Nys G, Stockmans I, Bouillon R. 1998. Gene expression related to the differentiation of osteoblastic cells is altered by microgravity. Bone 22:1398-1438.
    • (1998) Bone , vol.22 , pp. 1398-1438
    • Carmeliet, G.1    Nys, G.2    Stockmans, I.3    Bouillon, R.4
  • 6
    • 0031904354 scopus 로고    scopus 로고
    • Osteoblasts induce osteopontin expression in response to attachment on fibronectin: Demonstration of a common role for integrin receptors in the signal transduction processes of cell attachment and mechanical stimulation
    • Carvalho RS, Schaffer JL, Gerstenfeld LC. 1998. Osteoblasts induce osteopontin expression in response to attachment on fibronectin: Demonstration of a common role for integrin receptors in the signal transduction processes of cell attachment and mechanical stimulation. J Cell Biochem 70:376-390.
    • (1998) J Cell Biochem , vol.70 , pp. 376-390
    • Carvalho, R.S.1    Schaffer, J.L.2    Gerstenfeld, L.C.3
  • 8
    • 0034028838 scopus 로고    scopus 로고
    • Fas/APO-1 protein is increased in spaceflown lymphocytes (Jurkat)
    • Cubano LA, Lewis ML. 2000. Fas/APO-1 protein is increased in spaceflown lymphocytes (Jurkat). Exp Gerontol 35:389-400.
    • (2000) Exp Gerontol , vol.35 , pp. 389-400
    • Cubano, L.A.1    Lewis, M.L.2
  • 12
    • 0032881990 scopus 로고    scopus 로고
    • Geometric control of switching between growth, apoptosis, and differentiation during angiogenesis using micropatterned substrates
    • Dike LE, Chen CS, Mrksich M, Tien J, Whitesides GM, Ingber DE. 1999. Geometric control of switching between growth, apoptosis, and differentiation during angiogenesis using micropatterned substrates. In Vitro Cell Dev Biol Anim 35:441-448.
    • (1999) In Vitro Cell Dev Biol Anim , vol.35 , pp. 441-448
    • Dike, L.E.1    Chen, C.S.2    Mrksich, M.3    Tien, J.4    Whitesides, G.M.5    Ingber, D.E.6
  • 13
    • 0030579070 scopus 로고    scopus 로고
    • Gravitational loading of a simulated launch alters mRNA expression in osteoblasts
    • Fitzgerald J, Hughes-Fulford M. 1996. Gravitational loading of a simulated launch alters mRNA expression in osteoblasts. Exp Cell Res 228:168-171.
    • (1996) Exp Cell Res , vol.228 , pp. 168-171
    • Fitzgerald, J.1    Hughes-Fulford, M.2
  • 14
    • 0032968537 scopus 로고    scopus 로고
    • Mechanically induced c-fos expression is mediated by cAMP in MC3T3-E1 osteoblasts
    • Fitzgerald J, Hughes-Fulford M. 1999. Mechanically induced c-fos expression is mediated by cAMP in MC3T3-E1 osteoblasts. Faseb J 13:553-557.
    • (1999) Faseb J , vol.13 , pp. 553-557
    • Fitzgerald, J.1    Hughes-Fulford, M.2
  • 15
    • 85047682137 scopus 로고    scopus 로고
    • Prostaglandin E2-induced up-regulation of c-fos messenger ribonucleic acid is primarily mediated by 3′,5′-cyclic adenosine monophosphate in MC3T3-E1 osteoblasts
    • Fitzgerald J, Dietz TJ, Hughes-Fulford M. 2000. Prostaglandin E2-induced up-regulation of c-fos messenger ribonucleic acid is primarily mediated by 3′,5′-cyclic adenosine monophosphate in MC3T3-E1 osteoblasts. Endocrinology 141:291-298.
    • (2000) Endocrinology , vol.141 , pp. 291-298
    • Fitzgerald, J.1    Dietz, T.J.2    Hughes-Fulford, M.3
  • 17
    • 0029998565 scopus 로고    scopus 로고
    • Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo
    • Forwood MR. 1996. Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo. J Bone Miner Res 11:1688-1693.
    • (1996) J Bone Miner Res , vol.11 , pp. 1688-1693
    • Forwood, M.R.1
  • 18
    • 0031593465 scopus 로고    scopus 로고
    • Localisation of prostaglandin endoperoxide H synthase (PGHS)-1 and PGHS-2 in bone following mechanical loading in vivo
    • Forwood MR, Kelly WL, Worth NF. 1998. Localisation of prostaglandin endoperoxide H synthase (PGHS)-1 and PGHS-2 in bone following mechanical loading in vivo. Anat Rec 252:580-586.
    • (1998) Anat Rec , vol.252 , pp. 580-586
    • Forwood, M.R.1    Kelly, W.L.2    Worth, N.F.3
  • 19
    • 0033671236 scopus 로고    scopus 로고
    • Selected contribution: A three-dimensional model for assessment of in vitro toxicity in balaena mysticetus renal tissue
    • Goodwin TJ, Coate-Li L, Linnehan RM, Hammond TG. 2000. Selected contribution: A three-dimensional model for assessment of in vitro toxicity in balaena mysticetus renal tissue. J Appl Physiol 89:2508-2517.
    • (2000) J Appl Physiol , vol.89 , pp. 2508-2517
    • Goodwin, T.J.1    Coate-Li, L.2    Linnehan, R.M.3    Hammond, T.G.4
  • 20
    • 0034814966 scopus 로고    scopus 로고
    • MAPK and SRC-kinases control EGR-1 and NF-kappa B inductions by changes in mechanical environment in osteoblasts
    • Granet C, Boutahar N, Vico L, Alexandre C, Lafage-Proust MH. 2001. MAPK and SRC-kinases control EGR-1 and NF-kappa B inductions by changes in mechanical environment in osteoblasts. Biochem Biophys Res Commun 284:622-631.
    • (2001) Biochem Biophys Res Commun , vol.284 , pp. 622-631
    • Granet, C.1    Boutahar, N.2    Vico, L.3    Alexandre, C.4    Lafage-Proust, M.H.5
  • 21
    • 0028809444 scopus 로고
    • Shape changes of osteoblastic cells under gravitational variations during parabolic flight-Relationship with PGE2 synthesis
    • Guignandon A, Vico L, Alexandre C, Lafage-Proust MH. 1995. Shape changes of osteoblastic cells under gravitational variations during parabolic flight-Relationship with PGE2 synthesis. Cell Struct Funct 20:369-375.
    • (1995) Cell Struct Funct , vol.20 , pp. 369-375
    • Guignandon, A.1    Vico, L.2    Alexandre, C.3    Lafage-Proust, M.H.4
  • 23
    • 0037214222 scopus 로고    scopus 로고
    • A short pulse of mechanical force induces gene expression and growth in MC3T3-E1 osteoblasts via an ERK 1/2 pathway
    • Hatton JP, Pooran M, Li CF, Luzzio C, Hughes-Fulford M. 2003. A short pulse of mechanical force induces gene expression and growth in MC3T3-E1 osteoblasts via an ERK 1/2 pathway. J Bone Miner Res 18:58-66.
    • (2003) J Bone Miner Res , vol.18 , pp. 58-66
    • Hatton, J.P.1    Pooran, M.2    Li, C.F.3    Luzzio, C.4    Hughes-Fulford, M.5
  • 24
    • 0032563289 scopus 로고    scopus 로고
    • Stimulation of p38 phosphorylation and activity by arachidonic acid in HeLa cells, HL60 promyelocytic leukemic cells, and human neutrophils. Evidence for cell type-specific activation of mitogen-activated protein kinases
    • Hu CS, Huang ZH, Bilney A, Costabile M, Murray AW, Rathjen DA, Der CJ, Ferrante A. 1998. Stimulation of p38 phosphorylation and activity by arachidonic acid in HeLa cells, HL60 promyelocytic leukemic cells, and human neutrophils. Evidence for cell type-specific activation of mitogen-activated protein kinases. J Biol Chem 273:19277-19282.
    • (1998) J Biol Chem , vol.273 , pp. 19277-19282
    • Hu, C.S.1    Huang, Z.H.2    Bilney, A.3    Costabile, M.4    Murray, A.W.5    Rathjen, D.A.6    Der, C.J.7    Ferrante, A.8
  • 25
    • 0021083906 scopus 로고
    • Effect of dibutyryl cyclic AMP on collagen synthesis in a clonal osteoblast-like cell line derived from newborn mouse calvaria
    • Hiramatsu M, Ikeda E, Kashimata M, Minami N, Kodama H, Sudo H, Kumegawa M. 1983. Effect of dibutyryl cyclic AMP on collagen synthesis in a clonal osteoblast-like cell line derived from newborn mouse calvaria. J Biochem (Tokyo) 94:1353-1358.
    • (1983) J Biochem (Tokyo) , vol.94 , pp. 1353-1358
    • Hiramatsu, M.1    Ikeda, E.2    Kashimata, M.3    Minami, N.4    Kodama, H.5    Sudo, H.6    Kumegawa, M.7
  • 26
    • 13444276396 scopus 로고    scopus 로고
    • Signal transduction and mechanical stress
    • Hughes-Fulford M. 2004. Signal transduction and mechanical stress. Sci STKE 2004:RE12.
    • (2004) Sci STKE , vol.2004
    • Hughes-Fulford, M.1
  • 27
    • 0029929359 scopus 로고    scopus 로고
    • Effects of microgravity on osteoblast growth activation
    • Hughes-Fulford M, Lewis ML. 1996. Effects of microgravity on osteoblast growth activation. Exp Cell Res 224:103-109.
    • (1996) Exp Cell Res , vol.224 , pp. 103-109
    • Hughes-Fulford, M.1    Lewis, M.L.2
  • 28
    • 0026486468 scopus 로고
    • Effect of dexamethasone on proliferating osteoblasts: Inhibition of prostaglandin E2 synthesis, DNA synthesis, and alterations in actin cytoskeleton
    • Hughes-Fulford M, Appel R, Kumegawa M, Schmidt J. 1992. Effect of dexamethasone on proliferating osteoblasts: Inhibition of prostaglandin E2 synthesis, DNA synthesis, and alterations in actin cytoskeleton. Exp Cell Res 203:150-156.
    • (1992) Exp Cell Res , vol.203 , pp. 150-156
    • Hughes-Fulford, M.1    Appel, R.2    Kumegawa, M.3    Schmidt, J.4
  • 29
    • 0029559549 scopus 로고
    • Cell shape, cytoskeletal mechanics, and cell cycle control in angiogenesis
    • Ingber DE, Prusty D, Sun Z, Betensky H, Wang N. 1995. Cell shape, cytoskeletal mechanics, and cell cycle control in angiogenesis. J Biomech 28:1471-1484.
    • (1995) J Biomech , vol.28 , pp. 1471-1484
    • Ingber, D.E.1    Prusty, D.2    Sun, Z.3    Betensky, H.4    Wang, N.5
  • 30
    • 0033519346 scopus 로고    scopus 로고
    • Import(ance) of growth factors in(to) the nucleus
    • Keresztes M, Boonstra J. 1999. Import(ance) of growth factors in(to) the nucleus. J Cell Biol 145:421-424.
    • (1999) J Cell Biol , vol.145 , pp. 421-424
    • Keresztes, M.1    Boonstra, J.2
  • 32
    • 0035432020 scopus 로고    scopus 로고
    • DNA microarray reveals altered cytoskeletal gene expression in space-flown leukemic T lymphocytes (Jurkat)
    • Lewis ML, Cubano LA, Zhao B, Dinh HK, Pabalan JG, Piepmeier EH, Bowman PD. 2001. cDNA microarray reveals altered cytoskeletal gene expression in space-flown leukemic T lymphocytes (Jurkat). Faseb J 15: 1783-1785.
    • (2001) Faseb J , vol.15 , pp. 1783-1785
    • Lewis, M.L.1    Cubano, L.A.2    Zhao, B.3    Dinh, H.K.4    Pabalan, J.G.5    Piepmeier, E.H.6    Bowman, P.D.7
  • 37
    • 0037272440 scopus 로고    scopus 로고
    • A feature set for cytometry on digitized microscopic images
    • Rodenacker K, Bengtsson E. 2003. A feature set for cytometry on digitized microscopic images. Anal Cell Pathol 25:1-36.
    • (2003) Anal Cell Pathol , vol.25 , pp. 1-36
    • Rodenacker, K.1    Bengtsson, E.2
  • 38
    • 0038137520 scopus 로고    scopus 로고
    • The role of the cytoskeleton in mechanotransduction in human osteoblast-like cells
    • Rosenberg N. 2003. The role of the cytoskeleton in mechanotransduction in human osteoblast-like cells. Hum Exp Toxicol 22:271-274.
    • (2003) Hum Exp Toxicol , vol.22 , pp. 271-274
    • Rosenberg, N.1
  • 39
    • 0027965860 scopus 로고
    • Regulation of bFGF gene expression and subcellular distribution of bFGF protein in adrenal medullary cells
    • Stachowiak MK, Moffett J, Joy A, Puchacz E, Florkiewicz R, Stachowiak EK. 1994. Regulation of bFGF gene expression and subcellular distribution of bFGF protein in adrenal medullary cells. J Cell Biol 127:203-223.
    • (1994) J Cell Biol , vol.127 , pp. 203-223
    • Stachowiak, M.K.1    Moffett, J.2    Joy, A.3    Puchacz, E.4    Florkiewicz, R.5    Stachowiak, E.K.6
  • 40
    • 0034612094 scopus 로고    scopus 로고
    • Effects of long-term microgravity exposure on cancellous and cortical weight-bearing bones of cosmonauts
    • Vico L, Collet P, Guignandon A, Lafage-Proust MH, Thomas T, Rehaillia M, Alexandre C. 2000. Effects of long-term microgravity exposure on cancellous and cortical weight-bearing bones of cosmonauts. Lancet 355:1607-1611.
    • (2000) Lancet , vol.355 , pp. 1607-1611
    • Vico, L.1    Collet, P.2    Guignandon, A.3    Lafage-Proust, M.H.4    Thomas, T.5    Rehaillia, M.6    Alexandre, C.7
  • 41
    • 0029996726 scopus 로고    scopus 로고
    • Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation
    • Wang J, Walsh K. 1996. Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation. Science 273:359-361.
    • (1996) Science , vol.273 , pp. 359-361
    • Wang, J.1    Walsh, K.2
  • 42
    • 0020728979 scopus 로고
    • Effect of spaceflight on periosteal bone formation in rats
    • Wronski TJ, Morey ER. 1983. Effect of spaceflight on periosteal bone formation in rats. Am J Physiol 244: R305-R309.
    • (1983) Am J Physiol , vol.244
    • Wronski, T.J.1    Morey, E.R.2
  • 43
    • 0022775071 scopus 로고
    • Characterization of chromatin distribution in cell nuclei
    • Young IT, Verbeek PW, Mayall BH. 1986. Characterization of chromatin distribution in cell nuclei. Cytometry 7: 467-474.
    • (1986) Cytometry , vol.7 , pp. 467-474
    • Young, I.T.1    Verbeek, P.W.2    Mayall, B.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.