Prostaglandin E2-induced up-regulation of c-fos messenger ribonucleic acid is primarily mediated by 3′,5′-cyclic adenosine monophosphate in MC3T3-E1 osteoblasts

Endocrinology

Volumn 141, Issue 1, 2000, Pages 291-298

  Fitzgerald, Jamie ^c   Dietz, Thomas J ^d   Hughes Fulford, Millie ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; MESSENGER RNA; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROSTAGLANDIN E2; PROTEIN C FOS; PROTEIN KINASE C INHIBITOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; DOWN REGULATION; ENZYME ACTIVITY; GENE ACTIVATION; GENE DELETION; GENE INDUCTION; GENETIC TRANSFECTION; HORMONAL REGULATION; LYMPHOMA CELL; NONHUMAN; ONCOGENE C FOS; OSTEOBLAST; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECOND MESSENGER; TUMOR GROWTH; ANIMAL; BIOSYNTHESIS; CELL LINE; CERCOPITHECUS; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; MOUSE; NASA DISCIPLINE CELL BIOLOGY; NASA PROGRAM FUNDAMENTAL SPACE BIOLOGY; NON-NASA CENTER; ONCOGENE; OSTEOCYTE; PHYSIOLOGY; UPREGULATION; VERO CELL;

NASA DISCIPLINE CELL BIOLOGY; NASA PROGRAM FUNDAMENTAL SPACE BIOLOGY; NON-NASA CENTER;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DINOPROSTONE; GENES, FOS; GENES, REPORTER; HUMANS; MICE; OSTEOCYTES; PROMOTER REGIONS (GENETICS); PROTEIN KINASE C; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFECTION; UP-REGULATION; VERO CELLS;

EID: 85047682137     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.141.1.7271     Document Type: Article

References (56)

1. Regulation of bone formation
2. Effect of prostaglandins E2 and F2a on biosynthesis of collagen
3. Platelet-derived growth factor stimulates bone resorption via a prostaglandin-mediated mechanism
4. The effects of prostaglandin E2 in growing rats: Increased metaphyseal hard tissue and cortico-endosteal bone formation
5. 2
6. Increased metaphyseal hard tissue mass in growing long bone with prostaglandin E2 administration
7. The role of prostaglandins in bone in vivo
8. Osteoblastic and fibroblastic PGE: In vivo effects of indomethacin and mechanical force
9. Inhibition of bone formation during space flight
10. Effect of spaceflight on periosteal bone formation in rats
11. Review of the biological effects of weightlessness on the human endocrine system
12. Effects of microgravity on osteoblast growth activation
13. Epidermal growth factor-induced cell rounding is sensitive to simulated microgravity
14. Suppressed PHA activation of T lymphocytes in simulated microgravity is restored by direct activation of protein kinase C
15. Microgravity decreases c-fos induction and serum response element activity
16. Growth factor-induced signal transduction in adherent mammalian cells is sensitive to gravity
17. Microgravity alters protein phosphorylation changes during initiation of sea urchin sperm motility
18. Activation and proliferation of lymphocytes and other mammalian cells in microgravity
19. The distribution of protein kinase C in human leukocytes is altered in microgravity
20. The kinetics of translocation and cellular quantity of protein linase C in human leukocytes are modified during spaceflight
21. Prostaglandin regulation of gene expression and growth in normal and malignant tissues
22. Osteoblasts are target cells for transformation in c-fos transgenic mice
23. Pleitropic effects of a null mutation in the c-fos proto-oncogene
24. Bone and haematopoietic defects in mice lacking c-fos
25. Deregulated c-fos expression interferes with normal bone development in transgenic mice
26. c-fos: A key regulator of osteoclast-macrophage lineage de-termination and bone remodeling
27. c-fos and bone loss: A proto-oncogene regulates osteoclast lineage determination
28. Arachidonic acid increases c-fos and Egr-1 mRNA in 3T3 fibroblasts by formation of prostaglandin E2 and activation of protein kinase C
29. PGE2 induces c-fos expression by a cAMP-independent mechanism in glomerular mesangial cells
30. Parathyroid hormone induces c-fos and c-jun messenger RNA in rat osteoblastic cells
31. The effects of prostaglandin E2, parathyroid hormone, and epidermal growth factor on mitogenesis, signaling, and primary response genes in UMR 106-101 osteoblast-like cells
32. In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria
33. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
34. An altered repertoire of fos/jun (AP-1) at the onset of replicative sensecence
35. c-fos sequences necessary for basal expression and induction by epidermal growth factor, 12-O-tetradecanoyl phorbol-13-acetate, and the calcium ionophore
36. 2 synthesis, DNA synthesis and alterations in actin cytoskeleton
37. Forskolin: Unique diterpene activator of adenylate cyclase in membranes and intact cells
38. 2+ -sensitive, phospholipid-dependent protein kinase activity in phorbol ester-treated 3T3 cells
39. Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C
40. Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesised selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamid (H-89), of PC12D pheochromocytoma cells
41. Differences in the forskolin activation of adenylate cyclases in wild-type and variant lymphoma cells
42. Cross-talk regulation between cyclic AMP production and phosphoinositide hydrolysis induced by prostaglandin E2 in osteoblast-like cells
43. Bombesin induces c-fos and c-myc expression in quiescent Swiss 3T3 cells. Comparative study with other mitogens
44. Dissociation of c-fos induction from protein kinase C-independent mitogenesis in Swiss 3T3 cells
45. Induction of c-fos and c-myc mRNA by epidermal growth factor and calcium ionophore is cAMP dependent
46. Multiple synergistic signal transduction pathways regulate c-fos expression in Swiss 3T3 cells: The role of cAMP
47. Early signals in the mitogenic response
48. Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity
49. Prostaniod biosynthesis and mechanisms of action
50. Gene expression in osteoblastic cells
51. Retinoic acid modulation of mRNA levels in malignant, nontransformed and immortalized osteoblasts
52. Repression of c-fos transcription is mediated through p67SRF bound to the SRE
53. Negative regulation of serum-responsive enhancer elements
54. Trans-repression of the mouse c-fos promoter: A novel mechanism of Fos-mediated trans-regulation
55. Functional dissection of the human c-fos promoter