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Journal of Organic Chemistry

Volumn 66, Issue 10, 2001, Pages 3474-3483

Synthesis of tricyclic indole-2-caboxylic acids as potent NMDA-glycine antagonists

(3) Katayama, S a Ae, N a Nagata, R a

a DAINIPPON SUMITOMO PHARMA CO LTD (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

RADIO LIGAND BINDING ASSAY;

HYDROLYSIS; OPTICAL RESOLVING POWER; PURIFICATION; SYNTHESIS (CHEMICAL);

CARBOXYLIC ACIDS;

2 INDOLECARBOXYLIC ACID; 7 CHLORO 3 AMINOCARBONYLMETHYL 1,3,4,5 TETRAHYDROBENZ[CD]INDOLE 2 CARBOXYLIC ACID; CARBOXYLIC ACID DERIVATIVE; GLYCINE RECEPTOR ANTAGONIST; INDOLE DERIVATIVE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; TOLUENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CHIRALITY; CHROMATOGRAPHY; CYCLIZATION; DRUG BINDING; DRUG POTENCY; DRUG SYNTHESIS; HYDROLYSIS; IODINATION; ISOMERISM; PURIFICATION; REACTION ANALYSIS;

ANIMALS; BINDING SITES; GLYCINE; GLYCINE AGENTS; HETEROCYCLIC COMPOUNDS, 3-RING; HUMANS; INDOLES; N-METHYLASPARTATE; RADIOLIGAND ASSAY; RECEPTORS, N-METHYL-D-ASPARTATE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035906471 PISSN: 00223263 EISSN: None Source Type: Journal
DOI: 10.1021/jo010002h Document Type: Article

Times cited : (53)

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