Increase in interleukin-6 following arterial injury is related to insulin resistance, the -174G→C polymorphism and complex plaque morphology

International Journal of Immunogenetics

Volumn 33, Issue 5, 2006, Pages 347-354

  Marso, S P ^a,c   House, J A ^a   Hopkins, P J ^b  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b Clinical Reference Laboratory   (United States)

^c SAINT LUKE S MID AMERICA HEART INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CREATINE KINASE MB; HEMOGLOBIN A1C; INSULIN; INTERLEUKIN 6; LIPID; TROPONIN I;

ADULT; AGED; ARTERY INJURY; ARTICLE; ATHEROSCLEROTIC PLAQUE; BLOOD SAMPLING; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; DIABETES MELLITUS; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HOMEOSTASIS; HUMAN; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; MUSCLE NECROSIS; PERCUTANEOUS CORONARY INTERVENTION; PREDICTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; WAIST CIRCUMFERENCE;

ANGIOPLASTY, BALLOON, CORONARY; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; BIOLOGICAL MARKERS; CORONARY ARTERIOSCLEROSIS; CORONARY ARTERY DISEASE; CORONARY VESSELS; FEMALE; HUMANS; INSULIN RESISTANCE; INTERLEUKIN-6; MALE; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); PROMOTER REGIONS, GENETIC;

EID: 33748897307     PISSN: 17443121     EISSN: 1744313X     Source Type: Journal    
DOI: 10.1111/j.1744-313X.2006.00622.x     Document Type: Article

References (37)

1. ACC/AHA. (1988) Guidelines for percutaneous transluminal coronary angioplasty. A report of the American College of Cardiology/American Heart Association Task Force on Assessment of Diagnostic and Therapeutic Cardiovascular Procedures (Subcommittee on Percutaneous Transluminal Coronary Angioplasty). Journal of the American College of Cardiology, 12, 529.
2. Azar, R., McKay, R., Kiernan, F., Seecharran, B., Feng, Y., Fram, D. et al. (1997) Coronary angioplasty induces a systemic inflammatory response. American Journal of Cardiology, 80, 1476.
3. Bennermo, M., Held, C., Stemme, S., Ericsson, C.G., Silveira, A., Green, F. et al. (2004) Genetic predisposition of the interleukin-6 response to inflammation: implications for a variety of major diseases? Clinical Chemistry, 50, 2136.
4. Biasucci, L.M., Liuzzo, G., Fantuzzi, G., Caligiuri, G., Rebuzzi, A.G., Ginnetti, F. et al. (1999) Increasing levels of interleukin (IL)-1Ra and IL-6 during the first 2 days of hospitalization in unstable angina are associated with increased risk of in-hospital coronary events. Circulation, 99, 2079.
5. Biasucci, L.M., Vitelli, A., Liuzzo, G., Altamura, S., Caligiuri, G., Monaco, C. et al. (1996) Elevated levels of interleukin-6 in unstable angina. Circulation, 94, 874.
6. Biswas, P., Delfanti, F., Bernasconi, S., Mengozzi, M., Cota, M., Polentarutti, N. et al. (1998) Interleukin-6 induces monocyte chemotactic protein-1 in peripheral blood mononuclear cells and in the U937 cell line. Blood, 91, 258.
7. Braunwald, E., Antman, E.M., Beasley, J.W., Califf, R.M., Cheitlin, M.D., Hochman, J.S. et al. (2002) ACC/AHA 2002 Guideline Update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction-summary article: a report of the American College of Cardiology/American Heart Association task force on practice guidelines (Committee on the Management of Patients with Unstable Angina. JAM Coll Cardiol, 40, 1366.
8. Brull, D.J., Leeson, C.P., Montgomery, H.E., Mullen, M., deDivitiis, M., Humphries, S.E. et al. (2002) The effect of the interleukin-6 -174G > C promoter gene polymorphism on endothelial function in healthy volunteers. European Journal of Clinical Investigations, 32, 153.
9. Burzotta, F., Iacoviello, L., Di Castelnuovo, A., Glieca, F., Luciani, N., Zamparelli, R. et al. (2001) Relation of the -174 G/C polymorphism of interleukin-6 to interleukin-6 plasma levels and to length of hospitalization after surgical coronary revascularization. American Journal of Cardiology, 88, 1125.
10. Cusack, M.R., Marber, M.S., Lambiase, P.D., Bucknall, C.A. & Redwood, S.R. (2002) Systemic inflammation in unstable angina is the result of myocardial necrosis. Journal of the American College of Cardiology, 39, 1917.
11. Fishman, D., Faulds, G., Jeffery, R., Mohamed-Ali, V., Yudkin, J.S., Humphries, S. et al. (1998) The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. Journal of Clinical Investigations, 102, 1369.
12. Friedewald, W.T., Levy, R.I. & Fredrickson, D.S. (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clinical Chemistry, 18, 499.
13. Galis, Z.S., Muszynski, M., Sukhova, G.K., Simon-Morrissey, E., Unemori, E.N., Lark, M.W. et al. (1994) Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion. Circulation Research, 75, 181.
14. Goldberg, A., Zinder, O., Zdorovyak, A., Diamond, E., Lischinsky, S., Gruberg, L. et al. (2003) Diagnostic coronary angiography induces a systemic inflammatory response in patients with stable angina. American Heart Journal, 146, 819.
15. Hamanak, R., Kohno, K., Seguchi, T., Okamura, K., Morimoto, T., Onon, M. et al. (1992) Induction of low-density lipoprotein receptor and transcription factor SP-1 by tumor necrosis factor in human vascular endothelial cells. Journal of Biological Chemistry, 267, 13160.
16. Henrichot, E., Juge-Aubry, C.E., Pernin, A., Pache, J.C., Velebit, V., Dayer, J.M et al. (2005) Production of chemokines by perivascular adipose tissue: a role in the pathogenesis of atherosclerosis? Arteriosclerosis, Thrombosis, and Vascular Biology, 25, 2594.
17. Humphries, S.E., Luong, L.A., Ogg, M.S., Hawe, E. & Miller, G.J. (2001) The interleukin-6 -174 G/C promoter polymorphism is associated with risk of coronary heart disease and systolic blood pressure in healthy men. European Heart Journal, 22, 2243.
18. Ikeda, U., Ito, T. & Shimada, K. (2001) Interleukin-6 and acute coronary syndrome. Clinical Cardiology, 24, 701.
19. Inoue, T., Kato, T., Uchida, T., Sakuma, M., Nakajima, A., Shibazaki, M. et al. (2005) Local release of C-reactive protein from vulnerable plaque or coronary arterial wall injured by stenting. Journal of the American College of Cardiology, 46, 239.
20. Jenny, N.S., Tracy, R.P., Ogg, M.S., Luong le, A., Kuller, L.H., Arnold, A.M. et al. (2002) In the elderly, interleukin-6 plasma levels and the -174G > C polymorphism are associated with the development of cardiovascular disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 22, 2066.
21. Jones, K.G., Brull, D.J., Brown, L.C., Sian, M., Greenhalgh, R.M., Humphries, S.E. et al. (2001) Interleukin-6 (IL-6) and the prognosis of abdominal aortic aneurysms. Circulation, 103, 2260.
22. Lindmark, E., Diderholm, E., Wallentin, L. & Siegbahn, A. (2001) Relationship between interleukin 6 and mortality in patients with unstable coronary artery disease: effects of an early invasive or noninvasive strategy. JAMA, 286, 2107.
23. Liuzzo, G., Buffon, A., Biasucci, L.M., Gallimore, J.R., Caligiuri, G., Vitelli, A. et al. (1998) Enhanced inflammatory response to coronary angioplasty in patients with severe unstable angina. Circulation, 98, 2370.
24. Loppnow, H. & Libby, P. (1989) Adult human vascular endothelial cells express the IL6 gene differentially in response to LPS or IL1. Cell Immunology, 122, 493.
25. McGlinchey, P.G., Spence, M.S., Patterson, C.C., Allen, A.R., Murphy, G., Savage, D.A. et al. (2004) Cytokine gene polymorphisms in ischaemic heart disease: investigation using family-based tests of association. Journal of Molecular Medicine, 82, 756.
26. Mostafazadeh, A., Herder, C., Haastert, B., Hanifi-Moghaddam, P., Schloot, N., Koenig, W. et al. (2005) Association of humoral immunity to human Hsp60 with the IL-6 gene polymorphism C-174G in patients with type 2 diabetes and controls. Hormone and Metabolic Research, 37, 257.
27. Nauck, M., Winkelmann, B.R., Hoffmann, M.M., Bohm, B.O., Wieland, H. & Marz, W. (2002) The interleukin-6 G (-174)C promoter polymorphism in the LURIC cohort: no association with plasma interleukin-6, coronary artery disease, and myocardial infarction. Journal of Molecular Medicine, 80, 507.
28. NCEP (2002) Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation, 106, 3143.
29. Neumann, F.J., Ott, I., Marx, N., Luther, T., Kenngott, S., Gawaz, M. et al. (1997) Effect of human recombinant interleukin-6 and interleukin-8 on monocyte procoagulant activity. Arteriosclerosis, Thrombosis, and Vascular Biology, 17, 3399.
30. Papanicolaou, D.A. & Vgontzas, A.N. (2000) Interleukin-6: the endocrine cytokine. Journal of Clinical Endocrinology and Metabolism, 85, 1331.
31. Pradhan, A.D., Manson, J.E., Rifai, N., Buring, J.E. & Ridker, P.M. (2001) C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA, 286, 327.
32. Ridker, P.M., Rifai, N., Stampfer, M.J. & Hennekens, C.H. (2000) Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men. Circulation, 101, 1767.
33. Ross, R. (1999) Atherosclerosis - an inflammatory disease. New England Journal of Medicine, 340, 115.
34. Rus, H.G., Vlaicu, R. & Niculescu, F. (1996) Interleukin-6 and interleukin-8 protein and gene expression in human arterial atherosclerotic wall. Atherosclerosis, 127, 263.
35. Seino, Y., Ikeda, U., Ikeda, M., Yamamoto, K., Misawa, Y., Hasegawa, T. et al. (1994) Interleukin 6 gene transcripts are expressed in human atherosclerotic lesions. Cytokine, 6, 87.
36. Sie, M.P., Sayed-Tabatabaei, F.A., Oei, H.H., Uitterlinden, A.G., Pols, H.A., Hofman, A. et al. (2006) Interleukin 6 -174 G/C promoter polymorphism and risk of coronary heart disease: results from the rotterdam study and a meta-analysis. Arteriosclerosis, Thrombosis, and Vascular Biology, 26, 212.
37. Yudkin, J.S., Kumari, M., Humphries, S.E. & Mohamed-Ali, V. (2000) Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link? Atherosclerosis, 148, 209.