Relationship between interleukin 6 and mortality in patients with unstable coronary artery disease: Effects of an early invasive or noninvasive strategy

JAMA

Volumn 286, Issue 17, 2001, Pages 2107-2113

  Lindmark, E ^a   Diderholm, E ^a   Wallentin, L ^a   Siegbahn, A ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; C REACTIVE PROTEIN; DALTEPARIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FIBRINOGEN; HEPARIN; INTERLEUKIN 6; PLACEBO;

ADULT; AGED; ANGIOCARDIOGRAPHY; ARTICLE; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE MARKER; DOUBLE BLIND PROCEDURE; ELECTROCARDIOGRAPHY; FEMALE; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; SCANDINAVIA; STATISTICAL ANALYSIS; UNSTABLE ANGINA PECTORIS;

EID: 0035824178     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.286.17.2107     Document Type: Article

References (24)

1. Atherosclerosis: An inflammatory disease
2. Prognostic influence of increased fibrinogen and C-reactive protein levels in unstable coronary artery disease
3. Elevation of C-reactive protein in "active" coronary artery disease
4. Elevated levels of interleukin-6 in unstable angina
5. Increasing levels of interleukin (IL)-1 Ra and IL-6 during the first 2 days of hospitalization in unstable angina are associated with increased risk of in-hospital coronary events
6. Circulating levels of IL-1 β, a prothrombotic cytokine, are elevated in unstable angina vs stable angina
7. Inflammatory status as a main determinant of outcome in patients with unstable angina, independent of coagulation activation and endothelial cell function
8. Markers of myocardial damage and inflammation in relation to long-term mortality in unstable coronary artery disease
9. Creactive protein: Relation to total mortality, cardiovascular mortality and cardiovascular risk factors in men
10. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men
11. C-Reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: Results from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984 to 1992
12. Creactive protein and other markers of inflammation in the prediction of cardiovascular disease in women
13. Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly
14. The biological effects of interleukin 6
15. Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men
16. Long-term low-molecular-mass heparin in unstable coronary-artery disease: FRISC II prospective randomised multicentre study
17. Invasive compared with non-invasive treatment in unstable coronary-artery disease: FRISC II prospective randomised multicentre study
18. Outcome at 1 year after an invasive compared with a non-invasive strategy in unstable coronary-artery disease
19. Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: Potential implications for inflammation and plaque instability
20. Inflammatory markers of coronary risk
21. Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the Studies of Left Ventricular Dysfunction (SOLVD)
22. β-Adrenergic blockade in developing heart failure: Effects on myocardial inflammatory cytokines, nitric oxide; and remodeling
23. Genetics of inflammation and risk of coronary artery disease: The central role of interleukin-6
24. Inflammation, obesity, stress and coronary heart disease: Is inteleukin-6 the link?