-
1
-
-
0036934486
-
Predicting 5-FU sensitivity using human colorectal cancer specimens: comparison of tumor dihydropyrimidine dehydrogenase and orotate phosphoribosyl transferase activities with in vitro chemosensitivity to 5-FU
-
Isshi K., Sakuyama T., Gen T., Nakamura Y., Kuroda T., Katuyama T., et al. Predicting 5-FU sensitivity using human colorectal cancer specimens: comparison of tumor dihydropyrimidine dehydrogenase and orotate phosphoribosyl transferase activities with in vitro chemosensitivity to 5-FU. Int J Clin Oncol 7 6 (2002) 335-342
-
(2002)
Int J Clin Oncol
, vol.7
, Issue.6
, pp. 335-342
-
-
Isshi, K.1
Sakuyama, T.2
Gen, T.3
Nakamura, Y.4
Kuroda, T.5
Katuyama, T.6
-
2
-
-
0842304365
-
Prognostic significance of orotate phosphoribosyl transferase activity in bladder carcinoma
-
Mizutani Y., Wada H., Fukushima M., Yoshida O., Nakanishi H., Li Y.N., et al. Prognostic significance of orotate phosphoribosyl transferase activity in bladder carcinoma. Cancer 100 4 (2004) 723-731
-
(2004)
Cancer
, vol.100
, Issue.4
, pp. 723-731
-
-
Mizutani, Y.1
Wada, H.2
Fukushima, M.3
Yoshida, O.4
Nakanishi, H.5
Li, Y.N.6
-
3
-
-
0028097137
-
A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil
-
Beck A., Etienne M.C., Cheradame S., Fischel J.L., Formento P., Renee N., et al. A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil. Eur J Cancer 30A 10 (1994) 1517-1522
-
(1994)
Eur J Cancer
, vol.30 A
, Issue.10
, pp. 1517-1522
-
-
Beck, A.1
Etienne, M.C.2
Cheradame, S.3
Fischel, J.L.4
Formento, P.5
Renee, N.6
-
4
-
-
0034012706
-
Dihydropyrimidine dehydrogenase and messenger RNA levels in gastric cancer: possible predictor for sensitivity to 5-fluorouracil
-
Ishikawa Y., Kubota T., Otani Y., Watanabe M., Teramoto T., Kumai K., et al. Dihydropyrimidine dehydrogenase and messenger RNA levels in gastric cancer: possible predictor for sensitivity to 5-fluorouracil. Jpn J Cancer Res 91 (2000) 105-112
-
(2000)
Jpn J Cancer Res
, vol.91
, pp. 105-112
-
-
Ishikawa, Y.1
Kubota, T.2
Otani, Y.3
Watanabe, M.4
Teramoto, T.5
Kumai, K.6
-
5
-
-
0036886401
-
Thymidylate synthase and dihydropyrimidine dehydrogenase expression in oral squamous cell carcinoma: an immunohistochemical and clinicopathologic study
-
Kawasaki G., Yoshitomi I., Yanamoto S., and Mizuno A. Thymidylate synthase and dihydropyrimidine dehydrogenase expression in oral squamous cell carcinoma: an immunohistochemical and clinicopathologic study. Oral Surg Oral Med Oral Pathol 94 6 (2002) 717-723
-
(2002)
Oral Surg Oral Med Oral Pathol
, vol.94
, Issue.6
, pp. 717-723
-
-
Kawasaki, G.1
Yoshitomi, I.2
Yanamoto, S.3
Mizuno, A.4
-
6
-
-
0037660429
-
Relationships between the expression of thymidylate synthase, dihydropyrimidine dehydrogenase, and orotate phosphoribosyl transferase and cell proliferative activity and 5-fluorouracil sensitivity in colorectal carcinoma
-
Fujii R., Seshimo A., and Kameoka S. Relationships between the expression of thymidylate synthase, dihydropyrimidine dehydrogenase, and orotate phosphoribosyl transferase and cell proliferative activity and 5-fluorouracil sensitivity in colorectal carcinoma. Int J Clin Oncol 8 2 (2003) 72-78
-
(2003)
Int J Clin Oncol
, vol.8
, Issue.2
, pp. 72-78
-
-
Fujii, R.1
Seshimo, A.2
Kameoka, S.3
-
7
-
-
0034241720
-
Analysis of the salvage synthesis within biosynthesis of nucleic acid route in colon cancer
-
Katsumata K., Sumi T., Murohashi T., Nagashima K., Uda O., Ashizawa T., et al. Analysis of the salvage synthesis within biosynthesis of nucleic acid route in colon cancer. Jpn J Cancer Chemother 27 9 (2000) 1415-1420
-
(2000)
Jpn J Cancer Chemother
, vol.27
, Issue.9
, pp. 1415-1420
-
-
Katsumata, K.1
Sumi, T.2
Murohashi, T.3
Nagashima, K.4
Uda, O.5
Ashizawa, T.6
-
8
-
-
0035292622
-
Expression and pathophysiologic features of orotate phosphoribosyl transferase activity (OPRT) in gastric carcinoma
-
Ochiai T., Sugitani M., Nishimura K., Noguchi H., Watanabe T., Sengoku H., et al. Expression and pathophysiologic features of orotate phosphoribosyl transferase activity (OPRT) in gastric carcinoma. Jpn J Cancer Chemother 28 3 (2001) 345-350
-
(2001)
Jpn J Cancer Chemother
, vol.28
, Issue.3
, pp. 345-350
-
-
Ochiai, T.1
Sugitani, M.2
Nishimura, K.3
Noguchi, H.4
Watanabe, T.5
Sengoku, H.6
-
9
-
-
0035348617
-
Correlation between 5-fluorouracil (5-FU) sensitivity as measured by collagen gel droplet embedded culture drug sensitivity test (CD-DST) and expression of orotate phosphoribosyl transferase (OPRT), thymidylate synthase (TS), and dihydropyrimidine dehydrogenase (DPD) in colorectal cancer
-
Ochiai T., Sugitani M., Nishimura K., Noguchi H., Watanabe T., Sengoku H., et al. Correlation between 5-fluorouracil (5-FU) sensitivity as measured by collagen gel droplet embedded culture drug sensitivity test (CD-DST) and expression of orotate phosphoribosyl transferase (OPRT), thymidylate synthase (TS), and dihydropyrimidine dehydrogenase (DPD) in colorectal cancer. Jpn J Cancer Chemother 28 5 (2001) 661-667
-
(2001)
Jpn J Cancer Chemother
, vol.28
, Issue.5
, pp. 661-667
-
-
Ochiai, T.1
Sugitani, M.2
Nishimura, K.3
Noguchi, H.4
Watanabe, T.5
Sengoku, H.6
-
10
-
-
0036516114
-
Correlation between clinical pathophysiologic factors and expression of orotate phosphoribosyl transferase (OPRT), thymidylate synthase (TS), and dihydropyrimidine dehydrogenase (DPD) in colorectal cancer
-
Ochiai T., Sugitani M., Nishimura K., Noguchi H., Watanabe T., Sengoku H., et al. Correlation between clinical pathophysiologic factors and expression of orotate phosphoribosyl transferase (OPRT), thymidylate synthase (TS), and dihydropyrimidine dehydrogenase (DPD) in colorectal cancer. Jpn J Cancer Chemother 29 3 (2002) 413-420
-
(2002)
Jpn J Cancer Chemother
, vol.29
, Issue.3
, pp. 413-420
-
-
Ochiai, T.1
Sugitani, M.2
Nishimura, K.3
Noguchi, H.4
Watanabe, T.5
Sengoku, H.6
-
11
-
-
0036884909
-
Correlation between enzymatic activity and gene expression of orotate phosphoribosyl transferase (OPRT) in colorectal cancer
-
Ochiai T., Sugitani M., Nishimura K., Noguchi H., Okada T., Suda S., et al. Correlation between enzymatic activity and gene expression of orotate phosphoribosyl transferase (OPRT) in colorectal cancer. Jpn J Cancer Chemother 29 13 (2002) 2515-2519
-
(2002)
Jpn J Cancer Chemother
, vol.29
, Issue.13
, pp. 2515-2519
-
-
Ochiai, T.1
Sugitani, M.2
Nishimura, K.3
Noguchi, H.4
Okada, T.5
Suda, S.6
-
12
-
-
3242720475
-
Choice of chemotherapeutic drugs for colorectal cancers by DPD and OPRT activities in cancer tissues
-
Takemura M., Osugi H., Lee S., Kaneko M., Tanaka Y., Fujiwara Y., et al. Choice of chemotherapeutic drugs for colorectal cancers by DPD and OPRT activities in cancer tissues. Jpn J Cancer Chemother 31 7 (2004) 1053-1056
-
(2004)
Jpn J Cancer Chemother
, vol.31
, Issue.7
, pp. 1053-1056
-
-
Takemura, M.1
Osugi, H.2
Lee, S.3
Kaneko, M.4
Tanaka, Y.5
Fujiwara, Y.6
-
13
-
-
23744479830
-
The role of thymidylate synthase and dihydropyrimidine dehydrogenase in resistance to 5-fluorouracil in human lung cancer cells
-
Oguri T., Achiwa H., Bessho Y., Muramatsu H., Maeda H., Niimi T., et al. The role of thymidylate synthase and dihydropyrimidine dehydrogenase in resistance to 5-fluorouracil in human lung cancer cells. Lung Cancer 49 3 (2005) 345-351
-
(2005)
Lung Cancer
, vol.49
, Issue.3
, pp. 345-351
-
-
Oguri, T.1
Achiwa, H.2
Bessho, Y.3
Muramatsu, H.4
Maeda, H.5
Niimi, T.6
-
14
-
-
0029922396
-
Reduced activity of anabolizing enzymes in 5-fluorouracil-resistant human stomach cancer cells
-
Inaba M., Mitsuhashi J., Sawada H., Miike N., Naoe Y., Daimon A., et al. Reduced activity of anabolizing enzymes in 5-fluorouracil-resistant human stomach cancer cells. Jpn J Cancer Res 87 (1996) 212-220
-
(1996)
Jpn J Cancer Res
, vol.87
, pp. 212-220
-
-
Inaba, M.1
Mitsuhashi, J.2
Sawada, H.3
Miike, N.4
Naoe, Y.5
Daimon, A.6
-
15
-
-
0032189399
-
Immunohistochemical evaluation of thymidylate synthase in gastric carcinoma using a new polyclonal antibody: the clinical role of thymidylate synthase as a prognostic indicator and its therapeutic usefulness
-
Kuniyasu T., Nakamura T., Tabuchi Y., and Kuroda Y. Immunohistochemical evaluation of thymidylate synthase in gastric carcinoma using a new polyclonal antibody: the clinical role of thymidylate synthase as a prognostic indicator and its therapeutic usefulness. Cancer 83 7 (1998) 1300-1306
-
(1998)
Cancer
, vol.83
, Issue.7
, pp. 1300-1306
-
-
Kuniyasu, T.1
Nakamura, T.2
Tabuchi, Y.3
Kuroda, Y.4
-
16
-
-
0034048729
-
Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase
-
Salonga D., Danenberg K.D., Johnson M., Metzger R., Groshen S., Tsao-Wei D.D., et al. Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase. Clin Cancer Res 6 4 (2000) 1322-1327
-
(2000)
Clin Cancer Res
, vol.6
, Issue.4
, pp. 1322-1327
-
-
Salonga, D.1
Danenberg, K.D.2
Johnson, M.3
Metzger, R.4
Groshen, S.5
Tsao-Wei, D.D.6
-
17
-
-
0242658929
-
Both gene expression for orotate phosphoribosyl transferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancer
-
Ichikawa W., Uetake H., Shirota Y., Yamada H., Takahashi T., Nihei Z., et al. Both gene expression for orotate phosphoribosyl transferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancer. Br J Cancer 89 8 (2003) 1486-1492
-
(2003)
Br J Cancer
, vol.89
, Issue.8
, pp. 1486-1492
-
-
Ichikawa, W.1
Uetake, H.2
Shirota, Y.3
Yamada, H.4
Takahashi, T.5
Nihei, Z.6
-
18
-
-
0027227591
-
Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats
-
Shirasaka T., Shimamoto Y., and Fukushima M. Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats. Cancer Res 53 17 (1993) 4004-4009
-
(1993)
Cancer Res
, vol.53
, Issue.17
, pp. 4004-4009
-
-
Shirasaka, T.1
Shimamoto, Y.2
Fukushima, M.3
-
19
-
-
0032080867
-
Adenovirus-mediated transduction of Escherichia coli uracil phosphoribosyltransferase gene sensitizes cancer cells to low concentrations of 5-fluorouracil
-
Kanai F., Kawakami T., Hamada H., Sadata A., Yoshida Y., Tanaka T., et al. Adenovirus-mediated transduction of Escherichia coli uracil phosphoribosyltransferase gene sensitizes cancer cells to low concentrations of 5-fluorouracil. Cancer Res 58 9 (1998) 1946-1951
-
(1998)
Cancer Res
, vol.58
, Issue.9
, pp. 1946-1951
-
-
Kanai, F.1
Kawakami, T.2
Hamada, H.3
Sadata, A.4
Yoshida, Y.5
Tanaka, T.6
-
20
-
-
7244250030
-
Influence on 5-fluorouracil metabolism by combination of interferon-alpha and 5-fluorouracil against human hepatocellular carcinoma xenografts
-
Jin C.D., Yamamoto T., Nakamura M., Arai I., Kishin R., Xing X., et al. Influence on 5-fluorouracil metabolism by combination of interferon-alpha and 5-fluorouracil against human hepatocellular carcinoma xenografts. Jpn J Cancer Chemother 31 10 (2004) 1511-1515
-
(2004)
Jpn J Cancer Chemother
, vol.31
, Issue.10
, pp. 1511-1515
-
-
Jin, C.D.1
Yamamoto, T.2
Nakamura, M.3
Arai, I.4
Kishin, R.5
Xing, X.6
-
21
-
-
2442544672
-
Orotate phosphoribosyl transferase and orotidine 5′-monophosphate decarboxylase exist as multienzyme complex in human malaria parasite Plasmodium falciparum
-
Krungkrai S.R., Prapunwattana P., Horii T., and Krungkrai J. Orotate phosphoribosyl transferase and orotidine 5′-monophosphate decarboxylase exist as multienzyme complex in human malaria parasite Plasmodium falciparum. Biochem Biophys Res Commun 318 4 (2004) 1012-1018
-
(2004)
Biochem Biophys Res Commun
, vol.318
, Issue.4
, pp. 1012-1018
-
-
Krungkrai, S.R.1
Prapunwattana, P.2
Horii, T.3
Krungkrai, J.4
-
22
-
-
0037403254
-
Chromosomal imbalances associated with acquired resistance to fluoropyrimidines in human colorectal cancer cells
-
Hidaka S., Yasutake T., Fukushima M., Yano H., Haseba M., Tsuji T., et al. Chromosomal imbalances associated with acquired resistance to fluoropyrimidines in human colorectal cancer cells. Eur J Cancer 39 7 (2003) 975-980
-
(2003)
Eur J Cancer
, vol.39
, Issue.7
, pp. 975-980
-
-
Hidaka, S.1
Yasutake, T.2
Fukushima, M.3
Yano, H.4
Haseba, M.5
Tsuji, T.6
-
23
-
-
4344564478
-
Identification of novel genes associated with the response to 5-FU treatment in gastric cancer cell lines using a cDNA microarray
-
Park J.S., Young Yoon S., Kim J.M., Yeom Y.I., Kim Y.S., and Kim N.S. Identification of novel genes associated with the response to 5-FU treatment in gastric cancer cell lines using a cDNA microarray. Cancer Lett 214 1 (2004) 19-33
-
(2004)
Cancer Lett
, vol.214
, Issue.1
, pp. 19-33
-
-
Park, J.S.1
Young Yoon, S.2
Kim, J.M.3
Yeom, Y.I.4
Kim, Y.S.5
Kim, N.S.6
-
24
-
-
4644327651
-
Orotate phosphoribosyl transferase in bladder cancer
-
Furuse H., Hirano Y., Harada M., Mugiya S., Ushiyama T., Suzuki K., et al. Orotate phosphoribosyl transferase in bladder cancer. Jpn J Cancer Chemother 31 6 (2004) 1431-1433
-
(2004)
Jpn J Cancer Chemother
, vol.31
, Issue.6
, pp. 1431-1433
-
-
Furuse, H.1
Hirano, Y.2
Harada, M.3
Mugiya, S.4
Ushiyama, T.5
Suzuki, K.6
-
25
-
-
31044445865
-
Expression of thymidylate synthase, dihydropyrimidine dehydrogenase, thymidine phosphorylase, and orotate phosphoribosyl transferase in prostate cancer
-
Miyoshi Y., Uemura H., Ishiguro H., Kitamura H., Nomura N., Danenberg P.V., et al. Expression of thymidylate synthase, dihydropyrimidine dehydrogenase, thymidine phosphorylase, and orotate phosphoribosyl transferase in prostate cancer. Prostate Cancer Prostatic Dis 8 3 (2005) 260-265
-
(2005)
Prostate Cancer Prostatic Dis
, vol.8
, Issue.3
, pp. 260-265
-
-
Miyoshi, Y.1
Uemura, H.2
Ishiguro, H.3
Kitamura, H.4
Nomura, N.5
Danenberg, P.V.6
-
26
-
-
0019413343
-
Metabolism of pyrimidine nucleotides in various tissues and tumor cells from rodents
-
Ikenaka K., Fukushima M., Nakamura H., Okamoto M., Shirasaka T., and Fujii S. Metabolism of pyrimidine nucleotides in various tissues and tumor cells from rodents. Gann 72 (1981) 590-597
-
(1981)
Gann
, vol.72
, pp. 590-597
-
-
Ikenaka, K.1
Fukushima, M.2
Nakamura, H.3
Okamoto, M.4
Shirasaka, T.5
Fujii, S.6
-
27
-
-
0025351196
-
Comparison of pyrimidine nucleotide synthetic enzymes involved in 5-fluorouracil metabolism between human adenocarcinomas and squamous cell carcinomas
-
Maehara Y., Moriguchi S., Emi Y., Watanabe A., Kohnoe S., Tsujitani S., et al. Comparison of pyrimidine nucleotide synthetic enzymes involved in 5-fluorouracil metabolism between human adenocarcinomas and squamous cell carcinomas. Cancer 66 1 (1990) 156-161
-
(1990)
Cancer
, vol.66
, Issue.1
, pp. 156-161
-
-
Maehara, Y.1
Moriguchi, S.2
Emi, Y.3
Watanabe, A.4
Kohnoe, S.5
Tsujitani, S.6
-
28
-
-
0026045814
-
A comparison of 5-fluorouracil metabolism in human colorectal cancer and colon mucosa
-
Peters G.J., van Groeningen C.J., Laurensse E.J., and Pinedo H.M. A comparison of 5-fluorouracil metabolism in human colorectal cancer and colon mucosa. Cancer 68 9 (1991) 1903-1909
-
(1991)
Cancer
, vol.68
, Issue.9
, pp. 1903-1909
-
-
Peters, G.J.1
van Groeningen, C.J.2
Laurensse, E.J.3
Pinedo, H.M.4
|