A new strategy for in vivo spectral editing. Application to GABA editing using selective homonuclear polarization transfer spectroscopy

Journal of Magnetic Resonance

Volumn 170, Issue 2, 2004, Pages 290-298

  Shen, Jun ^a   Yang, Jehoon ^a   Choi, In Young ^b   Steve Li, Shizhe ^a   Chen, Zhengguang ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

Author keywords

GABA; Polarization transfer; Quantification; Spectral editing; Vigabatrin

Indexed keywords

COMPUTER SIMULATION; FREQUENCIES; MAGNETIC FIELDS; MAGNETIZATION; PHASE SHIFT; POLARIZATION; QUANTUM THEORY; SIGNAL SYSTEMS; SPECTROSCOPY;

GABA; POLARIZATION TRANSFER; QUANTIFICATION; SPECTRAL EDITING; VIGABATRIN;

MAGNETIC RESONANCE;

4 AMINOBUTYRIC ACID;

ANIMAL; ARTICLE; BRAIN LEVEL; CHEMISTRY; COMPUTER SIMULATION; MALE; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; BRAIN CHEMISTRY; COMPUTER SIMULATION; GAMMA-AMINOBUTYRIC ACID; MAGNETIC RESONANCE SPECTROSCOPY; MALE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 4544347718     PISSN: 10907807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmr.2004.05.022     Document Type: Article

References (36)

1. 1H NMR spectra of human brain, Magn. Reson. Med, 32 (1994) 294-302.
2. 13C]glucose is reduced in rats treated with GABA-transaminase inhibitor vigabatrin (γ-vinyl GABA), Neurochem. Res. 21 (1996) 1031-1041.
3. 1H NMR measurements of γ-aminobutyric acid in human brain in vivo, Proc. Natl. Acad. Sci. USA 90 (1993) 5662-5666.
4. H.P. Hetherington, B.R. Newcomer, J.W. Pan, Measurements of human cerebral GABA at 4.1T using numerically optimized editing pulses, Magn. Reson. Med. 39 (1998) 6-10.
5. M. Mescher, H. Merkle, J. Kirsch, M. Garwood, R. Gruetter, Simultaneous in vivo spectral editing and water suppression, NMR Biomed. 11 (1998) 266-272.
6. J.R. Keltner, L.L. Wald, J.D. Christensen, L.C. Maas, C.M. Moore, B.M. Cohen, P.F. Renshaw, A technique for detecting GABA in the human brain with PRESS localization and optimized refocusing spectral editing radiofrequency pulses, Magn. Reson. Med. 36 (1996) 458-461.
7. P.G. Henry, C. Dautry, P. Hantraye, G. Bloch, Brain GABA editing without macromolecule contamination, Magn, Reson. Med. 45 (2001) 517-520.
8. M. Terpstra, K. Ugurbil, R. Gruetter, Direct in vivo measurement of human cerebral GABA concentration using MEGA-editing at 7T, Magn. Reson. Med. 47 (2002) 1009-1012.
9. R.A. de Graaf, D.L. Rothman, Detection of gamma-aminobutyric acid (GABA) by longitudinal scalar order difference editing, J. Magn. Reson. 152 (2001) 124-131.
10. J.R. Keltner, L.L. Wald, B.D. Frederick, P.F. Renshaw, In vivo detection of GABA in human brain using a localized double-quantum filter technique, Magn. Reson. Med. 37 (1997) 366-371.
11. J. Shen, D.C. Shungu, D.L. Rothman, In vivo chemical shift imaging of γ-aminobutyric acid in the human brain, Magn. Reson. Med. 41 (1999) 35-42.
12. J. Shen, D.L. Rothman, P. Brown, In vivo GABA editing using a novel doubly selective multiple quantum filter, Magn. Reson. Med. 47 (2002) 447-454.
13. J. Shen, Slice-selective J-coupled coherence transfer using symmetric linear phase pulses: applications to localized GABA spectroscopy, J. Magn. Reson. 163 (2003) 73-80.
14. I.-Y. Choi, S.-P. Lee, H. Merkle, J. Shen, A single-shot two-echo method for simultaneous detection of multiple quantum filtered GABA and single quantum Cr in the human brain in vivo, Magn. Reson. Med. 51 (2004) 1121-1151.
15. F. Du, W.J. Chu, B. Yang, J.A. Den Hollander, T.C. Ng, In vivo GABA detection with improved selectivity and sensitivity by localized double quantum filter technique at 4.1 T, Magn. Reson. Imag. 22 (2004) 103-108.
16. Z.J. Wang, C. Bergqvist, J.V. Hunter, D. Jin, D.J. Wang, S. Wehrli, R.A. Zimmerman, In vivo measurement of brain metabolites using two-dimensional double-quantum MR spectroscopy-exploration of GABA levels in a ketogenic diet, Magn. Reson. Med. 49 (2003) 615-619.
17. Y. Ke, B.M. Cohen, J.Y. Bang, M. Yang, P.P. Renshaw, Assessment of Gaba concentration in human brain using two-dimensional proton magnetic resonance spectroscopy, Psychiatric Res. 100 (2000) 167-178.
18. J.W. Welch, K. Bhakoo, R.M. Dixon, P. Styles, N.R. Sibson, A.M. Blaimire, In vivo monitoring of rat brain metabolites during vigabatrin treatment using localized 2D-COSY, NMR Biomed. 16 (2003) 47-54.
19. J. Urenjak, S.R. Williams, D.G. Gadian, M. Noble, Specific expression of N-acetylaspartate in neurons, oligodendrocyte-type-2 astrocyte progenitors, and immature oligodendrocytes in vitro, J. Neurochem. 59 (1992) 55-61.
20. M.J. Jung, B. Lippert, B.W. Metcalf, P. Bohlen, P.J. Schechter, Gamma-vinyl GABA (4-amino-hex-5-enoic acid), a new selective irreversible inhibitor of GABA-T: effects on brain GABA metabolism in mice, J. Neurochem. 29 (1977) 797-802.
21. J. Shen, I.-Y. Choi, J. Yang, S.S. Li, Z. Chen, A novel strategy for editing neurotransmitter GABA in brain using ID polarization transfer, The 45th Experimental Nuclear Magnetic Resonance Conference, Abstract #223, Pacific Grove, CA, 2004.
22. J. Shen, D.L. Rothman, H.P. Hetherington, J.W. Pan, Linear projection method for automatic slice shimming, Magn. Reson. Med. 42 (1999) 1082-1088.
23. 0 inhomogeneity in the rat brain at 11.7 T, Magn. Reson. Imag. 22 (2004) 835-842.
24. M.L. Tappaz, M.J. Brownstein, I.K. Kopin, Glutamate decarboxylase (GAD) and gamma-aminobutyric acid (GABA) in discrete nuclei of hypothalamus and substantia nigra, Brain Res. 125 (1977) 109-121.
25. D. Dimitrijevic, P.S. Whitton, M. Domin, K. Welham, A.T. Florence, Increased vigabatrin entry into the brain by polysorbate 80 and sodium caprate, J. Pharm. Pharmacol. 53 (2001) 149-154.
26. S. Conolly, G. Glover, D. Nishimura, A. Macovski, A reduced power selective adiabatic spin-echo pulse sequence, Magn. Reson. Med. 18 (1991) 28-38.
27. 1H NMR spectra of the rat brain, 141 (1999) 104-120.
28. K. Ishikawa, S. Watebe, N. Goto, Laminar distribution of γaminobutyric acid (GABA) in the occipital cortex of rats: evidence as a neurotransmitter, Brain Res. 277 (1983) 361-364.
29. J.M. Miller, R. Jope, T.N. Ferraro, T.A. Hare, Brain amino acid concentrations in rats killed by decapitation and microwave irradiation, J. Neurosci. Methods 31 (1990) 187-192.
30. Z. Chen, A.C. Silva, J. Yang, J. Shen, Elevated endogenous GABA level correlates with decreased fMRI Signals in αchloralose anaesthetized rat brain during acute inhibition of GABA-Transaminase, J. Neurosci. Res. (submitted).
31. 2 multiplet measured pre- and post-administration of vigabatrin in human brain, Magn. Reson. Med. 48 (2002) 617-623.
32. J. Shen, E.J. Novotny, D.L. Rothman, In vivo lactate and βhydroxybutyrate editing using a pure phase refocusing pulse train, Magn. Reson. Med. 40 (1998) 783-788.
33. H. Lei, J. Peeling, Simultaneous lactate editing and observation of other metabolites using a stimulated-echo-enhanced double quantum filter, J. Magn. Reson. 137 (1999) 215-220.
34. J. Star-Lack, D. Spielman, E. Adalsteinsson, J. Kurhanewicz, D.J. Terris, D.B. Vigneron, In vivo lactate editing with simultaneous detection of choline, creatine, NAA, and lipid singlets at 1.5 T using PRESS excitation with applications to the study of brain and head and neck tumors, J. Magn. Reson. 133 (1998) 243-254.
35. Q. He, Z.M. Bhujwalla, J.D. Glickson, Proton detection of choline and lactate in EMT6 tumors by spin-echo-enhanced selective multiple-quantum-coherence transfer, J. Magn. Reson. B 112 (1996) 18-25.
36. A.H. Wilman, M. Astridge, R.E. Snyder, P.S. Allen, Same-scan acquisition of both edited J-coupled multiplets and singlet resonances of uncoupled spins for proton MRS, J. Magn. Reson. B. 109 (1995) 202-205.