GABA X2 multiplet measured pre- and post-administration of vigabatrin in human brain

Magnetic Resonance in Medicine

Volumn 48, Issue 4, 2002, Pages 617-623

  Hanstock, Christopher C ^a   Coupland, Nicholas J ^a   Allen, Peter S ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

GABA; Glutamate; Human brain; MRS; Vigabatrin

Indexed keywords

METABOLITES; SPIN DYNAMICS;

ACQUISITION MODES; GABA; GLUTAMATE; HUMAN BRAIN; SEQUENCE PARAMETERS; SPECTRAL RESPONSE; STIMULATED ECHOS; VIGABATRIN;

BRAIN;

4 AMINOBUTYRIC ACID; GLUTAMIC ACID; VIGABATRIN; DRUG DERIVATIVE;

ARTICLE; BRAIN; CALCULATION; HUMAN; IMAGE ENHANCEMENT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OCCIPITAL CORTEX; PARIETAL LOBE; PHANTOM; QUANTITATIVE ANALYSIS; DRUG EFFECT; IMAGE QUALITY; METABOLISM; METHODOLOGY;

BRAIN; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PHANTOMS, IMAGING; VIGABATRIN;

EID: 0036771648     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.10265     Document Type: Article

References (41)

1. 1H NMR measurements of γ-aminobutyric acid in human brain in vivo. Proc Natl Acad Sci USA 1993;90:5662-5666.
2. 1H spectroscopic measurements of γ-aminobutyric acid, glutamate, and glutamine in human brain. Epilepsia 1995;36:457-464.
3. Hyder F, Petroff OAC, Mattson RH, Rothman DL. Localized 1H NMR measurements of 2-pyrrolidinone in human brain in vivo. Magn Reson Med 1999;41:889-896.
4. Shen J, Shungu DC, Rothman DL. In vivo chemical shift imaging of γ-aminobutyric acid in the human brain. Magn Reson Med 1999;41:35-42.
5. De Graaf RA, Rothman DL. Detection of γ-aminobutyric acid (GABA) by longitudinal scalar order difference editing. J Magn Reson 2001;152: 124-131.
6. Keltner JR, Wald LL, Christensen JD, Maas LC, Moore CM, Cohen BM, Renshaw PF. A technique for detecting GABA in the human brain with PRESS localization and optimized refocusing spectral editing radiofrequency pulses. Magn Reson Med 1996;36,458-461.
7. Keltner JR, Wald LL, Frederick BDB, Renshaw PF. In vivo detection of GABA in human brain using a localized double-quantum filter technique. Magn Reson Med 1997;37:366-371.
8. Hetherington HP, Newcomer BR, Pan JW. Measurements of human cerebral GABA at 4.1 T using numerically optimized editing pulses. Magn Reson Med 1998;39:6-10.
9. Kuzniesky R, Hetherington H, Ho S, Pan J, Martin R, Gilliam F, Hugg J, Faught E. Topiramate increases cerebral GABA in healthy humans. Neurology 1998;51:627-630.
10. Weber OM, Verhagen A, Duc CO, Meier D, Leenders KL, Boesiger P. Effects of vigabatrin intake on brain GABA activity as monitored by spectrally edited magnetic resonance spectroscopy and positron emission tomography. Magn Reson Imaging 1999;17:417-425.
11. Ke Y, Cohen BM, Bang JY, Yang M, Renshaw PF. Assessment of GABA concentration in human brain using two-dimensional proton magnetic resonance spectroscopy. Psychiatr Res 2000;100:169-178.
12. 1H-NMR-spectroscopy: responder characteristics. Epilepsia 2001;42:29-40.
13. Terpstra M, Ugurbil K, Gruetter R. Direct in vivo measurement of cerebral GABA in humans using MEGA-editing at 7 Tesla. In: Proceedings of the 9th Annual Meeting of ISMRM, Glasgow, Scotland, 2001. p 961.
14. McLean M, Simister R, Woermann F, Wald L, Williams S, Duncan J. In vivo GABA measurement using a PRESS-localized double quantum filter in patients with malformations of cortical development and epilepsy. In: Proceedings of the 9th Annual Meeting of ISMRM, Glasgow, Scotland, 2001. p 962.
15. Watenabe H, Umeda M, Okamoto K, Oda M, Kanamatsu T, Tsukada Y, Matsumoto A, Otsuki T. GABA detection in the human brain using a 3D localized selective double quantum filter. In: Proceedings of the 9th Annual Meeting of ISMRM, Glasgow, Scotland, 2001. p 963.
16. Provencher SW. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med 1993;30:672-679.
17. 1H MR spectra: prior knowledge, peak elimination, and filtering. NMR Biomed 1999;12:205-216.
18. 1H MR spectra of brain using AMARES. NMR Biomed 1998;11:32-39.
19. Bottomly PA. Selective volume method for performing localized NMR spectroscopy. U.S. patent 4 480/228; 1984.
20. Frahm J, Merboldt KD, Hanicke W. Localized proton spectroscopy using stimulated echoes. J Magn Reson 1987;72:502-508.
21. Petroff OA, Mattson RH, Behar KL, Hyder F, Rothman DL. Vigabatrin increases human brain homocarnosine and improves seizure control. Ann Neurol 1998;44:948-952.
22. Govindaraju V, Young K, Maudsley AA. Proton NMR chemical shifts and coupling constants for brain metabolites. NMR Biomed 2000;13: 129-153.
23. 1H NMR spectra of human brain. Magn Reson Med 1994;32:294-302.
24. 1H NMR spectroscopy of the human brain at 7T. Magn Reson Med 2001;46:451-456.
25. Wilman AH, Allen PS. In vivo detection strategies for γ-aminobutyric acid, utilizing proton spectroscopy and coherence pathway filtering with gradients. J Magn Reson Ser B 1993;101:165-171.
26. Wilman AH, Allen PS. Yield enhancement of a double-quantum filter sequence designed for the edited detection of GABA. J Magn Reson Ser B 1995;109:169-174.
27. 1H NMR spectroscopy studies of extracts of human cerebral neoplasms. Magn Reson Med 1992;24: 123-136.
28. Perry TL, Hansen S, Gandham SS. Postmortem changes of amino compounds in human and rat brain. J Neurochem 1981;36:406-412.
29. Petroff OA, Spencer DD, Alger JR, Prichard JW. High-field proton magnetic resonance spectroscopy of human cerebrum obtained during surgery for epilepsy. Neurology 1989;39:1197-1202.
30. Perry TL, Hansen S, Berry K, Mok C, Lesk D. Free amino acids and related compounds in biopsies of human brain. J Neurochem 1971;18: 521-528.
31. Perry TL, Yong VW, Bergeron C, Hansen S, Jones K. Amino acids, glutathione, and glutathione transferase activity in the brains of patients with Alzheimer's disease. Ann Neurol 1987;21:331-336.
32. Lefauconnier JM, Portemer C, Chatagner F. Free amino acids and related substances in human glial tumours and in fetal brain: comparison with normal adult brain. Brain Res 1976;117:105-113.
33. Thompson RB, Allen PS. Response of metabolites with coupled spins to the STEAM sequence. Magn Reson Med 2001;45:955-965.
34. Thompson RB, Allen PS. Sources of variability in the response of coupled spins to the PRESS sequence and their potential impact on metabolite quantification. Magn Reson Med 1999;41:1162-1169.
35. Thompson RB, Allen PS. A new multiple quantum filter design procedure for use on strongly coupled spin systems found in vivo: its application to glutamate. Magn Reson Med 1998;39:762-771.
36. Gruetter R. Automatic, localized in vivo adjustment of all first- and second-order shim coils. Magn Reson Med 1993;29:804-811.
37. Sutoo D, Akiyama K, Yabe K. Quantitative maps of GABAergic and glutamatergic neuronal systems in the human brain. Hum Brain Mapp 2000;11:93-103.
38. Manton DJ, Lowry M, Blackband SJ, Horsman A. Determination of proton metabolite concentrations and relaxation parameters in normal human brain and intracranial tumours. NMR Biomed 1995;8:104-112.
39. Toft PB, Christiansen P, Pryds O, Lou HC, Henriksen O. T1, T2, and concentrations of brain metabolites in neonates and adolescents estimated with H-1 MR spectroscopy. J Magn Reson Imaging 1994;4:1-5.
40. Frahm J, Bruhn H, Gyngell ML, Merboldt KD, Hanicke W, Sauter R. Localized proton NMR spectroscopy in different regions of the human brain in vivo. Relaxation times and concentrations of cerebral metabolites. Magn Reson Med 1989;11:47-63.
41. Jeon SG, Bahn JH, Jang JS, Park J, Kwon OS, Cho SW, Choi SY. Human brain GABA transaminase tissue distribution and molecular expression. Eur J Biochem 2000;267:5601-5607.