Enhanced patient serum immunoreactivity to recombinant Mycobacterium tuberculosis CFP32 produced in the yeast Pichia pastoris compared to Escherichia coli and its potential for serodiagnosis of tuberculosis

Journal of Clinical Microbiology

Volumn 44, Issue 9, 2006, Pages 3086-3093

  Benabdesselem, Chaouki ^a   Fathallah, Dahmani M ^a   Huard, Richard C ^b,c   Zhu, Hongxia ^b   Jarboui, Mohamed Ali ^a   Dellagi, Koussay ^a   Ho, John L ^b   Barbouche, Ridha M ^a  

^a PASTEUR INSTITUTE OF TUNIS   (Tunisia)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BCG VACCINE; MYCOBACTERIUM ANTIGEN; POLYCLONAL ANTISERUM; PROTEIN CFP32; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ANTIBODY PRODUCTION; ANTIGEN RECOGNITION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; FEMALE; HUMAN; IMMUNOASSAY; IMMUNOREACTIVITY; MALE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN SYNTHESIS; SENSITIVITY AND SPECIFICITY; SERODIAGNOSIS; SPUTUM ANALYSIS; TUBERCULOSIS; WESTERN BLOTTING;

ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; ESCHERICHIA COLI; HUMANS; MYCOBACTERIUM TUBERCULOSIS; PICHIA; RECOMBINANT PROTEINS; SENSITIVITY AND SPECIFICITY; SEROLOGIC TESTS; TUBERCULOSIS, PULMONARY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MYCOBACTERIUM BOVIS; MYCOBACTERIUM BOVIS BCG; MYCOBACTERIUM TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS COMPLEX; PICHIA; PICHIA PASTORIS;

EID: 33748800753     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.02672-05     Document Type: Article

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