The human Vps29 retromer component is a metallo-phosphoesterase for a cation-independent mannose 6-phosphate receptor substrate peptide

Biochemical Journal

Volumn 398, Issue 3, 2006, Pages 399-409

  Damen, Ester ^a   Krieger, Elmar ^b   Nielsen, Jens E ^c   Eygensteyn, Jelle ^a   Van Leeuwen, Jeroen E M ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Cargo protein; Cation independent mannose 6 phosphate receptor (CI M6PR); Metallo phosphoesterase; Retromer; Trans Golgi network; Transport; Vacuolar sorting protein 29 (Vps29)

Indexed keywords

CHELATION; COMPLEXATION; CRYSTAL STRUCTURE; POSITIVE IONS; SUBSTITUTION REACTIONS; SUBSTRATES;

CARGO PROTEINS; CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR (CI-M6PR); METALLO-PHOSPHOESTERASE; RETROMERS; TRANS GOLGI NETWORK; VACUOLAR SORTING PROTEIN 29 (VPS29);

ENZYMES;

ALANINE; ASPARAGINE; ASPARTIC ACID; BINDING PROTEIN; CARRIER PROTEIN; CATION; CHELATING AGENT; LEUCINE; METAL ION; MUTANT PROTEIN; PHOSPHATASE; RECOMBINANT PROTEIN; SERINE; SOMATOMEDIN B RECEPTOR; UNCLASSIFIED DRUG; VACUOLAR SORTING PROTEIN 26; VACUOLAR SORTING PROTEIN 29; VACUOLAR SORTING PROTEIN 35; ZINC; ZINC CHLORIDE; VPS29 PROTEIN, HUMAN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; EUKARYOTE; IN VITRO STUDY; MASS SPECTROMETRY; MOLECULAR MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING; ANIMAL; BINDING SITE; CELL STRAIN 3T3; CHEMICAL STRUCTURE; ENZYME SPECIFICITY; ESCHERICHIA COLI; HUMAN; METABOLISM; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN MOTIF;

EUKARYOTA;

AMINO ACID MOTIFS; ANIMALS; BINDING SITES; CARRIER PROTEINS; CATIONS; CHELATING AGENTS; ESCHERICHIA COLI; HUMANS; MICE; MODELS, MOLECULAR; NIH 3T3 CELLS; PROTEIN CONFORMATION; PROTEIN FOLDING; RECEPTOR, IGF TYPE 2; SUBSTRATE SPECIFICITY;

EID: 33748746143     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20060033     Document Type: Article

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