Both hepatic and extrahepatic ABCA1 have discrete and essential functions in the maintenance of plasma high-density lipoprotein cholesterol levels in vivo

Circulation

Volumn 114, Issue 12, 2006, Pages 1301-1309

  Singaraja, Roshni R ^a   Van Eck, Miranda ^b   Bissada, Nagat ^a   Zimetti, Francesca ^c   Collins, Heidi L ^c   Hildebrand, Reeni B ^b   Hayden, Anna ^a   Brunham, Liam R ^a   Kang, Martin H ^a   Fruchart, Jean Charles ^d   Van Berkel, Theo J C ^b   Parks, John S ^e   Staels, Bart ^d   Rothblat, George H ^c   Fiévet, Catherine ^d   Hayden, Michael R ^a,f  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b LEIDEN UNIVERSITY   (Netherlands)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^d INSTITUT PASTEUR DE LILLE   (France)

^e WAKE FOREST SCHOOL OF MEDICINE   (United States)

^f NONE   (Canada)

Author keywords

Cholesterol; Lipids; Lipoproteins

Indexed keywords

ABC TRANSPORTER A1; ADENOVIRUS VECTOR; APOLIPOPROTEIN A1; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; PHOSPHOLIPID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOGENESIS; CHOLESTEROL BLOOD LEVEL; COMPARATIVE STUDY; CONTROLLED STUDY; GENE DELETION; GENE EXPRESSION; GENE TARGETING; IN VIVO STUDY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; WILD TYPE;

ADENOVIRIDAE; ANIMALS; APOLIPOPROTEIN A-I; ATP-BINDING CASSETTE TRANSPORTERS; CHOLESTEROL, HDL; FEMALE; GENE EXPRESSION REGULATION; HUMANS; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT;

EID: 33748743543     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.106.621433     Document Type: Article

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