The prolactin-deficient mouse has an unaltered metabolic phenotype

Endocrinology

Volumn 147, Issue 10, 2006, Pages 4638-4645

  LaPensee, Christopher R ^a   Horseman, Nelson D ^a   Tso, Patrick ^a   Brandebourg, Terry D ^a   Hugo, Eric R ^a   Ben Jonathan, Nira ^a,b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; CHOLESTEROL; FATTY ACID; LEPTIN; PHOSPHOLIPID; PROLACTIN; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ARTICLE; BODY COMPOSITION; CONTROLLED STUDY; EXPERIMENTAL MODEL; EXPLANT; GLUCOSE TOLERANCE; HOMEOSTASIS; HORMONE ACTION; HORMONE DEFICIENCY; LIPID BLOOD LEVEL; LIPOLYSIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SEX DIFFERENCE; WEIGHT GAIN;

ADIPONECTIN; ADIPOSE TISSUE; ANIMALS; BODY COMPOSITION; DIET, FAT-RESTRICTED; DIETARY FATS; FEMALE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HUMANS; LEPTIN; LIPIDS; LIPOLYSIS; LYMPHOCYTES; MALE; METABOLISM; MICE; MICE, KNOCKOUT; PHENOTYPE; PROLACTIN; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEX CHARACTERISTICS; WEIGHT GAIN;

EID: 33748743093     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2006-0487     Document Type: Article

References (53)

1. Meier AH 1969 Diurnal variations of metabolic responses to prolactin in lower vertebrates. Gen Comp Endocrinol 12:55-62
2. Buntin JD, Hnasko RM, Zuzick PH 1999 Role of the ventromedial hypothalamus in prolactin-induced hyperphagia in ring doves. Physiol Behav 66:255-261
3. Ben Jonathan N, Hugo ER, Brandebourg TD, Lapensee CR 2006 Focus on prolactin as a metabolic hormone. Trends Endocrinol Metab 117:110-116
4. Neville MC, McFadden TB, Forsyth I 2002 Hormonal regulation of mammary differentiation and milk secretion. J Mammary Gland Biol Neoplasia 7:49-66
5. Sorenson RL, Brelje TC 1997 Adaptation of islets of Langerhans to pregnancy: β-cell growth, enhanced insulin secretion and the role of lactogenic hormones. Horm Metab Res 29:301-307
6. Sorenson RL, Brelje TC, Hegre OD, Marshall S, Anaya P, Sheridan JD 1987 Prolactin (in vitro) decreases the glucose stimulation threshold, enhances insulin secretion, and increases dye coupling among islet B cells. Endocrinology 121:1447-1453
7. Costello LC, Franklin RB 2002 Testosterone and prolactin regulation of metabolic genes and citrate metabolism of prostate epithelial cells. Horm Metab Res 34:417-424
8. Hugo ER, Brandebourg TD, Comstock CE, Gersin KS, Sussman JJ, Ben Jonathan N 2006 LS14: a novel human adipocyte cell line that produces prolactin. Endocrinology 147:306-313
9. Ling C, Hellgren G, Gebre-Medhin M, Dillner K, Wennbo H, Carlsson B, Billig H 2000 Prolactin (PRL) receptor gene expression in mouse adipose tissue: increases during lactation and in PRL-transgenic mice. Endocrinology 141:3564-3572
10. Ling C, Svensson L, Oden B, Weijdegard B, Eden B, Eden S, Billig H 2003 Identification of functional prolactin (PRL) receptor gene expression: PRL inhibits lipoprotein lipase activity in human white adipose tissue. J Clin Endocrinol Metab 88:1804-1808
11. Royster M, Driscoll P, Kelly PA, Freemark M 1995 The prolactin receptor in the fetal rat: cellular localization of messenger ribonucleic acid, immunoreactive protein, and ligand-binding activity and induction of expression in late gestation. Endocrinology 136:3892-3900
12. Symonds ME, Phillips ID, Anthony RV, Owens JA, McMillen IC 1998 Prolactin receptor gene expression and fetal adipose tissue. J Neuroendocrinol 10:885-890
13. Flint DJ, Binart N, Kopchick J, Kelly P 2003 Effects of growth hormone and prolactin on adipose tissue development and function. Pituitary 6:97-102
14. Hogan JC, Stephens JM 2005 The regulation of fatty acid synthase by STAT5A. Diabetes 54:1968-1975
15. Fielder PJ, Talamantes F 1987 The lipolytic effects of mouse placental lactogen II, mouse prolactin, and mouse growth hormone on adipose tissue from virgin and pregnant mice. Endocrinology 121:493-497
16. Houseknecht KL, Bauman DE, Vernon RG, Byatt JC, Collier RJ 1996 Insulin-like growth factors-I and -II, somatotropin, prolactin, and placental lactogen are not acute effectors of lipolysis in ruminants. Domest Anim Endocrinol 13:239-249
17. Fortun-Lamothe L, Langin D, Lafontan M 1996 Influence of prolactin on in vivo and in vitro lipolysis in rabbits. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 115:141-147
18. Ahima RS, Saper CB, Flier JS, Elmquist JK 2000 Leptin regulation of neuroendocrine systems. Front Neuroendocrinol 21:263-307
19. Ahima RS, Flier JS 2000 Adipose tissue as an endocrine organ. Trends Endocrinol Metab 11:327-332
20. Combs TP, Berg AH, Rajala MW, Klebanov S, Iyengar P, Jimenez-Chillaron JC, Patti ME, Klein SL, Weinstein RS, Scherer PE 2003 Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte-specific secretory protein adiponectin. Diabetes 52:268-276
21. Nilsson L, Binart N, Bohlooly Y, Bramnert M, Egecioglu E, Kindblom J, Kelly PA, Kopchick JJ, Ormandy CJ, Ling C, Billig H 2005 Prolactin and growth hormone regulate adiponectin secretion and receptor expression in adipose tissue. Biochem Biophys Res Commun 331:1120-1126
22. Freemark M, Fleenor D, Driscoll P, Binart N, Kelly P 2001 Body weight and fat deposition in prolactin receptor-deficient mice. Endocrinology 142:532-537
23. Gualillo O, Lago F, Garcia M, Menendez C, Senaris R, Casanueva FF, Dieguez C 1999 Prolactin stimulates leptin secretion by rat white adipose tissue. Endocrinology 140:5149-5153
24. Ling C, Billig H 2001 PRL receptor-mediated effects in female mouse adipocytes: PRL induces suppressors of cytokine signaling expression and suppresses insulin-induced leptin production in adipocytes in vitro. Endocrinology 142:4880-4890
25. Viengchareun S, Bouzinba-Segard H, Laigneau JP, Zennaro MC, Kelly PA, Bado A, Lombes M, Binart N 2004 Prolactin potentiates insulin-stimulated leptin expression and release from differentiated brown adipocytes. J Mol Endocrinol 33:679-691
26. Baptista T, de Baptista EA, Lalonde J, Plamondon J, Kin NM, Beaulieu S, Joober R, Richard D 2004 Comparative effects of the antipsychotics sulpiride and risperidone in female rats on energy balance, body composition, fat morphology and macronutrient selection. Prog Neuropsychopharmacol Biol Psychiatry 28:1305-1311
27. Byatt JC, Staten NR, Salsgiver WJ, Kostelc JG, Collier RJ 1993 Stimulation of food intake and weight gain in mature female rats by bovine prolactin and bovine growth hormone. Am J Physiol 264:E986-E992
28. Gerardo-Gettens T, Moore BJ, Stern JS, Horwitz BA 1989 Prolactin stimulates food intake in a dose-dependent manner. Am J Physiol 256:R276-R280
29. Sauve D, Woodside B 2000 Neuroanatomical specificity of prolactin-induced hyperphagia in virgin female rats. Brain Res 868:306-314
30. Doknic M, Pekic S, Zarkovic M, Medic-Stojanoska M, Dieguez C, Casanueva F, Popovic V 2002 Dopaminergic tone and obesity: an insight from prolactinomas treated with bromocriptine. Eur J Endocrinol 147:77-84
31. Greenman Y, Tordjman K, Stern N 1998 Increased body weight associated with prolactin secreting pituitary adenomas: weight loss with normalization of prolactin levels. Clin Endocrinol (Oxf) 48:547-553
32. Fleenor D, Oden J, Kelly PA, Mohan S, Alliouachene S, Pende M, Wentz S, Kerr J, Freemark M 2005 Roles of the lactogens and somatogens in perinatal and postnatal metabolism and growth: studies of a novel mouse model combining lactogen resistance and growth hormone deficiency. Endocrinology 146:103-112
33. Matsuda M, Mori T, Sassa S, Sakamoto S, Park MK, Kawashima S 1996 Chronic effect of hyperprolactinemia on blood glucose and lipid levels in mice. Life Sci 58:1171-1177
34. Horseman ND, Zhao W, Montecino-Rodriguez E, Tanaka M, Nakashima K, Engle SJ, Smith F, Markoff E, Dorshkind K 1997 Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene. EMBO J 16:6926-6935
35. Zinger M, McFarland M, Ben-Jonathan N 2003 Prolactin expression and secretion by human breast glandular and adipose tissue. J Clin Endocrinol Metab 88:689-696
36. Pfaffl MW, Horgan GW, Dempfle L 2002 Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 30:e36
37. Takayama M, Itoh S, Nagasaki T, Tanimizu I 1977 A new enzymatic method for determination of serum choline-containing phospholipids. Clin Chim Acta 79:93-98
38. Cruz-Soto ME, Scheiber MD, Gregerson KA, Boivin GP, Horseman ND 2002 Pituitary tumorigenesis in prolactin gene-disrupted mice. Endocrinology 143:4429-4436
39. Schuff KG, Hentges ST, Kelly MA, Binart N, Kelly PA, Iuvone PM, Asa SL, Low MJ 2002 Lack of prolactin receptor signaling in mice results in lactotroph proliferation and prolactinomas by dopamine-dependent and -independent mechanisms. J Clin Invest 110:973-981
40. Freemark M, Avril I, Fleenor D, Driscoll P, Petro A, Opara E, Kendall W, Oden J, Bridges S, Binart N, Breant B, Kelly PA 2002 Targeted deletion of the PRL receptor: effects on islet development, insulin production, and glucose tolerance. Endocrinology 143:1378-1385
41. Cincotta AH, Tozzo E, Scislowski PW 1997 Bromocriptine/SKF38393 treatment ameliorates obesity and associated metabolic dysfunctions in obese (ob/ob) mice. Life Sci 61:951-956
42. Moore BJ, Gerardo-Gettens T, Horwitz BA, Stern JS 1986 Hyperprolactinemia stimulates food intake in the female rat. Brain Res Bull 17:563-569
43. Noel MB, Woodside B 1993 Effects of systemic and central prolactin injections on food intake, weight gain, and estrous cyclicity in female rats. Physiol Behav 54:151-154
44. Kopelman PG 2000 Physiopathology of prolactin secretion in obesity. Int J Obes Relat Metab Disord 24(Suppl 2):S104-S108
45. Baptista T, Lacruz A, Meza T, Contreras Q, Delgado C, Mejias MA, Hernandez L 2001 Antipsychotic drugs and obesity: is prolactin involved? Can J Psychiatry 46:829-834
46. Ros M, Lobato MF, Garcia-Ruiz JP, Moreno FJ 1990 Integration of lipid metabolism in the mammary gland and adipose tissue by prolactin during lactation. Mol Cell Biochem 93:185-194
47. Mystkowski P, Schwartz MW 2000 Gonadal steroids and energy homeostasis in the leptin era. Nutrition 16:937-946
48. Berg AH, Combs TP, Scherer PE 2002 ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metab 13:84-89
49. Brelje TC, Scharp DW, Lacy PE, Ogren L, Talamantes F, Robertson M, Friesen HG, Sorenson RL 1993 Effect of homologous placental lactogens, prolactins, and growth hormones on islet B-cell division and insulin secretion in rat, mouse, and human islets: implication for placental lactogen regulation of islet function during pregnancy. Endocrinology 132:879-887
50. Brelje TC, Parsons JA, Sorenson RL 1994 Regulation of islet β-cell proliferation by prolactin in rat islets. Diabetes 43:263-273
51. Zechner R, Strauss JG, Haemmerle G, Lass A, Zimmermann R 2005 Lipolysis: pathway under construction. Curr Opin Lipidol 16:333-340
52. Yeaman SJ 2004 Hormone-sensitive lipase: new roles for an old enzyme. Biochem J 379:11-22
53. Holm C 2003 Molecular mechanisms regulating hormone-sensitive lipase and lipolysis. Biochem Soc Trans 31:1120-1124