Apolipoprotein E knockout mice have accentuated malnutrition with mucosal disruption and blunted insulin-like growth factor I responses to refeeding

Nutrition Research

Volumn 26, Issue 8, 2006, Pages 427-435

  Oriá, Reinaldo B ^a,b   Vieira, Carlos Meton G ^a   Pinkerton, Relana C ^a   de Castro Costa, Carlos M ^b   Lopes, Maria Beatriz ^a   Hussaini, Isa ^a   Shi, Weibin ^a   Brito, Gerly A C ^b   Lima, Aldo A M ^a,b   Guerrant, Richard L ^a,b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

Author keywords

ApoE; Growing mice; IGF 1; Malnutrition; Small intestine

Indexed keywords

APOLIPOPROTEIN E; SOMATOMEDIN C;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GROWTH DISORDER; ILEUM; INTESTINE ADAPTATION; INTESTINE CRYPT; INTESTINE MUCOSA; INTESTINE VILLUS; KNOCKOUT MOUSE; LACTATION; MALNUTRITION; MOUSE; NONHUMAN; PERINATAL PERIOD; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; REFEEDING; WILD TYPE;

ANIMALIA;

EID: 33748741002     PISSN: 02715317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nutres.2006.06.020     Document Type: Article

References (53)

1. Mahley R.W., and Rall Jr. S.C. Apolipoprotein E: far more than a lipid transport protein. Annu Rev Genomics Hum Genet 1 (2000) 507-537
2. Strittmatter W.J., and Bova H.C. Molecular biology of apolipoprotein E. Curr Opin Lipidol 13 (2002) 119-123
3. DeMattos R.B., Rudel L.L., and Williams D.L. Biochemical analysis of cell-derived apoE3 particles active in stimulating neurite outgrowth. J Lipid Res 42 (2001) 976-987
4. Hussain M.M., Strickland D.K., and Bakillah A. The mammalian low-density lipoprotein receptor family. Annu Rev Nutr 19 (1999) 141-172
5. Umans L., Serneels L., Lorent K., Dewachter I., Tesseur I., Moechars D., et al. Lipoprotein receptor-related protein in brain and in cultured neurons of mice deficient in receptor-associated protein and transgenic for apolipoprotein E4 or amyloid precursor protein. Neuroscience 94 (1999) 315-321
6. McCarron M.O., Hoffmann K.L., DeLong D.M., Gray L., Saunders A.M., and Alberts M.J. Intracerebral hemorrhage outcome: apolipoprotein E genotype, hematoma, and edema volumes. Neurology 53 (1999) 2176-2179
7. Lomnitski L., Chapman S., Hochman A., Kohen R., Shohami E., Chen Y., et al. Antioxidant mechanisms in apolipoprotein E deficient mice prior to and following closed head injury. Biochim Biophys Acta 1453 (1999) 359-368
8. Russo C., Angelini G., Dapino D., Piccini A., Piombo G., Schettini G., et al. Opposite roles of apolipoprotein E in normal brains and in Alzheimer's disease. Proc Natl Acad Sci U S A 95 (1998) 15598-15602
9. Nathan B.P., Jiang Y., Wong G.K., Shen F., Brewer G.J., and Struble R.G. Apolipoprotein E4 inhibits, and apolipoprotein E3 promotes neurite outgrowth in cultured adult mouse cortical neurons through the low-density lipoprotein receptor-related protein. Brain Res 928 (2002) 96-105
10. Nathan B.P., Chang K.C., Bellosta S., Brisch E., Ge N., Mahley R.W., et al. The inhibitory effect of apolipoprotein E4 on neurite outgrowth is associated with microtubule depolymerization. J Biol Chem 270 (1995) 19791-19799
11. Mangeney M., Cardot P., Lyonnet S., Coupe C., Benarous R., Munnich A., et al. Apolipoprotein-E-gene expression in rat liver during development in relation to insulin and glucagon. Eur J Biochem 181 (1989) 225-230
12. Cheng H., and Bjerknes M. Whole population cell kinetics and postnatal development of the mouse intestinal epithelium. Anat Rec 211 (1985) 420-426
13. Al Nafussi A.I., and Wright N.A. Cell kinetics in the mouse small intestine during immediate postnatal life. Virchows Arch B Cell Pathol Incl Mol Pathol 40 (1982) 51-62
14. Wiren M., Soderholm J.D., Lindgren J., Olaison G., Permert J., Yang H., et al. Effects of starvation and bowel resection on paracellular permeability in rat small-bowel mucosa in vitro. Scand J Gastroenterol 34 (1999) 156-162
15. Chappell V.L., Thompson M.D., Jeschke M.G., Chung D.H., Thompson J.C., and Wolf S.E. Effects of incremental starvation on gut mucosa. Dig Dis Sci 48 (2003) 765-769
16. Dou Y., Gregersen S., Zhao J., Zhuang F., and Gregersen H. Effect of re-feeding after starvation on biomechanical properties in rat small intestine. Med Eng Phys 23 (2001) 557-566
17. Ziegler T.R., Mantell M.P., Chow J.C., Rombeau J.L., and Smith R.J. Gut adaptation and the insulin-like growth factor system: regulation by glutamine and IGF-I administration. Am J Physiol 271 (1996) G866-G875
18. Gordon P.V., Price W.A., and Stiles A.D. Dexamethasone administration to newborn mice alters mucosal and muscular morphology in the ileum and modulates IGF-I localization. Pediatr Res 49 (2001) 93-100
19. Dvorak B., Stephana A.L., Holubec H., Williams C.S., Philipps A.F., and Koldovskoy O. Insulin-like growth factor-I (IGF-I) mRNA in the small intestine of suckling and adult rats. FEBS Lett 388 (1996) 155-160
20. Su Z., Li Y., James J.C., McDuffie M., Matsumoto A.H., Helm G.A., et al. Quantitative trait locus analysis of atherosclerosis in an intercross between C57BL/6 and C3H mice carrying the mutant apolipoprotein E gene. Genetics 172 (2006) 1799-1807
21. Calikoglu A., Karayal A., and D'Ercole A. Nutritional regulation of IGF-I expression during brain development in mice. Pediatr Res 49 (2001) 197-202
22. Carneiro-Filho B.A., Oria R.B., Wood R.K., Brito G.A., Fujii J., Obrig T., et al. Alanyl-glutamine hastens morphologic recovery from 5-fluorouracil-induced mucositis in mice. Nutrition 20 (2004) 934-941
23. Ludbrook J. Multiple comparison procedures updated. Clin Exp Pharmacol Physiol 25 (1998) 1032-1037
24. Yamauchi K., Tozuka M., Nakabayashi T., Sugano M., Hidaka H., Kondo Y., et al. Apolipoprotein E in cerebrospinal fluid: relation to phenotype and plasma apolipoprotein E concentrations. Clin Chem 45 (1999) 497-504
25. Wilson C., Wardell M.R., Weisgraber K.H., Mahley R.W., and Agard D.A. Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E. Science 252 (1991) 1817-1822
26. Fullerton S.M., Shirman G.A., Strittmatter W.J., and Matthew W.D. Impairment of the blood-nerve and blood-brain barriers in apolipoprotein e knockout mice. Exp Neurol 169 (2001) 13-22
27. Teasdale G.M., Nicoll J.A., Murray G., and Fiddes M. Association of apolipoprotein E polymorphism with outcome after head injury. Lancet 350 (1997) 1069-1071
28. Liberman J.N., Stewart W.F., Wesnes K., and Troncoso J. Apolipoprotein E epsilon 4 and short-term recovery from predominantly mild brain injury. Neurology 58 (2002) 1038-1044
29. Poirier J. Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease. Trends Neurosci 17 (1994) 525-530
30. Poirier J., Hess M., May P.C., and Finch C.E. Astrocytic apolipoprotein E mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning. Brain Res Mol Brain Res 11 (1991) 97-106
31. LeBlanc A.C., and Poduslo J.F. Regulation of apolipoprotein E gene expression after injury of the rat sciatic nerve. J Neurosci Res 25 (1990) 162-171
32. Gutman C.R., Strittmatter W.J., Weisgraber K.H., and Matthew W.D. Apolipoprotein E binds to and potentiates the biological activity of ciliary neurotrophic factor. J Neurosci 17 (1997) 6114-6121
33. Gordon P.V., Paxton J.B., Herman A.C., Carlisle E.M., and Fox N.S. Igf-I accelerates ileal epithelial cell migration in culture and newborn mice and may be a mediator of steroid-induced maturation. Pediatr Res 55 (2004) 34-41
34. Lund P.K. Molecular basis of intestinal adaptation: the role of the insulin-like growth factor system. Ann N Y Acad Sci 859 (1998) 18-36
35. Arola L., Palou A., Remesar X., and Alemany M. Changes in glutamine synthesis activity in the different organs of developing rats. Arch Int Physiol Biochim 89 (1981) 189-194
36. Ball P.A., and Hardy G. Glutamine in pediatrics: where next?. Nutrition 18 (2002) 451-454
37. Madej M., Lundh T., and Lindberg J.E. Activities of enzymes involved in glutamine metabolism in connection with energy production in the gastrointestinal tract epithelium of newborn, suckling and weaned piglets. Biol Neonate 75 (1999) 250-258
38. Nagy L.E., and Kretchmer N. Utilization of glutamine in the developing rat jejunum. J Nutr 118 (1988) 189-193
39. Shenoy V., Roig J.C., Kubilis P., and Neu J. Characterization of glutaminase in the developing rat small intestine. J Nutr 126 (1996) 1121S-1130S
40. Prack M.M., Nicosia M., Williams D.L., and Gwynne J. Relationship between apolipoprotein E mRNA expression and tissue cholesterol content in rat adrenal gland. J Lipid Res 32 (1991) 1611-1618
41. Raber J., Akana S.F., Bhatnagar S., Dallman M.F., Wong D., and Mucke L. Hypothalamic-pituitary-adrenal dysfunction in Apoe(-/-) mice: possible role in behavioral and metabolic alterations. J Neurosci 20 (2000) 2064-2071
42. Neu J., Walker W.R., Engelhardt E.L., Wu-Wang C.Y., Roa M.B., Thomas M.R., et al. Alterations in piglet small intestine after cholesterol deprivation. Pediatr Res 22 (1987) 330-334
43. Engelhardt E.L., Neu J., Sankar M.B., Gimotty P.A., and Meyer J.W. Changes in phospholipid and cholesterol concentrations of the rat microvillus membrane during maturation. J Pediatr Gastroenterol Nutr 9 (1989) 89-93
44. Reisher S.R., Hughes T.E., Ordovas J.M., Schaefer E.J., and Feinstein S.I. Increased expression of apolipoprotein genes accompanies differentiation in the intestinal cell line Caco-2. Proc Natl Acad Sci U S A 90 (1993) 5757-5761
45. Niemi M., Hakkinen T., Karttunen T.J., Eskelinen S., Kervinen K., Savolainen M.J., et al. Apolipoprotein E and colon cancer. Expression in normal and malignant human intestine and effect on cultured human colonic adenocarcinoma cells. Eur J Intern Med 13 (2002) 37-43
46. Methia N., Andre P., Hafezi-Moghadam A., Economopoulos M., Thomas K.L., and Wagner D.D. ApoE deficiency compromises the blood brain barrier especially after injury. Mol Med 7 (2001) 810-815
47. D'Harlingue A.E., Kwong L.K., Morrill J.S., Sunshine P., and Tsuboi K.K. Growth and differentiative maturation of the rat enterocyte. J Pediatr Gastroenterol Nutr 5 (1986) 956-963
48. Meddings J.B., and Theisen S. Development of rat jejunum: lipid permeability, physical properties, and chemical composition. Am J Physiol 256 (1989) G931-G940
49. Ripolles P.B., Nazih H., Neunlist M., Huvelin J.M., and Bard J.M. Effect of LPS on basal and induced apo E secretion by 25-OH chol and 9cRA in differentiated CaCo-2. J Cell Biochem 91 (2004) 786-795
50. Carroll P.V., Jackson N.C., Russell-Jones D.L., Treacher D.F., Sonksen P.H., and Umpleby A.M. Combined growth hormone/insulin-like growth factor I in addition to glutamine-supplemented TPN results in net protein anabolism in critical illness. Am J Physiol Endocrinol Metab 286 (2004) E151-E157
51. Winesett D.E., Ulshen M.H., Hoyt E.C., Mohapatra N.K., Fuller C.R., and Lund P.K. Regulation and localization of the insulin-like growth factor system in small bowel during altered nutrient status. Am J Physiol 268 (1995) G631-G640
52. Ziegler T.R., Evans M.E., Fernandez-Estivariz C., and Jones D.P. Trophic and cytoprotective nutrition for intestinal adaptation, mucosal repair, and barrier function. Annu Rev Nutr 23 (2003) 229-261
53. Oria R.B., Patrick P.D., Zhang H., Lorntz B., Castro Costa C.M., Brito G.A., et al. APOE4 protects the cognitive development in children with heavy diarrhea burdens in Northeast Brazil. Pediatr Res 57 (2005) 310-316