Monitoring biological effects of pollution in the Baltic Sea: Neglected-but still wanted?

Marine Pollution Bulletin

Volumn 53, Issue 8-9, 2006, Pages 377-386

  Lehtonen, Kari K ^a   Schiedek, Doris ^b  

^a FINNISH INSTITUTE OF MARINE RESEARCH   (Finland)

^b LEIBNIZ INSTITUTE FOR BALTIC SEA RESEARCH   (Germany)

Author keywords

Baltic Sea; Biological effects; Biomarkers; Monitoring; Pollution

Indexed keywords

BIOLOGICAL EFFECTS; COASTAL WATERS; ENVIRONMENTAL MONITORING; MONITORING STRATEGY;

COASTAL ZONES; ENVIRONMENTAL IMPACT; EUTROPHICATION; HYDROGRAPHIC SURVEYS; IMPURITIES;

MARINE POLLUTION;

BIOLOGICAL MARKER; ENDOCRINE DISRUPTOR;

BIOLOGICAL METHOD; COASTAL WATER; EUTROPHICATION; MONITORING; POLLUTION EFFECT; RESEARCH WORK;

ARTICLE; BALTIC SEA; BIOLOGICAL MONITORING; COASTAL WATERS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; EUROPE; EUTROPHICATION; MARINE ENVIRONMENT; METHODOLOGY; NONHUMAN; POLLUTION MONITORING; SEA POLLUTION; SEASONAL VARIATION;

BALTIC STATES; BIOLOGICAL MARKERS; ENVIRONMENTAL MONITORING; OCEANS AND SEAS; SEAWATER; WATER POLLUTANTS, CHEMICAL;

ATLANTIC OCEAN; BALTIC SEA;

EID: 33748714957     PISSN: 0025326X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.marpolbul.2005.11.016     Document Type: Article

References (113)

1. Aas E., Baussant T., Balk L., Liewenborg B., and Andersen O.K. PAH metabolites in bile, cytochrome P4501A and DNA adducts as environmental risk parameters for chronic oil exposure: a laboratory experiment with Atlantic cod. Aquatic Toxicology 51 (2000) 241-258
2. Aas E., Beyer J., Jonsson G., Reichert W.L., and Andersen O.K. Evidence of uptake, biotransformation and DNA binding of polyaromatic hydrocarbons in Atlantic cod and corkwing wrasse caught in the vicinity of an aluminium works. Marine Environmental Research 52 (2001) 213-229
3. Ærtebjerg G., Andersen J.H., and Schou Hansen O. Nutrients and Eutrophication in Danish Marine Waters. A Challenge for Science and Management (2003), National Environmental Research Institute 125 pp
4. Al-Sabti K., and Hardig J. Micronucleus test in fish for monitoring the genotoxic effects of industrial waste products in the Baltic Sea, Sweden. Comparative Biochemistry and Physiology 97C (1990) 179-182
5. Andersson T., Förlin T., Herdig J., and Larson A. Physiological disturbances in fish living in coastal water polluted with bleached pulp mill effluents. Canadian Journal for Fisheries and Aquatic Sciences 45 (1988) 1525-1546
6. Balk L., Andersson T., Förlin L., Söderström M., and Larsson Å. Indications of regional and large-scale biological effects caused by bleached pulp mill effluents. Chemosphere 27 (1993) 631-650
7. Balk, L., Ericson, G., Lindesjöö, E., Petterson, I., Tjärnlund, U., Åkerman, G., 1994. Effects of exhaust from two-stroke outboard engines on fish. Studies of genotoxic, enzymatic, physiological and histological disorders at the individual level. TemaNord 1994, 528. ISBN 9-29120-439-0, 66 pp.
8. Balk L., Larsson Å., and Förlin L. Baseline studies of biomarkers in the feral female perch (Perca fluviatilis) as tools in biological monitoring of anthropogenic substances. Marine Environmental Research 42 (1996) 203-208
9. Baršienė J. Genotoxic impacts in Klaipeda marine port and Bover(u, ̄)tinge oil terminal areas (Baltic Sea). Marine Environmental Research 54 (2002) 475-479
10. Baršienė J., Lazutka J., Šyvokienė J., Dedonytė V., Rybakovas A., Bjornstad A., and Andersen O.K. Analysis of micronuclei in blue mussels and fish from the Baltic and the North Seas. Environmental Toxicology 19 (2004) 365-371
11. Baršienė, J., Lehtonen, K.K., Koehler, A., Broeg, K., Vuorinen, P.J., Lang, T., Pempkowiak, J., Šyvokienė, J., Dedonyte, V., Rybakovas, A., Repečka, R., Vuontisjärvi, H., Kopecka, J., 2006a. Biomarker responses in flounder (Platichthys flesus) and mussel (Mytilus edulis) in the Klaipėda-Būtingė area (Baltic Sea). Marine Pollution Bulletin (this volume).
12. Baršienė, J., Schiedek, D., Rybakovas, A., Šyvokienė, J., Kopecka, J., Förlin, L., 2006b. Cytogenetic and cytotoxic effects in gill cells of the blue mussel Mytilus spp. from different zones of the Baltic Sea. Marine Pollution Bulletin (this volume), doi:10.1016/j.marpolbul.2005.11.015.
13. Bocquené G., and Galgani F. Biological effects of contaminants: cholinesterase inhibition by organophosphate and carbamate compounds. ICES Techniques in Marine Environmental Sciences (1998) 22
14. Bogovski S., Sergeyev B., Muzyka V., and Karlova S. Correlations between cytochrome P450, haem synthesis enzymes, and aromatic compounds in flounder (Platichthys flesus) from the Baltic Sea. ICES Journal of Marine Science 56 (1999) 152-156
15. Bohling P., Hudd R., Lehtonen H., Karas P., Neuman E., and Thoresson G. Variations in year-class strength of different perch (Perca fluviatilis) populations in the Baltic Sea with special reference to temperature and pollution. Canadian Journal of Fisheries and Aquatic Sciences 48 (1991) 1181-1187
16. Bolognesi C., Frenzilli G., Lasagna C., Perrone E., and Roggieri P. Genotoxicity biomarkers in Mytilus galloprovincialis: wild versus caged mussels. Mutation Research 552 (2004) 153-162
17. Bouilly K., Leitao A., McCombie H., and Lapegue S. Impact of atrazine on aneuploidy in Pacific oysters, Crassostrea gigas. Environmental Toxicology and Chemistry 22 (2003) 219-223
18. Bradley B.P., Olsson B., Brown D.C., and Tedengren M. HSP70 levels in physiologically stressed Baltic Sea mussels. Marine Environmental Research 46 (1998) 397-400
19. Breitholtz M., Hill C., and Bengtsson B.-E. Toxic substances and reproductive disorders in Baltic fish and crustaceans. Ambio 30 (2001) 210-216
20. Broeg, K., Lehtonen, K.K., 2006. Indices for the assessment of environmental pollution of the Baltic Sea coasts: integrated assessment of a multi-biomarker approach. Marine Pollution Bulletin (this volume).
21. Cajaraville M.P., Bebianno M.J., Blasco J., Porte C., Sarasquete C., and Viarengo A. The use of biomarkers to assess the impact of pollution in coastal environments of the Iberian Peninsula: a practical approach. Science of the Total Environment 247 (2000) 295-311
22. Carr R.S., and Lindén O. Bioenergetic responses of Gammarus salinus and Mytilus edulis to oil and oil dispersants in a model ecosystem. Marine Ecology Progress Series 19 (1984) 285-291
23. Cavaletto M., Ghezzi A., Burlando B., Evangelisti V., Ceratto N., and Viarengo A. Effect of hydrogen peroxide on antioxidant enzymes and metallothionein level in the digestive gland of Mytilus galloprovincialis. Comparative Biochemistry and Physiology C 131 (2002) 447-455
24. Cossa D. A review of the use of Mytilus spp. as quantitative indicators of cadmium and mercury contamination in coastal waters. Oceanologica Acta 12 (1989) 417-432
25. den Besten P.J. Concepts for the implementation of biomarkers in environmental monitoring. Marine Environmental Research 46 (1998) 253-256
26. Depledge, M., 1990. Interactions between heavy metals and physiological processes in estuarine invertebrates. In: Chambers, P.L., Chambers, C.M., (Eds.), Estuarine Ecotoxicology, pp. 89-100.
27. Depledge M., and Galloway T.S. Healthy animals, healthy ecosystems. Frontiers in Ecology and Environment 3 (2005) 251-258
28. Directive 2000/60/EC, 2000. Directive 2000/60/EC of the European Parliament and of the Council of 23 October 2000 establishing a framework for Community Action in the field of Water Policy. OJEC 327, pp. 1-72.
29. Elmgren R. Understanding human impact on the Baltic ecosystem: changing views in recent decades. Ambio 30 (2001) 222-231
30. 32P-postlabeling analysis of DNA adducts in Perch (Perca fluviatilis) from unpolluted and polluted areas in Swedish coastal waters. Marine Environmental Research 39 (1995) 303-307
31. Ericson G., Åkerman G., Liewenborg B., and Balk L. Comparison of DNA damage in the early life stages of cod, Gadus morhua, originating from Barents Sea and Baltic Sea. Marine Environmental Research 42 (1996) 119-123
32. Ericson G., Lindesjöö E., and Balk L. DNA adducts and histopathological lesions in perch (Perca fluviatilis) and northern pike (Esox lucius) along a polycyclic aromatic hydrocarbon gradient on the Swedish coastline of the Baltic Sea. Canadian Journal of Fisheries and Aquatic Sciences 55 (1998) 815-824
33. Ericson G., Noaksson E., and Balk L. DNA adduct formation and persistence in liver and extrahepatic tissues of northern pike (Esox lucius) following oral exposure to benzo(a)pyrene, benzo(k)fluoranthene and 7H-dibenzo(c,g)carbazole. Mutation Research 47 (1999) 135-145
34. Ericson G., Liewenborg B., Lindesjöö E., Näf C., and Balk L. DNA adducts in perch (Perca fluviatilis) from a creosote contaminated site in the River Ångermanälven, Sweden. Aquatic Toxicology 45 (1999) 181-193
35. Eriksson Wiklund A.-K., and Sundelin B. Impaired reproduction in the amphipods Monoporeia affinis and Pontoporeia femorata as of result of moderate hypoxia and increased temperature. Marine Ecology Progress Series 222 (2001) 131-141
36. Eriksson Wiklund A.-K., and Sundelin B. Biomarker sensitivity to temperature and hypoxia-a seven year field study. Marine Ecology Progress Series 274 (2004) 209-214
37. Förlin L., Andersson T., Balk L., and Larsson A. Biochemical and physiological effects in fish exposed to bleached kraft mill effluents. Ecotoxicology and Environmental Safety 30 (1995) 164-170
38. Fulton M.H., and Key P.B. Acetylcholinesterase inhibition in estuarine fish and invertebrates as an indicator of organophosphorus insecticide exposure and effects. Environmental Toxicology and Chemistry 20 (2001) 37-45
39. Galgani F., and Bocquené G. Molecular biomarkers of exposure of marine organisms to organophosphorus pesticides and carbamates. In: Lagadic L. (Ed). Use of Biomarkers for Environmental Quality Assessment (2000), Elsevier Science Publisher 113-137
40. Galloway T.S., Sanger R.C., Smith K.L., Fillmann G., Readman J.W., Ford T.E., and Depledge M.H. Rapid assessment of marine pollution using multiple biomarkers and chemical immunoassays. Environmental Science and Technology 36 (2002) 2219-2226
41. Galloway T.S., Brown R.J., Browne M.A., Dissanayake A., Lowe D., and Depledge M.H. A multibiomarker approach to environmental assessment. Environmental Science and Technology 38 (2004) 1723-1731
42. Gercken J., and Sordyl H. Intersex in feral marine and freshwater fish from northeastern Germany. Marine Environmental Research 54 (2002) 651-655
43. Gercken, J., Förlin, L., Andersson, J., 2006. Developmental disorders in larvae of eelpout (Zoarces viviparus) from German and Swedish Baltic coastal waters. Marine Pollution Bulletin (this volume), doi:10.1016/j.marpolbul.2005.11.009.
44. Gilek M., Tedengren M., and Kautsky N. Physiological performance and general histology of the blue mussel, Mytilus edulis L., from the Baltic and North Seas. Netherlands Journal of Sea Research 30 (1992) 11-21
45. Handy R.D., Galloway T.S., and Depledge M.H. A proposal for the use of biomarkers for the assessment of chronic pollution and in regulatory toxicology. Ecotoxicology 12 (2003) 331-341
46. Hansson, T., Schiedek, D., Lehtonen, K.K., Vuorinen, P.J., Liewenborg, B., Noaksson, E., Tjärnlund, U., Hanson, M., Balk, L., 2006. Biochemical biomarkers in adult female perch (Perca fluviatilis) in a chronically polluted gradient in the Stockholm recipient (Sweden). Marine Pollution Bulletin (this volume).
47. HELCOM, 2002. Environment of the Baltic Sea Area 1994-1998. Baltic Sea Environment Proceedings No. 82B, 216 pp.
48. HELCOM, 2003. The Baltic Marine Environment 1999-2002. Baltic Sea Environment Proceedings No. 87, 48 pp.
49. HELCOM, 2005. Helsinki Commission HELCOM MON-PRO 2/2005 Project to Review the HELCOM Monitoring and Assessment Programmes. Second Meeting, Stockholm, Sweden, 14-18 February 2005, 30 pp.
50. In: Huggert R.J., Kimerle R.A., Mehrle P.M., and Bergman H.L. (Eds). Biomarkers: Biochemical, Physiological and Histological Markers of Anthropogenic Stress (1992), Lewis Publishers, Boca Raton, FL 347 pp
51. Hyyti O.M., Nyman M., Willis M.L., Raunio H., and Pelkonen O. Distribution of cytochrome P4501A (CYP1A) in the tissues of Baltic ringed and grey seals. Marine Environmental Research 51 (2001) 465-485
52. Jansson B.-O., and Dahlberg K. The environmental status of the Baltic Sea in the 1940s, today and in the future. Ambio 28 (1999) 312-319
53. Jha A.N. Genotoxicological studies in aquatic organisms: an overview. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 552 (2004) 1-17
54. Kopecka, J., Lehtonen, K.K., Baršienė, J., Broeg K., Vuorinen P.J., Gercken, J., Pempkowiak, J., 2006. Measurements of biomarker levels in flounder (Platichthys flesus) and blue mussel (Mytilus trossulus) from the Gulf of Gdańsk (Southern Baltic). Marine Pollution Bulletin (this volume).
55. Lam P.K.S., and Gray J. The use of biomarkers in environmental monitoring programmes. Marine Pollution Bulletin 46 (2003) 182-186
56. Lang T., Mellergaard S., Wosniok W., Kadakas V., and Neumann K. Spatial distribution of grossly visible diseases and parasites in flounder (Platichthys flesus) from the Baltic Sea: a synoptic study. ICES Journal of Marine Science 56 (1999) 138-147
57. Lang, T., Wosniok, W., Baršienė, J., Broeg, K., Förlin, L., Köhler, A., Kopecka, J., Lehtonen, K.K., Pempkowiak, J., Schiedek, D., Schneider, R., Vuorinen, P.J., in preparation. Multi-biomarker measurements in offshore flounder (Platichthys flesus) from the Baltic Sea.
58. Lang, T., Wosniok, W., Baršienė, J., Broeg, K., Kopecka, J., Parkkonen, J., 2006. Liver histopathology in Baltic flounder (Platichthys flesus) as indicator of biological effects of contaminants. Marine Pollution Bulletin (this volume).
59. Larsson D.G.J., Adolfsson-Erici M., Parkkonen J., Pettersson M., Berg A.H., Olsson P.E., and Förlin L. Ethinylestradiol- and undesired fish contraceptive?. Aquatic Toxicology 45 (1999) 91-97
60. Larsson D.G.J., Hällman H., and Förlin L. Skewed embryonic sex ratios in a viviparous fish: a result of endocrine disruption?. Marine Environmental Research 50 (2000) 191-192
61. Larsson D.G.J., and Förlin L. Male-biased sex ratios of fish embryos near a pulp mill: temporary recovery after a short-term shutdown. Environmental Health Perspectives 110 (2002) 739-742
62. Laughlin R., and Lindén O. Oil pollution and Baltic mysids: acute and chronic effects of water soluble fractions of light fuel oil on the mysid shrimp Neomysis integer. Marine Ecology Progress Series 12 (1983) 29-41
63. Lehtinen K.-J., and Oikari A. Sublethal effects of kraft pulp mill waste water on the perch, Perca fluviatilis, studied by rotary-flow and histological techniques. Annales Zoologici Fennici 17 (1980) 255-259
64. Lehtonen K.K., and Leiniö S. Effects of exposure to copper and malathion on metallothionein levels and acetylcholinesterase activity of the mussel Mytilus edulis and the clam Macoma balthica from the northern Baltic Sea. Bulletin of Environmental Contamination and Toxicology 71 (2003) 489-496
65. Lehtonen, K.K., Leiniö, S., Schneider, R., Leivuori, M., in preparation. Biomarkers of pollution effects in the bivalves Mytilus edulis and Macoma balthica collected from two areas in the southern coast of Finland (Baltic Sea).
66. Lehtonen, K.K., Schiedek, D., Koehler, A., Lang, T., Vuorinen, P.J., Förlin, L., Baršienė, J., Pempkowiak, J., Gercken, J., 2006. The BEEP project in the Baltic Sea: overview of results and outline for a regional biological effects monitoring strategy. Marine Pollution Bulletin (this volume).
67. Li H., Boon J.P., Lewis W.E., Van Den Berg M., Nyman M., and Letcher R.J. Hepatic microsomal cytochrome P450 enzyme activity in relation to in vitro metabolism/inhibition of polychlorinated biphenyls and testosterone in Baltic grey seal (Halichoerus grypus). Environmental Toxicology and Chemistry 22 (2003) 636-644
68. Lindesjöö, E., 1992. Fish diseases and pulp mill effluents: epidemiological and histological studies. PhD Thesis, Uppsala University, Sweden, 39 pp.
69. Lindesjöö E., Thulin J., Bengtsson B.-E., and Tjärnlund U. Abnormalities of a gill cover bone, the operculum, in perch (Perca fluviatilis) from a pulp mill effluent area. Aquatic Toxicology 28 (1994) 189-207
70. Lyons C., Dowling V., Tedengren M., Gardeström J., Hartl M.G.J., O'Brien N., Van Pelt F.N.A.M., O'Halloran J., and Sheehan D. Variability of heat shock proteins and glutathione S-transferase in gill and digestive gland of blue mussel, Mytilus edulis. Marine Environmental Research 56 (2003) 585-597
71. Matthiessen P. Endocrine disruption in fish. Pure and Applied Chemistry 75 (2003) 2249-2261
72. McCarthy J.F., and Shugart L.R. Biomarkers of Environmental Contamination (1990), Lewis Publishers, Boca Raton, FL, USA
73. McLusky D.D., Bryant V., and Campbell R. The effect of temperature and salinity on the toxicity of heavy metals to marine and estuarine invertebrates. Oceanography and Marine Biology Annual Review 24 (1986) 481-520
74. Moore M.N., Lowe D., and Koehler A. Biological effects of contaminants: measurements of lysosomal membrane stability. ICES Techniques in Marine Environmental Sciences 36 (2004) 31 pp
75. Munter, K., Autio, L., Lehtonen, K.K., Dahllöf, I., submitted for publication. TBT and heavy metal contamination in sediments and clams (Macoma balthica) and biomarker responses in clams off shipyards and marinas off Helsinki, the Gulf of Finland.
76. Napierska D., and Radlowska M. Stress proteins induced by cadmium in the abdominal muscle of the shrimp Crangon crangon. Oceanologia 40 (1998) 157-162
77. Narbonne J.F., Daubeze M., Clerandeau C., and Garrigues P. Scale of classification based on biochemical markers in mussels: application to pollution monitoring in European coasts. Biomarkers 4 (1999) 415-424
78. Nyman M., Bergknut M., Fant M.L., Raunio H., Jestoi M., Bengs C., Murk A., Koistinen J., Backman C., Pelkonen O., Tysklind M., Hirvi T., and Helle E. Contaminant exposure and effects in Baltic ringed and grey seals as assessed by biomarkers. Marine Environmental Research 55 (2003) 73-99
79. Nyman M., Raunio H., Taavitsainen P., and Pelkonen O. Characterization of xenobiotic-metabolizing cytochrome P450 (CYP) forms in ringed and grey seals from the Baltic Sea and reference sites. Comparative Biochemistry and Physiology C 128 (2001) 99-112
80. Oberdörster E., and Cheek A.O. Gender benders at the beach: endocrine disruption in marine and estuarine organisms. Environmental Toxicology and Chemistry 20 (2000) 23-36
81. Olsson B., Bradley B.P., Gilek M., Reimer O., Shepard J.L., and Tedengren M. Physiological and proteomic responses in Mytilus edulis exposed to PCBs and PAHs extracted from Baltic Sea sediments. Hydrobiologia 514 (2004) 15-27
82. Parkkonen J., Larsson D.G.J., Adolfsson-Erici M., Petterson M., Berg A.H., Olsson P.-E., and Förlin L. Contraceptive pill residues in sewage effluent are estrogenic to fish. Reproductive Physiology of Fish (2000) 362-364
83. Peters E.C., and Lehtonen K.K. Chemical and other stressors in the Gulf of Riga: Interpreting multiple lesions in the clam Macoma balthica. Journal of Shellfish Research 16 (1997) 351
84. Pohl C., and Hennings U. The effect of redox processes on the partitioning of Cd, Pb, Cu, and Mn between dissolved and particulate phases in the Baltic Sea. Marine Chemistry 65 (1999) 41-53
85. Porte C., Solé M., Borghi V., Martinez M., Chamorro J., Torreblanca A., Ortiz M., Orbea A., Soto M., and Cajaraville M.P. Chemical, biochemical and cellular responses in the digestive gland of the mussel Mytilus galloprovincialis from the Spanish Mediterranean coast. Biomarkers 6 (2001) 335-350
86. Radlowska M., and Pempkowiak J. Stress-70 as indicator of heavy metals accumulation in blue mussel Mytilus edulis. Environment International 27 (2002) 605-608
87. Remane A., and Schlieper C. The Biology of Brackish Waters. second ed. (1971), Wiley Interscience, New York 372 pp
88. Roesijadi G. Metallothioneins in metal regulation and toxicity in aquatic animals. Aquatic Toxicology 22 (1992) 81-114
89. Ronisz, D., Larsson, D.G.J., Förlin, L, 1999. Seasonal variations in the activities of selected hepatic biotransformation and antioxidant enzymes in eelpout (Zoarces viviparus). Comparative Biochemistry and Physiology C 124, 271-279.
90. Ross P.S., de Swart R.L., Reijnders P.J.H., Van Loveren H., Vos J.G., and Osterhaus A.D.M.E. Contaminant-related suppression of delayed type hypersensitivity and antibody responses in harbour seals fed herring from the Baltic Sea. Environmental Health Perspectives 103 (1995) 162-167
91. Sandström O., Abrahamsson I., Andersson J., and Vetemaa M. Temperature effects on spawning and egg development in Eurasian perch. Journal of Fish Biology 51 (1997) 1015-1024
92. Sandström O., and Neuman E. Long-term development in a Baltic fish community exposed to bleached pulp mill effluent. Aquatic Ecology 37 (2003) 267-276
93. Schiedek, D., Broeg, K., Baršienė, J., Lehtonen, K.K., Gercken, J., Pfeifer, S., Vuontisjärvi, H., Vuorinen, P.J., Dedonyte, V., Koehler, A., Balk, L., Schneider, R., 2006. Biomarker responses as indication of contaminant effects in blue mussel (Mytilus edulis) and female eelpout (Zoarces viviparus) from the southwestern Baltic Sea. Marine Pollution Bulletin (this volume), doi:10.1016/j.marpolbul.2005.11.013.
94. Schulte-Oehlmann U., Oehlmann J., Bauer B., Fioroni P., and Leffler U.S. Toxico-kinetic and -dynamic aspects of TBT-induced imposex in Hydrobia ulvae compared with intersex in Littorina littorea (Gastropoda, Prosobranchia). Hydrobiologia 378 (1998) 215-225
95. Selin H., and VanDeveer S.D. Baltic Sea hazardous substances management: results and challanges. Ambio 33 (2004) 153-160
96. Shepard J.L., and Bradley B.P. Protein expression signatures and lysosomal stability in Mytilus edulis exposed to graded copper concentrations. Marine Environmental Research 50 (2000) 457-463
97. Shepard J.L., Olsson B., Tedengren M., and Bradley B.P. Protein expression signatures identified in Mytilus edulis exposed to PCBs, copper and salinity stress. Marine Environmental Research 50 (2000) 337-340
98. Sokolowski A., Wolowicz M., Hummel H., Smolarz-Gorska K., Fichet D., Radenac G., Thiriot-Quievreux C., and Namiesnik J. Abnormal features of Macoma balthica (Bivalvia) in the Baltic Sea: alerting symptoms of environmental adversity?. Marine Pollution Bulletin 49 (2004) 17-22
99. Strand J., and Jacobsen J.A. Imposex in two sublittoral neogastropods from the Kattegat and Skagerrak: the common whelk Buccinum undatum and the red whelk Neptunea antiqua. Marine Ecology Progress Series 244 (2002) 171-177
100. Strand J., Jacobsen J.A., Pedersen B., and Granmo A. Butyltin compounds in sediment and molluscs from the shipping strait between Denmark and Sweden. Environmental Pollution 124 (2003) 7-15
101. Skarpheinsdottir H., Ericson G., Dalla Zuanna L., and Gilek M. Tissue differences, dose-response relationship and persistence of DNA adducts in blue mussels (Mytilus edulis L.) exposed to benzo[a]pyrene. Aquatic Toxicology 62 (2003) 165-177
102. Sundelin B., and Eriksson A.-K. Malformations in embryos of the deposit-feeding amphipod Monoporeia affinis in the Baltic Sea. Marine Ecology Progress Series 171 (1998) 165-180
103. Sunila I. Chronic histopathological effects of short-term copper and cadmium exposure on the gill of the mussel, Mytilus edulis. Journal of Invertebrate Pathology 47 (1986) 125-142
104. Sunila I. Acute histological responses of the gill of the mussel, Mytilus edulis, to exposure by environmental pollutants. Journal of Invertebrate Pathology 52 (1988) 137-141
105. Tedengren M., Arnér M., and Kautsky N. Ecophysiology and stress response of marine and brackish water Gammarus species (Crustacea, Amphipoda) to changes in salinity and exposure to cadmium and diesel oil. Marine Ecology Progress Series 47 (1988) 107-116
106. Tedengren M., and Kautsky N. Comparative stress response to diesel oil and salinity changes of the blue mussel, Mytilus edulis from the Baltic and North Seas. Ophelia 28 (1987) 1-9
107. Tedengren M., Olsson B., Bradley B., and Zhou L. Heavy metal uptake, physiological response and survival of the blue mussel (Mytilus edulis) from marine and brackish waters in relation to the induction of heat-shock protein 70. Hydrobiologia 393 (1999) 261-269
108. Tedengren M., Olsson B., Reimer O., Brown D.C., and Bradley B.P. Heat pre-treatment increases cadmium resistance and HSP 70 levels in Baltic Sea mussels. Aquatic Toxicology 48 (2000) 1-12
109. Thiriot-Quievreux C., and Wolowicz M. Chromosomal study of spatial variation of the prevalence of a gill neoplasia in Macoma balthica (L.) from the Gulf of Gdansk (Baltic Sea). Ophelia 54 (2001) 75-81
110. van der Oost R., Beyer J., and Vermeulen N.P.E. Fish bioaccumulation and biomarkers in environmental risk assessment: a review. Environmental Toxicology and Pharmacology 13 (2003) 57-149
111. Viarengo A., Burlano B., Dondero F., Marro A., and Fabbro R. Metallothionein as a tool in biomonitoring programmes. Biomarkers 4 (1999) 455-466
112. Voipio A. The Baltic Sea (1981), Elsevier, Amsterdam
113. Vuorinen, P.J., Keinänen, M., Vuontisjärvi, H., Baršienė, J., Broeg, K., Förlin, L., Gercken, J., Kopecka, J., Köhler, A., Parkkonen, J., Pempkowiak, J., Schiedek, D., 2006. Use of biliary PAH metabolites as a biomarker of pollution in fish from the Baltic Sea. Marine Pollution Bulletin (this volume), doi:10.1016/j.marpolbul.2005.11.020.