Metabolism of myclobutanil and triadimefon by human and rat cytochrome P450 enzymes and liver microsomes

Xenobiotica

Volumn 36, Issue 9, 2006, Pages 793-806

  Barton, H A ^a   Tang, J ^b,c,e   Sey, Y M ^c   Stanko, J P ^b,c   Murrell, R N ^c,d,f   Rockett, J C ^c,g   Dix, D J ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^d NORTH CAROLINA STATE UNIVERSITY   (United States)

^e Cerep Inc   (United States)

^f EAST CAROLINA UNIVERSITY   (United States)

^g ROSETTA INPHARMATICS   (United States)

Author keywords

CYP2C; CYP3A; Cytochrome P450 (CYP); Myclobutanil; Triadimefon

Indexed keywords

ANTIFUNGAL AGENT; CYTOCHROME P450; CYTOCHROME P450 2C; CYTOCHROME P450 3A; MYCLOBUTANIL; PYRROLE DERIVATIVE; TRIADIMEFON; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG CLEARANCE; DRUG HALF LIFE; DRUG METABOLISM; DRUG STRUCTURE; ENZYME SUBSTRATE; FEMALE; HUMAN; LIVER MICROSOME; LIVER WEIGHT; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT;

ANIMALS; BINDING, COMPETITIVE; CYTOCHROME P-450 CYP2B1; FEMALE; FUNGICIDES, INDUSTRIAL; HALF-LIFE; HUMANS; ISOENZYMES; KINETICS; MALE; MICROSOMES, LIVER; NITRILES; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; TRIAZOLES;

EID: 33748701439     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.1080/00498250600821292     Document Type: Article

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