Styrylbenzoazole derivatives for imaging of prion plaques and treatment of transmissible spongiform encephalopathies

Journal of Neurochemistry

Volumn 99, Issue 1, 2006, Pages 198-205

  Ishikawa, Kensuke ^a   Kudo, Yukitsuka ^b   Nishida, Noriyuki ^c   Suemoto, Takahiro ^d   Sawada, Tohru ^d   Iwaki, Toru ^e   Doh Ura, Katsumi ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c NAGASAKI UNIVERSITY   (Japan)

^d BF Research Institute Inc   (Japan)

^e KYUSHU UNIVERSITY   (Japan)

Author keywords

Amyloid imaging; Anti prion activity; Pathogen strain; Prion disease; Styrylbenzoazole derivatives

Indexed keywords

BF 124; BF 125; BF 126; BF 133; BF 135; BF 140; BF 145; BF 148; BF 162; BF 165; BF 166; BF 168; BF 169; BF 173; BF 180; BF 191; BF 208; BF 276; N 282; N 407; N 438; N 457; N 491; PRION PROTEIN; PYRROLE DERIVATIVE; STYRYLBENZOAZOLE DERIVATIVE; STYRYLBENZOIMIDAZOLE DERIVATIVE; STYRYLBENZOTHIAZOLE DERIVATIVE; STYRYLBENZOXAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DRUG EFFICACY; DRUG PENETRATION; HUMAN; HUMAN TISSUE; IC 50; MOUSE; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; SURVIVAL TIME;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BLOOD-BRAIN BARRIER; CELL LINE, TUMOR; CRICETINAE; DISEASE MODELS, ANIMAL; INDICATORS AND REAGENTS; MICE; NEUROBLASTOMA; PRION DISEASES; PRIONS; STYRENES; THIAZOLES;

EID: 33748685214     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04035.x     Document Type: Article

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