Topochemical models for the prediction of permeability through blood-brain barrier

International Journal of Pharmaceutics

Volumn 323, Issue 1-2, 2006, Pages 27-33

  Dureja, H ^a   Madan, A K ^a  

^a MAHARSHI DAYANAND UNIVERSITY   (India)

Author keywords

Blood brain barrier; Eccentric connectivity topochemical index; Molecular connectivity topochemical index; Permeability; Topochemical indices; Wiener's topochemical index

Indexed keywords

APOMORPHINE; ASTEMIZOLE; ATENOLOL; CAREBASTINE; CARMOXIROLE; CHLORPROMAZINE; CLONIDINE; DESIPRAMINE; DOMPERIDONE; DOXYLAMINE; EBASTINE; FLUPENTIXOL; FUROSEMIDE; HALOPERIDOL; IMIPRAMINE; LOPERAMIDE; MEQUITAZINE; NALTREXONE; PERPHENAZINE; PIRENZEPINE; PROMAZINE; PROMETHAZINE; ROXINDOLE; SALBUTAMOL SULFATE; TAMITINOL; TERFENADINE; THIOPENTAL; THIORIDAZINE;

ARTICLE; BLOOD BRAIN BARRIER; CALCULATION; CENTRAL NERVOUS SYSTEM; CHEMICAL STRUCTURE; COMPARATIVE STUDY; COMPUTER ANALYSIS; COMPUTER MODEL; COMPUTER PROGRAM; DATA ANALYSIS; DRUG DESIGN; DRUG PENETRATION; ECCENTRIC CONNECTIVITY TOPOCHEMICAL INDEX; MOLECULAR CONNECTIVITY TOPOCHEMICAL INDEX; MOLECULAR MECHANICS; PREDICTIVE VALIDITY; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STRUCTURE ACTIVITY RELATION; WIENER TOPOCHEMICAL INDEX;

ALGORITHMS; ANIMALS; BLOOD-BRAIN BARRIER; CAPILLARY PERMEABILITY; DRUG DESIGN; HUMANS; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33748677468     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.05.042     Document Type: Article

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