Evaluation of the cytotoxic and pro-apoptotic activities of Eu(III) complexes with appended DNA intercalators in a panel of human malignant cell lines

Medicinal Chemistry

Volumn 2, Issue 5, 2006, Pages 439-445

  Momekov, Georgi ^a   Deligeorgiev, Todor ^b   Vasilev, Aleksey ^b   Peneva, Kalina ^b   Konstantinov, Spiro ^a   Karaivanova, Margarita ^a  

^a MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

^b UNIVERSITY OF SOFIA   (Bulgaria)

Author keywords

diketone; 1,10 phenanthroline; 2,2 bipyridine; Apoptosis; Europium(III); MTT assay

Indexed keywords

1,10 PHENANTHROLINE; 1,3 DIKETONE; 1,3 DIKETONE EUROPIUM DERIVATIVE; 2,2' BIPYRIDINE; ANTINEOPLASTIC AGENT; CISPLATIN; CYTOTOXIC AGENT; DNA FRAGMENT; TRIS(ACETONYLACETONATO)MONO(1,10 PHENANTHROLINE)EUROPIUM; TRIS(ACETONYLACETONATO)MONO(2,2' BIPYRIDINE)EUROPIUM; TRIS(BENZOYLACETONATO)MONO(1,10 PHENANTHROLINE)EUROPIUM; TRIS(BENZOYLACETONATO)MONO(2,2' BIPYRIDINE)EUROPIUM; TRIS(DIBENZOYLMETHANE)MONO(1,10 PHENANTHROLINE)EUROPIUM; TRIS(DIBENZOYLMETHANE)MONO(2,2' BIPYRIDINE)EUROPIUM; TRIS[4,4,4 TRIFLUORO 1 (2 THIENYL) 1,3 BUTANEDIONO]MONO(1,10 PHENANTHROLINE)EUROPIUM; TRIS[4,4,4 TRIFLUORO 1 (2 THIENYL) 1,3 BUTANEDIONO]MONO(2,2' BIPYRIDINE)EUROPIUM; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIOLOGICAL ACTIVITY; BLADDER CARCINOMA; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG DNA BINDING; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; LEUKEMIA; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

APOPTOSIS; CELL LINE, TUMOR; DNA; EUROPIUM; HUMANS; MOLECULAR STRUCTURE; NEOPLASMS;

EID: 33748668802     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340606778250234     Document Type: Article

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